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Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

Autism Spectrum disorders (ASD) in South Asia: a systematic review

Authors: Mohammad Didar Hossain, Helal Uddin Ahmed, M M Jalal Uddin, Waziul Alam Chowdhury, Mohd S Iqbal, Razin Iqbal Kabir, Imran Ahmed Chowdhury, Afzal Aftab, Pran Gopal Datta, Golam Rabbani, Saima Wazed Hossain, Malabika Sarker

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Autism spectrum disorders (ASD) are a group of complex neurodevelopmental disorders. The prevalence of ASD in many South Asian countries is still unknown. The aim of this study was to systematically review available epidemiological studies of ASD in this region to identify gaps in our current knowledge.

Methods

We searched, collected and evaluated articles published between January 1962 and July 2016 which reported the prevalence of ASD in eight South Asian countries. The search was conducted in line with the PRISMA guidelines.

Results

We identified six articles from Bangladesh, India, and Sri Lanka which met our predefined inclusion criteria. The reported prevalence of ASD in South Asia ranged from 0.09% in India to 1.07% in Sri Lanka that indicates up to one in 93 children have ASD in this region. Alarmingly high prevalence (3%) was reported in Dhaka city. Study sample sizes ranged from 374 in Sri Lanka to 18,480 in India. The age range varied between 1 and 30 years. No studies were found which reported the prevalence of ASD in Pakistan, Nepal, Bhutan, Maldives and Afghanistan. This review identifies methodological differences in case definition, screening instruments and diagnostic criteria among reported three countries which make it very difficult to compare the studies.

Conclusions

Our study is an attempt at understanding the scale of the problem and scarcity of information regarding ASD in the South Asia. This study will contribute to the evidence base needed to design further research and make policy decisions on addressing this issue in this region. Knowing the prevalence of ASD in South Asia is vital to ensure the effective allocation of resources and services.
Literature
1.
go back to reference American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Washington DC: American Psychiatric Association; 1994. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Washington DC: American Psychiatric Association; 1994.
2.
go back to reference Developmental Disabilities Monitoring Network Surveillance Year and Principal Investigators. Prevalence of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2010. Morb Mortal Wkly Rep Surveill Summ. 2014;63(2):1–21. http://www.cdc.gov/mmwr/pdf/ss/ss6302.pdf Developmental Disabilities Monitoring Network Surveillance Year and Principal Investigators. Prevalence of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2010. Morb Mortal Wkly Rep Surveill Summ. 2014;63(2):1–21. http://​www.​cdc.​gov/​mmwr/​pdf/​ss/​ss6302.​pdf
5.
go back to reference Elsabbagh M, Divan G, Koh YJ, Kim YS, Kauchali S, Marcín C, Montiel-Nava C, Patel V, Paula CS, Wang C, Yasamy MT, Fombonne E. Global prevalence of autism and other pervasive developmental disorders. Autism Res. 2012;5(3):160–79. doi:10.1002/aur.239.PubMedPubMedCentralCrossRef Elsabbagh M, Divan G, Koh YJ, Kim YS, Kauchali S, Marcín C, Montiel-Nava C, Patel V, Paula CS, Wang C, Yasamy MT, Fombonne E. Global prevalence of autism and other pervasive developmental disorders. Autism Res. 2012;5(3):160–79. doi:10.​1002/​aur.​239.PubMedPubMedCentralCrossRef
10.
go back to reference World Health Organization. International statistical classification of diseases and related health problems: tenth revision: World Health Organization (WHO); 1992. World Health Organization. International statistical classification of diseases and related health problems: tenth revision: World Health Organization (WHO); 1992.
13.
go back to reference Bassa DM. A case of early infantile autism. Indian J Psychiatry. 1962;4:73–6. Bassa DM. A case of early infantile autism. Indian J Psychiatry. 1962;4:73–6.
14.
go back to reference Poovathinal SA, Anitha A, Thomas R, Kaniamattam M, Melempatt N, Anilkumar A, Meena M. Prevalence of autism spectrum disorders in a semiurban community in south India. Ann Epidemiol. 2016;26(9):663–5. e668PubMedCrossRef Poovathinal SA, Anitha A, Thomas R, Kaniamattam M, Melempatt N, Anilkumar A, Meena M. Prevalence of autism spectrum disorders in a semiurban community in south India. Ann Epidemiol. 2016;26(9):663–5. e668PubMedCrossRef
15.
go back to reference Vandenbroucke JP, von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, Poole C, Schlesselman JJ, Egger M, STROBE Initiative. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007;147(8):W-163–94. doi:10.7326/0003-4819-147-8-200710160-00010-w1.CrossRef Vandenbroucke JP, von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, Poole C, Schlesselman JJ, Egger M, STROBE Initiative. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007;147(8):W-163–94. doi:10.​7326/​0003-4819-147-8-200710160-00010-w1.CrossRef
17.
go back to reference Rabbani MG, Alam MF, Ahmed HU, Sarkar M, Islam MS, Anwar N, Zaman MM, Chowdhury S, Chowdhury MWA, Hamid MA DSK, Islam MT, Mohit MA, Jahan NA, AHM MR, Chowdhury S, Chowdhury KP, Wahab MA, Rahman F, Mandal MC, Hossain MD, Bhowmik AD, Bashar MK, Khan NM, Uddin MJ, MZR K. Prevalence of mental disorders, mental retardation, epilepsy and substance abuse in children. Bangladesh J Psychiatry. 2009;23(1):1–54. Rabbani MG, Alam MF, Ahmed HU, Sarkar M, Islam MS, Anwar N, Zaman MM, Chowdhury S, Chowdhury MWA, Hamid MA DSK, Islam MT, Mohit MA, Jahan NA, AHM MR, Chowdhury S, Chowdhury KP, Wahab MA, Rahman F, Mandal MC, Hossain MD, Bhowmik AD, Bashar MK, Khan NM, Uddin MJ, MZR K. Prevalence of mental disorders, mental retardation, epilepsy and substance abuse in children. Bangladesh J Psychiatry. 2009;23(1):1–54.
18.
go back to reference NCDC, RCHCIB, BMRC, DSH. Survey of Autism and Neurodevelopmental Disorders in Bangladesh, 2013. Non Communicable Diseases Control (NCDC) Programme, DGHS, MOHFW, Revitalization of Community Health Care Initiatives in Bangladesh (RCHCIB), Ministry of health and family welfare (MOHFW); Bangladesh Medical Research Council (BMRC), MOHFW; Department of Pediatric Neuroscience, Dhaka Shishu Hospital, Dhaka, Bangladesh., 2013. NCDC, RCHCIB, BMRC, DSH. Survey of Autism and Neurodevelopmental Disorders in Bangladesh, 2013. Non Communicable Diseases Control (NCDC) Programme, DGHS, MOHFW, Revitalization of Community Health Care Initiatives in Bangladesh (RCHCIB), Ministry of health and family welfare (MOHFW); Bangladesh Medical Research Council (BMRC), MOHFW; Department of Pediatric Neuroscience, Dhaka Shishu Hospital, Dhaka, Bangladesh., 2013.
23.
go back to reference Alam DS, Robinson H, Kanungo A, Hossain MD, Hassan M. Health Systems Preparedness for responding to the growing burden of non-communicable disease-a case study of Bangladesh (Working Paper No 25). The Nossal Institute for Global Health, The University of Melbourne, AusAID Knowledge Hub for Health. 2013. Alam DS, Robinson H, Kanungo A, Hossain MD, Hassan M. Health Systems Preparedness for responding to the growing burden of non-communicable disease-a case study of Bangladesh (Working Paper No 25). The Nossal Institute for Global Health, The University of Melbourne, AusAID Knowledge Hub for Health. 2013.
28.
go back to reference Singhi P, Malhi P. Clinical and neurodevelopmental profile of young children with autism. Indian Pediatr. 2001;38(4):384–90.PubMed Singhi P, Malhi P. Clinical and neurodevelopmental profile of young children with autism. Indian Pediatr. 2001;38(4):384–90.PubMed
30.
go back to reference Vakil S, Welton E, Khanna R. Special education in India. Teach Except Child. 2002;34(5):46.CrossRef Vakil S, Welton E, Khanna R. Special education in India. Teach Except Child. 2002;34(5):46.CrossRef
34.
go back to reference Silberberg D, Arora N, Bhutani V, Durkin M, Gulati S, Nair M, Pinto-Martin J. Neuro-developmental disorders in India-from epidemiology to public policy (I10-1.006). Neurology. 2014;82(10 Supplement):I10-1. Silberberg D, Arora N, Bhutani V, Durkin M, Gulati S, Nair M, Pinto-Martin J. Neuro-developmental disorders in India-from epidemiology to public policy (I10-1.006). Neurology. 2014;82(10 Supplement):I10-1.
35.
go back to reference Zaman SS, Khan NZ, Islam S, Banu S, Dixit S, Shrout P, Durkin M. Validity of the ‘ten questions’ for screening serious childhood disability: results from urban Bangladesh. Int J Epidemiol. 1990;19(3):613–20. doi:10.1093/ije/19.3.613.PubMedCrossRef Zaman SS, Khan NZ, Islam S, Banu S, Dixit S, Shrout P, Durkin M. Validity of the ‘ten questions’ for screening serious childhood disability: results from urban Bangladesh. Int J Epidemiol. 1990;19(3):613–20. doi:10.​1093/​ije/​19.​3.​613.PubMedCrossRef
40.
45.
go back to reference Mishra N, Belbase M, Shrestha D, Poudel R, Mishra P. Childhood neurological illness in Nepal. J Nepal Health Res Counc. 2010;8(1):55–62.PubMed Mishra N, Belbase M, Shrestha D, Poudel R, Mishra P. Childhood neurological illness in Nepal. J Nepal Health Res Counc. 2010;8(1):55–62.PubMed
46.
go back to reference Nepal Government. National Policy and plan of action on disability Ministry for Women. Kathmandu Nepal: Children and Social Welfare Singha Durbar; 2006. Nepal Government. National Policy and plan of action on disability Ministry for Women. Kathmandu Nepal: Children and Social Welfare Singha Durbar; 2006.
Metadata
Title
Autism Spectrum disorders (ASD) in South Asia: a systematic review
Authors
Mohammad Didar Hossain
Helal Uddin Ahmed
M M Jalal Uddin
Waziul Alam Chowdhury
Mohd S Iqbal
Razin Iqbal Kabir
Imran Ahmed Chowdhury
Afzal Aftab
Pran Gopal Datta
Golam Rabbani
Saima Wazed Hossain
Malabika Sarker
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1440-x

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