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BMC Psychiatry
Published in: BMC Psychiatry 1/2021

Open Access 01-12-2021 | Research article

Applicability of somatic monitoring instructions in clinical practice guidelines on antipsychotic drug use

Authors: Jurriaan M. J. L. Brouwer, Erien Olde Hengel, Arne J. Risselada, Eric N. van Roon, Hans Mulder

Published in: BMC Psychiatry | Issue 1/2021

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Abstract

Background

Clinical practice guidelines (CPGs) recommend the monitoring of somatic parameters in patients treated with antipsychotic drugs in order to detect adverse effects. The objective of this study was to assess, in adult and (frail) elderly populations, the consistency and applicability of the somatic monitoring instructions recommended by established CPGs prior to and during antipsychotic drug use.

Methods

A search for national and international CPGs was performed by querying the electronic database PubMed and Google. Somatic monitoring instructions were assessed for adult and (frail) elderly populations separately. The applicability of somatic monitoring instructions was assessed using the Systematic Information for Monitoring (SIM) score. Somatic monitoring instructions were considered applicable when a minimum SIM score of 3 was reached.

Results

In total, 16 CPGs were included, with a total of 231 somatic monitoring instructions (mean: 14; range: 0–47). Of the somatic monitoring instructions, 87% were considered applicable, although critical values and how to respond to aberrant values were only present in 28 and 52% of the available instructions respectively. Only 1 CPG presented an instruction specifically for (frail) elderly populations.

Conclusions

We emphasize the need for a guideline with somatic monitoring instructions based on the SIM definition for both adult and (frail) elderly populations using antipsychotic drugs. In addition, CPGs should state that clear agreements should be made regarding who is responsible for interventions and somatic monitoring prior to and during antipsychotic drug use.
Appendix
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Metadata
Title
Applicability of somatic monitoring instructions in clinical practice guidelines on antipsychotic drug use
Authors
Jurriaan M. J. L. Brouwer
Erien Olde Hengel
Arne J. Risselada
Eric N. van Roon
Hans Mulder
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2021
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-021-03162-w

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