Published in:
01-12-2021 | Autism Spectrum Disorder | Research article
Predicting diagnostic outcome in adult autism spectrum disorder using the autism diagnostic observation schedule, second edition
Authors:
Marios Adamou, Sarah L. Jones, Stephanie Wetherhill
Published in:
BMC Psychiatry
|
Issue 1/2021
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Abstract
Background
The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) module four assessment for diagnosing autism spectrum disorder in adults has shown good sensitivity and specificity in research settings.
Method
This study aimed to evaluate the predictive accuracy of the ADOS-2 module four by investigating the components of the assessment, in relation to diagnostic outcome in a clinical setting. Data from 88 service users referred to a Specialist Adult Autism Service was explored.
Results
ADOS-2 scores failed to predict the diagnostic outcome (overall sensitivity = 92%, specificity = 57%). Interestingly, scores from the ‘restricted interests’ component of the ADOS-2 have the potential to predict diagnostic outcome, despite this domain not been included in the scoring algorithm.
Conclusions
Based on our findings, we recommend clinicians are cautious when interpreting results of the ADOS-2 assessment.