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Published in: BMC Psychiatry 1/2019

Open Access 01-12-2019 | Postpartum Depression | Research article

The effect of perceived social support during early pregnancy on depressive symptoms at 6 weeks postpartum: a prospective study

Authors: Yuexin Gan, Ran Xiong, Junjiao Song, Xinli Xiong, Fei Yu, Weiming Gao, Hui Hu, Jinsong Zhang, Ying Tian, Xiaobo Gu, Jun Zhang, Dan Chen

Published in: BMC Psychiatry | Issue 1/2019

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Abstract

Background

Postpartum depression was associated with maternal suffering and diminished functioning, increased risk of marital conflict as well as adverse child outcomes. Perceived social support during pregnancy was associated with postpartum depression among women. However, its causal relationship remains unclear. Therefore, we prospectively evaluate the association between perceived social support during early pregnancy and postpartum depressive symptoms.

Methods

We prospectively examined whether perceived social support during early pregnancy affected depressive symptoms at 6 weeks postpartum in a cohort of 3310 women. Perceived social support and postpartum depression were assessed by ENRICHD Social Support Instrument (ESSI) and the postpartum Edinburgh Postpartum Depression Scale (EPDS), respectively. Prevalence of postpartum depressive symptoms was 11.4% (EPDS cutoff≥10). As a test of heterogeneity of association in subpopulations, logistic regression models were performed to analyze the association between social support and postpartum depressive symptoms in strata which were defined by the potential confounder candidates. After multiple imputation, multivariable logistic regression was performed to assess the effect of social support on postpartum symptoms in individual items and total score. Two models were built. Model I adjusted for the variables associated with social support or postpartum depression and changed the association estimates by ≥10%. Model II adjusted for all variables that may be related to social support or postpartum depression.

Results

Significant associations between low perceived social support and postpartum depressive symptoms was found(Model I odds ratio: 1.63, 95% confidence interval: 1.15, 2.30; Model II odds ratio: 1.77, 95% confidence interval: 1.24–2.52). Stratified analyses showed that there was little evidence of heterogeneity of association in subpopulations by basic characteristics of participants.

Conclusions

These findings suggest that early intervention may be able to help protect against depression symptoms at 6 weeks postpartum.
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Metadata
Title
The effect of perceived social support during early pregnancy on depressive symptoms at 6 weeks postpartum: a prospective study
Authors
Yuexin Gan
Ran Xiong
Junjiao Song
Xinli Xiong
Fei Yu
Weiming Gao
Hui Hu
Jinsong Zhang
Ying Tian
Xiaobo Gu
Jun Zhang
Dan Chen
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2019
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-019-2188-2

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