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Published in: BMC Psychiatry 1/2015

Open Access 01-12-2015 | Research article

Prevalence and correlates of depression and anxiety among patients with tuberculosis at WolaitaSodo University Hospital and Sodo Health Center, WolaitaSodo, South Ethiopia, Cross sectional study

Authors: Bereket Duko, Abebaw Gebeyehu, Getnet Ayano

Published in: BMC Psychiatry | Issue 1/2015

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Abstract

Background

Anxiety and depression are frequently and highly occurring mental disorders in patients with tuberculosis. When depression and anxiety co-morbid with tuberculosis, it leads to poor adherence to anti TB medication, which is important barrier to global control of tuberculosis & increases the risk of morbidity and mortality due to TB. Cross sectional study was conducted to assess prevalence and correlates of depression and anxiety among patients with TB at WolaitaSodo University Hospital and Sodo Health Center, WolaitaSodo, Ethiopia.

Methods

Institution based cross-sectional study was conducted in 2014.A total of 417 TB patients, who had regular follow up at WolaitaSodo University Hospital and Sodo Health Center, WolaitaSodo, South Ethiopia, were recruited to assess depression and anxiety and its associated correlates. Depression and anxiety were assessed through face to face interviews by trained psychiatry nurses using the hospital anxiety and depression scale (HADS). Correlates for depression and anxiety were assessed using a structured questionnaire, Oslo social support scale and TB stigma Scale.

Results

The prevalence of depression and anxiety among patients with TB were 43.4 % (181) and 41.5 % (173) respectively. When we adjusted for the effect of potential confounding variables, patients who had co-morbid HIV infection [AOR = 5.90,(95 % CI: 2.34,15.93)], poor social support [AOR = 18.06, (95 % CI:11.21,25.45)] & perceived TB stigma [AOR = 10.86, (95 % CI:10.26,23.47)] were more likely to have depression as compared to individuals who had no co-morbid HIV infection, good social support and no perceived TB stigma respectively. Patients who had co-morbid HIV infection [AOR = 9.61,(95 % CI:3.56,25.96)], poor social support [AOR = 8.93,(95 % CI: 5.01,15.94)], perceived TB stigma [AOR = 3.11,(95 % CI:1.78,5.42)], being female [AOR = 1.72 (95 % CI: 1.06, 2.95)], current substance use[AOR = 4.88, (95 % CI: 1.79, 13.28)] and being on intensive phase of TB treatment [AOR = 1.91, (95 % CI: 1.08, 3.39)] were more likely to have anxiety as compared to individuals who had no co-morbid HIV infection, good social support, no perceived TB stigma, being male and being on continuous phase of TB treatment respectively.

Conclusion

Developing guidelines and training of health workers in TB clinics is useful to screen and treat depression and anxiety among TB patients.
Literature
2.
go back to reference Rajeswari R, Balasubramanian R, Muniyandi M, Geetharamani S, Thresa X. Socio-economic impact of tuberculosis on patients and family in India. Int J Tuberc Lung Dis. 2009;3:869–77. Rajeswari R, Balasubramanian R, Muniyandi M, Geetharamani S, Thresa X. Socio-economic impact of tuberculosis on patients and family in India. Int J Tuberc Lung Dis. 2009;3:869–77.
9.
go back to reference Kebede D, Alem A. Major Mental disorders in Addis Ababa. Ethiopia Acta Psychiatric Scand. 1999;100:18–23.CrossRef Kebede D, Alem A. Major Mental disorders in Addis Ababa. Ethiopia Acta Psychiatric Scand. 1999;100:18–23.CrossRef
10.
go back to reference Benjamin JS, V A. Kaplan & Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. Lippincott Williams & Wilkins. 2007;10th Edition,: p.582. Benjamin JS, V A. Kaplan & Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. Lippincott Williams & Wilkins. 2007;10th Edition,: p.582.
11.
go back to reference Husain MO, Dearman SP, Chaudhry IB, Rizvi N, Waheed W. the relationship between anxiety, depression and illness perception In tuberculosis patients in Pakistan. Clin Pract Epidemiol Mental Health. 2008;4(14):15. Husain MO, Dearman SP, Chaudhry IB, Rizvi N, Waheed W. the relationship between anxiety, depression and illness perception In tuberculosis patients in Pakistan. Clin Pract Epidemiol Mental Health. 2008;4(14):15.
12.
go back to reference Manmilena A, Octivluiza N, Cosmina B, Antigona T, Dana A. Depressive syndrome, anxiety and illness perception in Tuberculosis patients. Recent Res Mod Med. 2010;243–248. Manmilena A, Octivluiza N, Cosmina B, Antigona T, Dana A. Depressive syndrome, anxiety and illness perception in Tuberculosis patients. Recent Res Mod Med. 2010;243–248.
13.
go back to reference Georgios M, Athanasios T, Athanasios K, Dimitra S, Ioannis I, Dionisios B, et al. A, comparative study of anxiety and depression in patients with bronchial asthma, chronic obstructive pulmonary disease and tuberculosis in a general hospital of chest diseases. Ann Gen Psychiatry. 2008;7:7.CrossRef Georgios M, Athanasios T, Athanasios K, Dimitra S, Ioannis I, Dionisios B, et al. A, comparative study of anxiety and depression in patients with bronchial asthma, chronic obstructive pulmonary disease and tuberculosis in a general hospital of chest diseases. Ann Gen Psychiatry. 2008;7:7.CrossRef
14.
go back to reference Ige OM, Lasebikan VO. Prevalence of Depression in Tuberculosis Patients in Comparison to Non-Tuberculosis Family Contacts Visiting the DOTS clincs in Tertiary Care Hospital and its Correlation with Disease Pattern. J Mental Health FamMe. 2011;8(4):235–41. Ige OM, Lasebikan VO. Prevalence of Depression in Tuberculosis Patients in Comparison to Non-Tuberculosis Family Contacts Visiting the DOTS clincs in Tertiary Care Hospital and its Correlation with Disease Pattern. J Mental Health FamMe. 2011;8(4):235–41.
15.
go back to reference Micheline KN. Prevalence of depression among TB patients attending tuberculosis clinc at Mbagatji District Hospital Nairibi Kenya. Clin Psychol Dissert. 2011;6(15):15–23. Micheline KN. Prevalence of depression among TB patients attending tuberculosis clinc at Mbagatji District Hospital Nairibi Kenya. Clin Psychol Dissert. 2011;6(15):15–23.
16.
go back to reference Benjamin JS, Virgina As. synopsis of psychiatry text book 10th ed. Chap. Rihmer Z. Angest A. Mood disorder: epidemology in Sadock BJ Sadock VA, eds. Comprehensive text book of psychiatry 8th Baltimore Lippincott Willian and Wilikin. 2004;10th ed:p.529. Benjamin JS, Virgina As. synopsis of psychiatry text book 10th ed. Chap. Rihmer Z. Angest A. Mood disorder: epidemology in Sadock BJ Sadock VA, eds. Comprehensive text book of psychiatry 8th Baltimore Lippincott Willian and Wilikin. 2004;10th ed:p.529.
17.
go back to reference Morrison SD, Banushi VH, Sarnquist C, Gashi VH, Osterberg YM. Levels of self-reported depression and anxiety among HIV-positive patients in Albania,a cross-sectional study. Croat Med J. 2011;52(5):622–8.CrossRefPubMedPubMedCentral Morrison SD, Banushi VH, Sarnquist C, Gashi VH, Osterberg YM. Levels of self-reported depression and anxiety among HIV-positive patients in Albania,a cross-sectional study. Croat Med J. 2011;52(5):622–8.CrossRefPubMedPubMedCentral
18.
go back to reference Eva KH, Tijeerd BV, Benthem L, Hakkaart VR, Harm WJ, Van M, et al. Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general setting, a randmised controlled trial. J BMC Health Serv Res. 2007;7(28):1472–6963. Eva KH, Tijeerd BV, Benthem L, Hakkaart VR, Harm WJ, Van M, et al. Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general setting, a randmised controlled trial. J BMC Health Serv Res. 2007;7(28):1472–6963.
19.
go back to reference Dalgard OS,Dowrick C, Lehtinen V, Vazquez-Barquero JL, Casey P, Wilkinson G, et al. Negative life events, social support and gender difference in depression, social psyciatry and psychiatric epidemiology. 2006;41(6):444-51 Dalgard OS,Dowrick C, Lehtinen V, Vazquez-Barquero JL, Casey P, Wilkinson G, et al. Negative life events, social support and gender difference in depression, social psyciatry and psychiatric epidemiology. 2006;41(6):444-51
20.
go back to reference Van Rie A, Sengupta S, Pungrassami P, Balthip Q, Choonuan S, Kasetjaroen Y, et al. Measuring stigma associated with tuberculosis and HIV/AIDS in southern Thailand: exploratory and confirmatory factor analyses of two new scales. Trop Med Int Health. 2008;13(1):21–30. Van Rie A, Sengupta S, Pungrassami P, Balthip Q, Choonuan S, Kasetjaroen Y, et al. Measuring stigma associated with tuberculosis and HIV/AIDS in southern Thailand: exploratory and confirmatory factor analyses of two new scales. Trop Med Int Health. 2008;13(1):21–30.
21.
go back to reference Reda AA. Reliability and Validity of the Ethiopian Version of the Hospital Anxiety and Depression (HADS) in HIV Infected Patients. PLoS One. 2011;6(1):e16049. Reda AA. Reliability and Validity of the Ethiopian Version of the Hospital Anxiety and Depression (HADS) in HIV Infected Patients. PLoS One. 2011;6(1):e16049.
22.
go back to reference Aniebue PN, Okonkwo K. Prevalence of depression symptoms among Pulmonary Tuberculosis patients at the university of Nigeria Teaching Hospital, Enugu. J Col Med. 2006;11(2):120–4. Aniebue PN, Okonkwo K. Prevalence of depression symptoms among Pulmonary Tuberculosis patients at the university of Nigeria Teaching Hospital, Enugu. J Col Med. 2006;11(2):120–4.
23.
go back to reference Baba AI, Abdullah DY, Suleiman IK. Depression co-morbidity among patients with Tuberculosis in a university teaching hospital outpatient clinic in Nigeria. J Mental Health Fam Med. 2009;6(3):133–8. Baba AI, Abdullah DY, Suleiman IK. Depression co-morbidity among patients with Tuberculosis in a university teaching hospital outpatient clinic in Nigeria. J Mental Health Fam Med. 2009;6(3):133–8.
24.
go back to reference Basu G, Chatterjee C, Singh R, Biswas S. Prevalence of depression in tuberculosis patients: An experience from a DOTS clinic. IJRRMS. 2012; Vol 2 (4). Basu G, Chatterjee C, Singh R, Biswas S. Prevalence of depression in tuberculosis patients: An experience from a DOTS clinic. IJRRMS. 2012; Vol 2 (4).
25.
go back to reference Swarn LP. Correlation with duration and depression in TB patients in rural Jaipur District Hospital. Int J Pharm Bio Sci. 2011;2(2):263–7. Swarn LP. Correlation with duration and depression in TB patients in rural Jaipur District Hospital. Int J Pharm Bio Sci. 2011;2(2):263–7.
26.
go back to reference Deribew A, Tesfaye M, Hailmichael Y, Apers L, Abebe G, Duchateau L, et al. Common mental disorders in TB/HIV co-infected patients in Ethiopia. BMC Infect Dis Res Article. 2010;10:201. Deribew A, Tesfaye M, Hailmichael Y, Apers L, Abebe G, Duchateau L, et al. Common mental disorders in TB/HIV co-infected patients in Ethiopia. BMC Infect Dis Res Article. 2010;10:201.
27.
go back to reference Karl P, Pamela N, Gladys M, Julia L, Gugu M. Prevalence of psychological distress and correlates in tuberculosis patients in public primary care clinics in South Africa. BMC Psychiatry. 2012;12:89. Karl P, Pamela N, Gladys M, Julia L, Gugu M. Prevalence of psychological distress and correlates in tuberculosis patients in public primary care clinics in South Africa. BMC Psychiatry. 2012;12:89.
28.
go back to reference Li L, Lee SJ, Thammawijaya P, Jiraphongsa C, Rotheram-Borus MJ. Stigma,social support, and depression among people living with HIV in Thailand. AIDS Care. 2009;21(8):1007–13. Li L, Lee SJ, Thammawijaya P, Jiraphongsa C, Rotheram-Borus MJ. Stigma,social support, and depression among people living with HIV in Thailand. AIDS Care. 2009;21(8):1007–13.
29.
go back to reference Muhammad AS, Imtiaz AD, Hamza S, Zain M, Muhammad A, Obaid N. Prevalence of depression among Tuberculosis patients. J APMC. 2010;4(2):134–7. Muhammad AS, Imtiaz AD, Hamza S, Zain M, Muhammad A, Obaid N. Prevalence of depression among Tuberculosis patients. J APMC. 2010;4(2):134–7.
30.
go back to reference Perlick DA, Rosenheck RA, Clarkin JF, Sirey JA, Salahi J, Struening EL, et al. Stigma as a barrier to recovery: Adverse effects of perceived stigma on social adaptation of persons diagnosed `with bipolar affective disorder. Sychiatr Serv P. 2001;52:162. Perlick DA, Rosenheck RA, Clarkin JF, Sirey JA, Salahi J, Struening EL, et al. Stigma as a barrier to recovery: Adverse effects of perceived stigma on social adaptation of persons diagnosed `with bipolar affective disorder. Sychiatr Serv P. 2001;52:162.
31.
go back to reference Boen H, Dalgard OS, Johansen R, Nord E. Socio-demographic, psychosocial and health characteristics of Norwegian senior centre users: A cross-sectional study. Scand J Public Health. 2010;38:508–17. Boen H, Dalgard OS, Johansen R, Nord E. Socio-demographic, psychosocial and health characteristics of Norwegian senior centre users: A cross-sectional study. Scand J Public Health. 2010;38:508–17.
32.
go back to reference Marc A. Kaplan & Sadock's Comprehensive Textbook of Psychiatry. 8th ed. 2005. p. 1169–78. Marc A. Kaplan & Sadock's Comprehensive Textbook of Psychiatry. 8th ed. 2005. p. 1169–78.
33.
go back to reference Arnstein M. European Psychiatry, Smoking in relation to anxiety and depression: Evidence from a large population survey. HUNT Stud. 2008;23:77–8. Arnstein M. European Psychiatry, Smoking in relation to anxiety and depression: Evidence from a large population survey. HUNT Stud. 2008;23:77–8.
Metadata
Title
Prevalence and correlates of depression and anxiety among patients with tuberculosis at WolaitaSodo University Hospital and Sodo Health Center, WolaitaSodo, South Ethiopia, Cross sectional study
Authors
Bereket Duko
Abebaw Gebeyehu
Getnet Ayano
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2015
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-015-0598-3

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