Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
BMC Psychiatry
Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey

Authors: Seulki Lee, Aesun Shin

Published in: BMC Psychiatry | Issue 1/2017

Login to get access

Abstract

Background

Atopic dermatitis (AD) is a chronic skin disease which has been known to negatively influence the mental health of patients. However, only a few studies have explored the prevalence of psychiatric problems among AD patients, particularly among adolescents. In this study, we aimed to assess the association of AD with depressive symptoms and suicidal behaviors among adolescents by analyzing data from the 2013 Korean Youth Risk Behavior Survey, a nationwide web-based survey.

Methods

Data from 72,435 adolescent middle and high school students in Korea were analyzed. Students self-reported AD diagnosed by a doctor and yes-or-no answers to questions about depressive symptoms and suicide ideation, suicide planning, and suicide attempts were analyzed. Relationships between AD and depressive symptoms or suicidal behaviors were tested by logistic regression models after controlling for potential confounding factors.

Results

The proportion of adolescents who had AD was 6.8%. The proportion of adolescents reporting depressive feelings was 31.0%, suicide ideation was 16.3%, suicide planning was 5.8%, and suicide attempts was 4.2%. Compared to adolescents without AD, adolescents with AD were significantly more likely to experience depressive feelings (odds ratio [OR]: 1.27, 95% confidence interval [Cl]: 1.19-1.36), suicide ideation (OR: 1.34, 95% Cl: 1.24-1.45), suicide planning (OR: 1.46, 95% Cl: 1.32-1.65), and suicide attempts (OR: 1.51, 95% Cl: 1.33-1.72). In the multivariate model, the relationships between AD and suicide ideation (OR: 1.26, 95% Cl:1.16-1.36), suicide planning (OR: 1.28, 95% Cl:1.14-1.44), and suicide attempt (OR: 1.29, 95% Cl:1.13-1.49) were statistically significant.

Conclusion

Adolescents who have AD are associated with a higher prevalence of depression symptoms and suicidal behaviors. Adolescent AD patients may need interventions from clinicians and caregivers that use a holistic approach to prevent psychological comorbidities, although further research is needed to clarify this relationship.
Literature
1.
Habif TP. Clinical Dermatology: a color guide to diagnosis and therapy, 5th edn. London: Elsevier Health Sciences; 2009.
2.
3.
Kim K. Current status and characteristics of atopic dermatitis in Korea. J Korean Medical Assoc. 2014;57(3):208–11.CrossRef
4.
Korea Youth Risk Behavior Web-based Survey. The Ninth Korea Youth Risk Behavior Web-based Survey 2012. In. Edited by Ministry of Education, Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Youth Risk Behavior Web-based Survey; 2012.
5.
Carson CG. Risk factors for developing atopic dermatitis. Dan Med J. 2013;60(7):B4687.PubMed
6.
Mercer MJ, Joubert G, Ehrlich RI, Nelson H, Poyser MA, Puterman A, Weinberg EG. Socioeconomic status and prevalence of allergic rhinitis and atopic eczema symptoms in young adolescents. Pediatr Allergy Immunol. 2004;15(3):234–41.CrossRefPubMed
7.
Bodner C, Godden D, Seaton A. Family size, childhood infections and atopic diseases. Aberdeen WHEASE Group Thorax. 1998;53(1):28–32.PubMed
8.
Bråbäck L, Kälvesten L. Urban living as a risk factor for atopic sensitization in Swedish schoolchildren. Pediatr Allergy Immunol. 1991;2(1):14–9.CrossRef
9.
Absolon CM, Cottrell D, Eldridge SM, Glover MT. Psychological disturbance in atopic eczema: the extent of the problem in school-aged children. Br J Dermatol. 1997;137(2):241–5.CrossRefPubMed
10.
Lewis-Jones S. Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema. Int J Clin Pract. 2006;60(8):984–92.CrossRefPubMed
11.
Hashiro M, Okumura M. Anxiety, depression, psychosomatic symptoms and autonomic nervous function in patients with chronic urticaria. J Dermatol Sci. 1994;8(2):129–35.CrossRefPubMed
12.
Gupta MA, Gupta AK. Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. Br J Dermatol. 1998;139(5):846–50.CrossRefPubMed
13.
Sanna L, Stuart AL, Pasco JA, Jacka FN, Berk M, Maes M, O'Neil A, Girardi P, Williams LJ. Atopic disorders and depression: findings from a large, population-based study. J Affect Disord. 2014;155:261–5.CrossRefPubMed
14.
Timonen M, Jokelainen J, Hakko H, Silvennoinen-Kassinen S, Meyer-Rochow VB, Herva A, Rasanen P. Atopy and depression: results from the Northern Finland 1966 Birth Cohort Study. Mol Psychiatry. 2003;8(8):738–44.CrossRefPubMed
15.
Klokk M, Gotestam KG, Mykletun A. Factors accounting for the association between anxiety and depression, and eczema: the Hordaland health study (HUSK). BMC Dermatol. 2010;10:3.CrossRefPubMedPubMedCentral
16.
Yaghmaie P, Koudelka CW, Simpson EL. Mental health comorbidity in patients with atopic dermatitis. J Allergy Clin Immunol. 2013;131(2):428–33.CrossRefPubMed
17.
18.
Andersen SL, Teicher MH. Stress, sensitive periods and maturational events in adolescent depression. Trends Neurosci. 2008;31(4):183–91.CrossRefPubMed
19.
Andersen SL. Trajectories of brain development: point of vulnerability or window of opportunity? Neurosci Biobehav Rev. 2003;27(1-2):3–18.CrossRefPubMed
20.
Kim HS, Kim HS. Risk factors for suicide attempts among Korean adolescents. Child Psychiatry Hum Dev. 2008;39(3):221–35.CrossRefPubMed
21.
Brent DA, Perper JA, Moritz G, Allman C, Friend A, Roth C, Schweers J, Balach L, Baugher M. Psychiatric risk factors for adolescent suicide: a case-control study. J Am Acad Child Adolesc Psychiatry. 1993;32(3):521–9.CrossRefPubMed
22.
Nock MK, Hwang I, Sampson N, Kessler RC, Angermeyer M, Beautrais A, Borges G, Bromet E, Bruffaerts R, de Girolamo G, et al. Cross-national analysis of the associations among mental disorders and suicidal behavior: findings from the WHO World Mental Health Surveys. PLoS Med. 2009;6(8):e1000123.CrossRefPubMedPubMedCentral
23.
Korean Centers for Disease Control and Prevention. Korea Health Statistics 2012: Korean National Health and Nutrition Examination Survey (KNHANES V-3). In. Edited by Ministry of Health and Welfare: Korean Centers for Disease Control and Prevention. 2012;161.
24.
Jin J, Go H. The Korean suicide rate trend by population group comparing with the OECD countries and its policy implications. In: Health and Welfare Policy Forum: 2013;2013:141–54.
25.
Noh H-M, Cho JJ, Park YS, Kim J-H. The relationship between suicidal behaviors and atopic dermatitis in Korean adolescents. J Health Psychol. 2015;1359105315572453.
26.
Korea Youth Risk Behavior Web-based Survey. The Ninth Korea Youth Risk Behavior Web-based Survey 2013. In. Edited by Ministry of Education, Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Youth Risk Behavior Web-based Survey; 2013.
27.
Lehtinen V, Joukamaa M. Epidemiology of depression: prevalence, risk factors and treatment situation. Acta Psychiatr Scand Suppl. 1994;377:7–10.CrossRefPubMed
28.
Beekman A, Copeland J, Prince MJ. Review of community prevalence of depression in later life. Br J Psychiatry. 1999;174(4):307–11.CrossRefPubMed
29.
Goodman E, Slap GB, Huang B. The public health impact of socioeconomic status on adolescent depression and obesity. Am J Public Health. 2003;93(11):1844–50.CrossRefPubMedPubMedCentral
30.
Adrien J. Neurobiological bases for the relation between sleep and depression. Sleep Med Rev. 2002;6(5):341–51.CrossRefPubMed
31.
Flannery DJ, Wester KL, Singer MI. Impact of exposure to violence in school on child and adolescent mental health and behavior. J Community Psychol. 2004;32(5):559–73.CrossRef
32.
Lewis-Jones MS, Finlay AY. The Children's Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol. 1995;132(6):942–9.CrossRefPubMed
33.
Fergusson DM, Boden JM, Horwood LJ. Tests of causal links between alcohol abuse or dependence and major depression. Arch Gen Psychiatry. 2009;66(3):260–6.CrossRefPubMed
34.
Vally H, Thompson PJ. Alcoholic drink consumption: a role in the development of allergic disease? Clin Exp Allergy. 2003;33(2):156–8.CrossRefPubMed
35.
Lucas M, Mekary R, Pan A, Mirzaei F, O'Reilly EJ, Willett WC, Koenen K, Okereke OI, Ascherio A. Relation between clinical depression risk and physical activity and time spent watching television in older women: a 10-year prospective follow-up study. Am J Epidemiol. 2011;174(9):1017–27.CrossRefPubMedPubMedCentral
36.
Pasco JA, Williams LJ, Jacka FN, Ng F, Henry MJ, Nicholson GC, Kotowicz MA, Berk M. Tobacco smoking as a risk factor for major depressive disorder: population-based study. Br J Psychiatry. 2008;193(4):322–6.CrossRefPubMed
37.
The guideline for users. KYRBS 2013. In. Edited by Ministry of Education, Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Centers for Disease Control and Prevention; 2013.
38.
World Health Organization: Inequalities in Young People's Health: Health Behaviour in School-aged Children (HBSC) International Report from the 2005/2006 Survey. Geneva: World Health Organization. 2008;14.
39.
Dunn AL, Trivedi MH, Kampert JB, Clark CG, Chambliss HO. Exercise treatment for depression: efficacy and dose response. Am J Prev Med. 2005;28(1):1–8.CrossRefPubMed
40.
Hong S, Son DK, Lim WR, Kim SH, Kim H, Yum HY, Kwon H. The prevalence of atopic dermatitis, asthma, and allergic rhinitis and the comorbidity of allergic diseases in children. Environ Health Toxicol. 2012;27:e2012006.CrossRefPubMedPubMedCentral
41.
Williams HC, Strachan DP. The natural history of childhood eczema: observations from the British 1958 birth cohort study. Br J Dermatol. 1998;139(5):834–9.CrossRefPubMed
42.
Illi S, von Mutius E, Lau S, Nickel R, Gruber C, Niggemann B, Wahn U, Multicenter Allergy Study G. The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol. 2004;113(5):925–31.CrossRefPubMed
43.
Ricci G, Patrizi A, Baldi E, Menna G, Tabanelli M, Masi M. Long-term follow-up of atopic dermatitis: retrospective analysis of related risk factors and association with concomitant allergic diseases. J Am Acad Dermatol. 2006;55(5):765–71.CrossRefPubMed
44.
Buske-Kirschbaum A, Geiben A, Hellhammer D. Psychobiological aspects of atopic dermatitis: an overview. Psychother Psychosom. 2001;70(1):6–16.CrossRefPubMed
45.
Wamboldt MZ, Hewitt JK, Schmitz S, Wamboldt FS, Rasanen M, Koskenvuo M, Romanov K, Varjonen J, Kaprio J. Familial association between allergic disorders and depression in adult Finnish twins. Am J Med Genet. 2000;96(2):146–53.CrossRefPubMed
46.
Slattery MJ, Essex MJ, Paletz EM, Vanness ER, Infante M, Rogers GM, Gern JE. Depression, anxiety, and dermatologic quality of life in adolescents with atopic dermatitis. J Allergy Clin Immunol. 2011;128(3):668–71.CrossRefPubMedPubMedCentral
47.
Evers AW, Lu Y, Duller P, van der Valk PG, Kraaimaat FW, van de Kerkhof PC. Common burden of chronic skin diseases? Contributors to psychological distress in adults with psoriasis and atopic dermatitis. Br J Dermatol. 2005;152(6):1275–81.CrossRefPubMed
48.
Kriegsman DM, Penninx BW, van Eijk JT, Boeke AJ, Deeg DJ. Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients' self-reports and on determinants of inaccuracy. J Clin Epidemiol. 1996;49(12):1407–17.CrossRefPubMed
49.
American Psychiatry Association. Diagnostic and Statistical Manual of Mental Disorders, 5th edition. In: Section II: Diagnostic Criteria and Codes, Depressive Disorders. Washington, DC. 2013;125.
50.
Park JH, Kim KW. A review of the epidemiology of depression in Korea. J Korean Med Assoc. 2001;28(1):1–8.
51.
Yoo SK, Skovholt TM. Cross-cultural examination of depression expression and help-seeking behavior: A comparative study of American and Korean college students. J Coll Couns. 2001;4(1):10–9.
52.
Hoagwood K, Olin SS. The NIMH blueprint for change report: research priorities in child and adolescent mental health. J Am Acad Child Adolesc Psychiatry. 2002;41(7):760–7.CrossRefPubMed
53.
Korea Statistics. The Statistics of Causes of Death in Korea, 2013. Korean Statistical Information Service: Statistics Korea; Daejeon, 2013.
54.
Meery Lee RL. The Korean ‘Examination Hell’: Long Hours of Studying, Distress, and Depression. J Youth Adolesc. 2000;29(2):249–71.CrossRef
55.
Lee M. Korean adolescents’ “examination hell” and their use of free time. New Dir Child Adolesc Dev. 2003;99:9–21.CrossRef
56.
Staab D, Diepgen TL, Fartasch M, Kupfer J, Lob-Corzilius T, Ring J, Scheewe S, Scheidt R, Schmid-Ott G, Schnopp C, et al. Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial. BMJ. 2006;332(7547):933–8.CrossRefPubMedPubMedCentral
57.
Ehlers A, Stangier U, Gieler U. Treatment of atopic dermatitis: a comparison of psychological and dermatological approaches to relapse prevention. J Consult Clin Psychol. 1995;63(4):624–35.CrossRefPubMed
Metadata
Title
Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey
Authors
Seulki Lee
Aesun Shin
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-016-1160-7

Other articles of this Issue 1/2017

BMC Psychiatry 1/2017 Go to the issue

Research article

Depression: point-prevalence and risk factors in a North Cyprus household adult cross-sectional study

Research article

Randomised controlled trial to improve health and reduce substance use in established psychosis (IMPaCT): cost-effectiveness of integrated psychosocial health promotion

Research article

Reliability and validity of general health questionnaire (GHQ-12) for male tannery workers: a study carried out in Kanpur, India

Research article

Feasibility and efficacy of shared decision making for first-admission schizophrenia: a randomized clinical trial

Case report

Antipsychotic-associated psoriatic rash – a case report

Study protocol

Rationale and design of the PLACID study: a randomised trial comparing the efficacy and safety of inhaled loxapine versus IM aripiprazole in acutely agitated patients with schizophrenia or bipolar disorder