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Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Study protocol

Working memory training in children with neuropsychiatric disorders and mild to borderline intellectual functioning, the role of coaching; a double-blind randomized controlled trial

Authors: Sammy Roording-Ragetlie, Helen Klip, Jan Buitelaar, Dorine Slaats-Willemse

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Working memory training (WMT) has been shown to offer therapeutic benefits to both patients with Attention-Deficit Hyperactivity Disorder (ADHD) and patients with mild to borderline Intellectual Disabilities (MBID; 60 < IQ < 85). However, robust evidence for transfer effects and treatment benefits of WMT over placebo training are lacking. Owing to the nature of double-blind research designs in RCTs, children have received non-specific coaching not based on their actual training performance. Active coaching based on individual training results (such as in clinical practice) might enhance the efficacy of Cogmed WMT. Furthermore, clinical experience and the general treatment approach to these vulnerable children has shown that the intensity and duration of WMT is often too stressful. This study therefore investigated the efficacy of a less intensive, but more prolonged Cogmed WMT (including active personalized coaching and feedback) in reducing behavioral symptoms and improving neurocognitive functioning and academic achievements in children with MBID and neuropsychiatric disorders.

Methods/design

A double-blind RCT with children (age 10.0–13.11) with neuropsychiatric disorders (ADHD and/or autism spectrum disorder (ASD)) and MBID (IQ: 60 < IQ < 85). Two groups (each n = 26) will receive Cogmed WMT (version R/M) at home or at school for 8 weeks, 4 days a week, at 30 min a day. One group will receive active personalized coaching and feedback based on their actual individual performance during Cogmed training. The other group will only receive general non-personalized coaching (i.e. no receive personalized coaching and feedback). Both groups will undergo a neurocognitive assessment (working memory, executive functioning, academic achievements) before and after training and complete several questionnaires (behavioral problems, parenting style) with a 6 months follow-up.

Discussion

This study will add to the literature since the role of coaching in Cogmed WMT has not been studied before. It will also provide opportunities to investigate an alternative version of WMT in a large group of vulnerable children, for whom few evidence-based treatments are available. Ultimately, this will allow us to advise mental health care professionals and special education schools about the use of this type of intervention for children with MBID and neuropsychiatric disorders.

Trial registration

Dutch Trial Register. NTR5223. Registration date 06–09-2015.
Literature
1.
go back to reference Strømme P, Diseth TH. Prevalence of psychiatric diagnoses in children with mental retardation: data from a population-based study. Dev Med Child Neurol. 2000:266–70. Strømme P, Diseth TH. Prevalence of psychiatric diagnoses in children with mental retardation: data from a population-based study. Dev Med Child Neurol. 2000:266–70.
2.
go back to reference Shinaver CS, Entwistle PC, Söderqvist S. Cogmed WM training: reviewing the reviews. Appl Neuropsychol Child. 2014;3:163–72.CrossRefPubMed Shinaver CS, Entwistle PC, Söderqvist S. Cogmed WM training: reviewing the reviews. Appl Neuropsychol Child. 2014;3:163–72.CrossRefPubMed
3.
go back to reference Chacko A, Feirsen N, Bedard AC, Marks D, Uderman JZ, Chimiklis A. Cogmed working memory training for youth with ADHD: a closer examination of efficacy utilizing evidence-based criteria. J Clin Child Adolesc Psychol. 2013;0:1–15. Chacko A, Feirsen N, Bedard AC, Marks D, Uderman JZ, Chimiklis A. Cogmed working memory training for youth with ADHD: a closer examination of efficacy utilizing evidence-based criteria. J Clin Child Adolesc Psychol. 2013;0:1–15.
4.
go back to reference Söderqvist S, Nutley SB, Ottersen J, Grill KM, Klingberg T. Computerized training of non-verbal reasoning and working memory in children with intellectual disability. Front Hum Neurosci. 2012;6:1–8.CrossRef Söderqvist S, Nutley SB, Ottersen J, Grill KM, Klingberg T. Computerized training of non-verbal reasoning and working memory in children with intellectual disability. Front Hum Neurosci. 2012;6:1–8.CrossRef
5.
go back to reference Van der Molen MJ, Van Luit JEH, Van der Molen MW, Klugkist I, Jongmans MJ. Effectiveness of a computerized working memory training in children with mild intellectual disabilities. J Intellect Disabil Res. 2010;54:433–47.CrossRefPubMed Van der Molen MJ, Van Luit JEH, Van der Molen MW, Klugkist I, Jongmans MJ. Effectiveness of a computerized working memory training in children with mild intellectual disabilities. J Intellect Disabil Res. 2010;54:433–47.CrossRefPubMed
6.
go back to reference Danielsson H, Zottarel V, Palmqvist L, Lanfranchi S. The effectiveness of working memory training with individuals with intellectual disabilities – a meta-analytic review. Front Psychol. 2015;6:1–10.CrossRef Danielsson H, Zottarel V, Palmqvist L, Lanfranchi S. The effectiveness of working memory training with individuals with intellectual disabilities – a meta-analytic review. Front Psychol. 2015;6:1–10.CrossRef
7.
go back to reference Hodgson K, Hutchinson AD, Denson L. Nonpharmacological treatments for ADHD. A meta-analytic review. J Atten Disorders. 2014;18:275–82.CrossRef Hodgson K, Hutchinson AD, Denson L. Nonpharmacological treatments for ADHD. A meta-analytic review. J Atten Disorders. 2014;18:275–82.CrossRef
8.
go back to reference Sonuga-Barke EJS, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M, et al. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry. 2013;170:275–89.CrossRefPubMed Sonuga-Barke EJS, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M, et al. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry. 2013;170:275–89.CrossRefPubMed
9.
go back to reference Rapport MD, Orban SA, Kofler MJ, Friedman LM. Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta-analytic review of cognitive, academic, and behavioural outcomes. Clin Psychol Rev. 2013;33:1237–52.CrossRefPubMed Rapport MD, Orban SA, Kofler MJ, Friedman LM. Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta-analytic review of cognitive, academic, and behavioural outcomes. Clin Psychol Rev. 2013;33:1237–52.CrossRefPubMed
10.
go back to reference Van Dongen-Boomsma M, Vollebregt MA, Buitelaar JK, Slaats-Willemse D. Working memory training in young children with ADHD: a randomized placebo-controlled trial. J Clin Child Adolesc Psychol. 2014;55:886–96. Van Dongen-Boomsma M, Vollebregt MA, Buitelaar JK, Slaats-Willemse D. Working memory training in young children with ADHD: a randomized placebo-controlled trial. J Clin Child Adolesc Psychol. 2014;55:886–96.
11.
go back to reference Mawjee K, Woltering S, Lai N, Gotlieb H, Kronitz R, Tannock R. Working memory training in ADHD: controlling for engagement, motivation, and expectancy of improvement (pilot study). J Atten Disorders. 2014:1–13. doi:10.1177/1087054714557356. Mawjee K, Woltering S, Lai N, Gotlieb H, Kronitz R, Tannock R. Working memory training in ADHD: controlling for engagement, motivation, and expectancy of improvement (pilot study). J Atten Disorders. 2014:1–13. doi:10.​1177/​1087054714557356​.
12.
go back to reference Richtlijn Effectieve Interventies LVB. Utrecht: Landelijk Kenniscentrum LVG; 2011. Richtlijn Effectieve Interventies LVB. Utrecht: Landelijk Kenniscentrum LVG; 2011.
13.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association Press; 2000. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association Press; 2000.
14.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association Press; 2013.CrossRef American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association Press; 2013.CrossRef
15.
go back to reference Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH diagnostic interview schedule for children version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry. 2000;39:28–38.CrossRefPubMed Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH diagnostic interview schedule for children version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry. 2000;39:28–38.CrossRefPubMed
16.
go back to reference Berument SK, Rutter M, Lord C, Pickles A, Bailey A. Autism screening questionnaire: diagnostic validity. Br J Psychiatry. 1999;175:444–51.CrossRefPubMed Berument SK, Rutter M, Lord C, Pickles A, Bailey A. Autism screening questionnaire: diagnostic validity. Br J Psychiatry. 1999;175:444–51.CrossRefPubMed
17.
go back to reference Kort W, Schittekatte M, Bosmans M, Compaan EL, Dekker PH, Vermeir G, Verhaeghe P. Wechsler intelligence scale for children-III Nederlandse uitgave [WISC-III-NL]. Amsterdam: Harcourt Test Publishers; 2005. Kort W, Schittekatte M, Bosmans M, Compaan EL, Dekker PH, Vermeir G, Verhaeghe P. Wechsler intelligence scale for children-III Nederlandse uitgave [WISC-III-NL]. Amsterdam: Harcourt Test Publishers; 2005.
18.
go back to reference Alloway TP. Automated working memory assessment. London: Harcourt Assessment; 2007. Alloway TP. Automated working memory assessment. London: Harcourt Assessment; 2007.
19.
go back to reference Pickering SJ, Gathercole SE. Working memory test battery for children. Londen: Psychological Corporation; 2001. Pickering SJ, Gathercole SE. Working memory test battery for children. Londen: Psychological Corporation; 2001.
20.
go back to reference De Sonneville L. Amsterdamse Neuropsychologische Taken [ANT]. Amsterdam: Boom Testuitgevers; 2009. De Sonneville L. Amsterdamse Neuropsychologische Taken [ANT]. Amsterdam: Boom Testuitgevers; 2009.
21.
go back to reference Zijlstra HP, Kingma A, Swaab H, Brouwer WH. Nepsy-II-nl. Enschede: Ipskamp; 2010. Zijlstra HP, Kingma A, Swaab H, Brouwer WH. Nepsy-II-nl. Enschede: Ipskamp; 2010.
22.
go back to reference Brus BT, Voeten MJM. Eén minuut test. Nijmegen: Berkhout; 1973. Brus BT, Voeten MJM. Eén minuut test. Nijmegen: Berkhout; 1973.
23.
go back to reference De Vos T. Tempo Test Rekenen. Lisse: Swets Test Publishers; 1992. De Vos T. Tempo Test Rekenen. Lisse: Swets Test Publishers; 1992.
24.
go back to reference Frick PJ. The Alabama parenting questionnaire: University of Alabama; 1991. Frick PJ. The Alabama parenting questionnaire: University of Alabama; 1991.
25.
go back to reference Luteijn E, Minderaa R, Jackson S. Vragenlijst voor Inventarisatie van Sociaal gedrag Kinderen [VISK]. Amsterdam: Pearson Assessment and Information B.V; 2002. Luteijn E, Minderaa R, Jackson S. Vragenlijst voor Inventarisatie van Sociaal gedrag Kinderen [VISK]. Amsterdam: Pearson Assessment and Information B.V; 2002.
26.
go back to reference Scholte EM, Van der Ploeg JD. AVL ADHD-vragenlijst. Houten: Bohn Stafleu van Loghum; 2005. Scholte EM, Van der Ploeg JD. AVL ADHD-vragenlijst. Houten: Bohn Stafleu van Loghum; 2005.
27.
go back to reference Smidts D, Huizinga M. Executieve Functies Gedragsvragenlijst [BRIEF]. Amsterdam: Hogrefe Uitgevers; 2009. Smidts D, Huizinga M. Executieve Functies Gedragsvragenlijst [BRIEF]. Amsterdam: Hogrefe Uitgevers; 2009.
28.
go back to reference Fuchs D, Fuchs LS. Test procedure bias: a meta-analysis of examiner familiarity effects. Rev Educ Res. 1986;56:243–62.CrossRef Fuchs D, Fuchs LS. Test procedure bias: a meta-analysis of examiner familiarity effects. Rev Educ Res. 1986;56:243–62.CrossRef
29.
Metadata
Title
Working memory training in children with neuropsychiatric disorders and mild to borderline intellectual functioning, the role of coaching; a double-blind randomized controlled trial
Authors
Sammy Roording-Ragetlie
Helen Klip
Jan Buitelaar
Dorine Slaats-Willemse
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1274-6

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