Skip to main content
Top
Published in: BMC Psychiatry 1/2014

Open Access 01-12-2014 | Research article

Ten-year audit of clients presenting to a specialised service for young people experiencing or at increased risk for psychosis

Authors: Agatha M Conrad, Terry J Lewin, Ketrina A Sly, Ulrich Schall, Sean A Halpin, Mick Hunter, Vaughan J Carr

Published in: BMC Psychiatry | Issue 1/2014

Login to get access

Abstract

Background

Despite strong research interest in psychosis risk identification and the potential for early intervention, few papers have sought to document the implementation and evaluation of specialised psychosis related services. Assessment of Ultra High Risk (UHR) has been given priority, but it is equally as important to identify appropriate comparison groups and other baseline differences. This largely descriptive service evaluation paper focuses on the `baseline characteristics’ of referred clients (i.e., previously assessed characteristics or those identified within the first two months following service presentation).

Methods

Data are reported from a 10-year layered service audit of all presentations to a `Psychological Assistance Service’ for young people (PAS, Newcastle, Australia). Baseline socio-demographic and clinical characteristics (N =1,997) are described (including clients’ psychosis and UHR status, previous service contacts, hospitalisation rates, and diagnostic and comorbidity profiles). Key groups are identified and comparisons made between clients who received ongoing treatment and those who were primarily assessed and referred elsewhere.

Results

Clients averaged 19.2 (SD =4.5) years of age and 59% were male. One-tenth of clients (9.6%) were categorised as UHR, among whom there were relatively high rates of attenuated psychotic symptoms (69.1%), comorbid depression (62.3%), anxiety (42.9%), and attentional and related problems (67.5%). Overall, one-fifth (19.8%) experienced a recent psychotic episode, while a further 14.5% were categorised as having an existing psychosis (46.7% with a schizophrenia diagnosis), amongst whom there were relatively high rates of comorbid substance misuse (52.9%), psychosocial (70.2%) and physical health (37.7%) problems. The largest group presenting to PAS were those with non-psychotic disorders (43.7%), who provide a valuable comparison group against which to contrast the health trajectories of those with UHR and recent psychosis. Ongoing treatment by PAS was preferentially given to those experiencing or at risk for psychosis and those reporting greater current distress or dysfunction.

Conclusions

Whether or not UHR clients transition to psychosis, they displayed high rates of comorbid depression and anxiety at service presentation, with half receiving ongoing treatment from PAS. Although international comparisons with similar services are difficult, the socio-demographic and comorbidity patterns observed here were viewed as largely consistent with those reported elsewhere.
Appendix
Available only for authorised users
Literature
1.
go back to reference Yung AR, McGorry PD: The initial prodrome in psychosis: descriptive and qualitative qspects. Aust N Z J Psychiatry. 1996, 30: 587-599. 10.3109/00048679609062654.CrossRefPubMed Yung AR, McGorry PD: The initial prodrome in psychosis: descriptive and qualitative qspects. Aust N Z J Psychiatry. 1996, 30: 587-599. 10.3109/00048679609062654.CrossRefPubMed
2.
go back to reference Yung AR, Phillips LJ, Yuen HP, Francey SM, McFarlane CA, Hallgren M, McGorry PD: Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group. Schizophr Res. 2003, 60: 21-32. 10.1016/S0920-9964(02)00167-6.CrossRefPubMed Yung AR, Phillips LJ, Yuen HP, Francey SM, McFarlane CA, Hallgren M, McGorry PD: Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group. Schizophr Res. 2003, 60: 21-32. 10.1016/S0920-9964(02)00167-6.CrossRefPubMed
3.
go back to reference Yung AR, Nelson B, Stanford C, Simmons MB, Cosgrave EM, Killackey E, Phillips LJ, Bechdolf A, Buckby J, McGorry PD: Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up. Schizophr Res. 2008, 105: 10-17. 10.1016/j.schres.2008.07.012.CrossRefPubMed Yung AR, Nelson B, Stanford C, Simmons MB, Cosgrave EM, Killackey E, Phillips LJ, Bechdolf A, Buckby J, McGorry PD: Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up. Schizophr Res. 2008, 105: 10-17. 10.1016/j.schres.2008.07.012.CrossRefPubMed
4.
go back to reference Yung AR, Nelson B, Thompson A, Wood SJ: The psychosis threshold in Ultra High Risk (prodromal) research: is it valid?. Schizophr Res. 2010, 120: 1-6. 10.1016/j.schres.2010.03.014.CrossRefPubMed Yung AR, Nelson B, Thompson A, Wood SJ: The psychosis threshold in Ultra High Risk (prodromal) research: is it valid?. Schizophr Res. 2010, 120: 1-6. 10.1016/j.schres.2010.03.014.CrossRefPubMed
5.
go back to reference Yung AR: Risk, disorder and diagnosis. Aust N Z J Psychiatry. 2011, 45: 915-919. 10.3109/00048674.2011.614926.CrossRefPubMed Yung AR: Risk, disorder and diagnosis. Aust N Z J Psychiatry. 2011, 45: 915-919. 10.3109/00048674.2011.614926.CrossRefPubMed
6.
go back to reference Fusar-Poli P, Borgwardt S, Bechdolf A, Addington J, Riecher-Rossler A, Schultze-Lutter F, Keshavan M, Wood S, Ruhrmann S, Seidman LJ, Valmaggia L, Cannon T, Velthorst E, De Haan L, Cornblatt B, Bonoldi I, Birchwood M, McGlashan T, Carpenter W, McGorry P, Klosterkotter J, McGuire P, Yung A: The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry. 2013, 70: 107-120. 10.1001/jamapsychiatry.2013.269.CrossRefPubMedPubMedCentral Fusar-Poli P, Borgwardt S, Bechdolf A, Addington J, Riecher-Rossler A, Schultze-Lutter F, Keshavan M, Wood S, Ruhrmann S, Seidman LJ, Valmaggia L, Cannon T, Velthorst E, De Haan L, Cornblatt B, Bonoldi I, Birchwood M, McGlashan T, Carpenter W, McGorry P, Klosterkotter J, McGuire P, Yung A: The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry. 2013, 70: 107-120. 10.1001/jamapsychiatry.2013.269.CrossRefPubMedPubMedCentral
7.
go back to reference Yung AR, Yuen HP, Berger G, Francey S, Hung T-C, Nelson B, Phillips LJ, McGorry PD: Declining transition rate in ultra high risk (prodromal) services: dilution or reduction of risk?. Schizophr Bull. 2007, 33: 673-681. 10.1093/schbul/sbm015.CrossRefPubMedPubMedCentral Yung AR, Yuen HP, Berger G, Francey S, Hung T-C, Nelson B, Phillips LJ, McGorry PD: Declining transition rate in ultra high risk (prodromal) services: dilution or reduction of risk?. Schizophr Bull. 2007, 33: 673-681. 10.1093/schbul/sbm015.CrossRefPubMedPubMedCentral
8.
go back to reference Correll CU, Hauser M, Auther AM, Cornblatt BA: Research in people with psychosis risk syndrome: a review of the current evidence and future directions. J Child Psychol Psychiatry. 2010, 51: 390-431. 10.1111/j.1469-7610.2010.02235.x.CrossRefPubMedPubMedCentral Correll CU, Hauser M, Auther AM, Cornblatt BA: Research in people with psychosis risk syndrome: a review of the current evidence and future directions. J Child Psychol Psychiatry. 2010, 51: 390-431. 10.1111/j.1469-7610.2010.02235.x.CrossRefPubMedPubMedCentral
9.
go back to reference Simon AE, Velthorst E, Nieman DH, Linszen D, Umbricht D, de Haan L: Ultra high-risk state for psychosis and non-transition: A systematic review. Schizophr Res. 2011, 132: 8-17. 10.1016/j.schres.2011.07.002.CrossRefPubMed Simon AE, Velthorst E, Nieman DH, Linszen D, Umbricht D, de Haan L: Ultra high-risk state for psychosis and non-transition: A systematic review. Schizophr Res. 2011, 132: 8-17. 10.1016/j.schres.2011.07.002.CrossRefPubMed
10.
go back to reference McGorry PD: Pre-emptive intervention in psychosis: Agnostic rather than diagnostic. Aust N Z J Psychiatry. 2011, 45: 515-519. 10.3109/00048674.2011.581648.CrossRefPubMed McGorry PD: Pre-emptive intervention in psychosis: Agnostic rather than diagnostic. Aust N Z J Psychiatry. 2011, 45: 515-519. 10.3109/00048674.2011.581648.CrossRefPubMed
11.
go back to reference Jorm AF: `Prodromal diagnosis’ of psychosis: An impartial commentary. Aust N Z J Psychiatry. 2011, 45: 520-523. 10.3109/00048674.2011.585132.CrossRefPubMed Jorm AF: `Prodromal diagnosis’ of psychosis: An impartial commentary. Aust N Z J Psychiatry. 2011, 45: 520-523. 10.3109/00048674.2011.585132.CrossRefPubMed
12.
go back to reference Yung AR: Early intervention in psychosis: evidence, evidence gaps, criticism, and confusion. Aust N Z J Psychiatry. 2012, 46: 7-9. 10.1177/0004867411432205.CrossRefPubMed Yung AR: Early intervention in psychosis: evidence, evidence gaps, criticism, and confusion. Aust N Z J Psychiatry. 2012, 46: 7-9. 10.1177/0004867411432205.CrossRefPubMed
13.
go back to reference Castle D: The truth, and nothing but the truth, about early intervention in psychosis. Aust N Z J Psychiatry. 2012, 46: 10-13. 10.1177/0004867411432553.CrossRefPubMed Castle D: The truth, and nothing but the truth, about early intervention in psychosis. Aust N Z J Psychiatry. 2012, 46: 10-13. 10.1177/0004867411432553.CrossRefPubMed
14.
go back to reference McGorry PD: Truth and reality in early intervention. Aust N Z J Psychiatry. 2012, 46: 313-316. 10.1177/0004867412442172.CrossRefPubMed McGorry PD: Truth and reality in early intervention. Aust N Z J Psychiatry. 2012, 46: 313-316. 10.1177/0004867412442172.CrossRefPubMed
15.
go back to reference Carr VJ: Time to move on? Commentary on the early intervention in psychosis debate. Aust N Z J Psychiatry. 2012, 46: 384-385. 10.1177/0004867412440147.CrossRefPubMed Carr VJ: Time to move on? Commentary on the early intervention in psychosis debate. Aust N Z J Psychiatry. 2012, 46: 384-385. 10.1177/0004867412440147.CrossRefPubMed
16.
go back to reference McGrath JJ: The early intervention debate provides a distraction from another `unspeakable truth’. Aust N Z J Psychiatry. 2012, 46: 681-682. 10.1177/0004867412442023.CrossRefPubMed McGrath JJ: The early intervention debate provides a distraction from another `unspeakable truth’. Aust N Z J Psychiatry. 2012, 46: 681-682. 10.1177/0004867412442023.CrossRefPubMed
17.
go back to reference Castle D: What, after all, is the truth: Response to McGorry. Aust N Z J Psychiatry. 2012, 46: 685-687. 10.1177/0004867412449297.CrossRefPubMed Castle D: What, after all, is the truth: Response to McGorry. Aust N Z J Psychiatry. 2012, 46: 685-687. 10.1177/0004867412449297.CrossRefPubMed
18.
go back to reference Jorm AF: Treatment to reduce risk of psychosis: The need to consider the potential harms as well as the benefits. Aust N Z J Psychiatry. 2013, 47: 881-10.1177/0004867413493526.CrossRefPubMed Jorm AF: Treatment to reduce risk of psychosis: The need to consider the potential harms as well as the benefits. Aust N Z J Psychiatry. 2013, 47: 881-10.1177/0004867413493526.CrossRefPubMed
19.
go back to reference Ehlkes T, Michie PT, Schall U: Brain imaging correlates of emerging schizophrenia. Neuropsychiatry. 2012, 2: 147-154. 10.2217/npy.12.13.CrossRef Ehlkes T, Michie PT, Schall U: Brain imaging correlates of emerging schizophrenia. Neuropsychiatry. 2012, 2: 147-154. 10.2217/npy.12.13.CrossRef
20.
go back to reference Tanskanen S, Morant N, Hinton M, Lloyd-Evans B, Crosby M, Killaspy H, Raine R, Pilling S, Johnson S: Service user and carer experiences of seeking help for a first episode of psychosis: a UK qualitative study. BMC Psychiatry. 2011, 11: 157-10.1186/1471-244X-11-157.CrossRefPubMedPubMedCentral Tanskanen S, Morant N, Hinton M, Lloyd-Evans B, Crosby M, Killaspy H, Raine R, Pilling S, Johnson S: Service user and carer experiences of seeking help for a first episode of psychosis: a UK qualitative study. BMC Psychiatry. 2011, 11: 157-10.1186/1471-244X-11-157.CrossRefPubMedPubMedCentral
21.
go back to reference Preti A, Cella M: Randomized-controlled trials in people at ultra high risk of psychosis: a review of treatment effectiveness. Schizophr Res. 2010, 123: 30-36. 10.1016/j.schres.2010.07.026.CrossRefPubMed Preti A, Cella M: Randomized-controlled trials in people at ultra high risk of psychosis: a review of treatment effectiveness. Schizophr Res. 2010, 123: 30-36. 10.1016/j.schres.2010.07.026.CrossRefPubMed
22.
go back to reference Robinson J, Cotton S, Conus P, Schimmelmann BG, McGorry P, Lambert M: Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis. Aust N Z J Psychiatry. 2009, 43: 149-157. 10.1080/00048670802607162.CrossRefPubMed Robinson J, Cotton S, Conus P, Schimmelmann BG, McGorry P, Lambert M: Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis. Aust N Z J Psychiatry. 2009, 43: 149-157. 10.1080/00048670802607162.CrossRefPubMed
23.
go back to reference Lui S: Risk factors for deliberate self-harm and completed suicide in young Chinese people with schizophrenia. Aust N Z J Psychiatry. 2009, 43: 252-259. 10.1080/00048670802653265.CrossRefPubMed Lui S: Risk factors for deliberate self-harm and completed suicide in young Chinese people with schizophrenia. Aust N Z J Psychiatry. 2009, 43: 252-259. 10.1080/00048670802653265.CrossRefPubMed
24.
go back to reference Larsen T, Melle I, Auestad B, Haahr U, Joa I, Johannessen J, Opjordsmoen S, Rund B, Rossberg J, Simonsen E, Vaglum P, Friis S, McGlashan T: Early detection of psychosis: positive effects on 5-year outcome. Psychol Med. 2011, 41: 1461-1469. 10.1017/S0033291710002023.CrossRefPubMed Larsen T, Melle I, Auestad B, Haahr U, Joa I, Johannessen J, Opjordsmoen S, Rund B, Rossberg J, Simonsen E, Vaglum P, Friis S, McGlashan T: Early detection of psychosis: positive effects on 5-year outcome. Psychol Med. 2011, 41: 1461-1469. 10.1017/S0033291710002023.CrossRefPubMed
25.
go back to reference Connor C, Birchwood M, Palmer C, Channa S, Freemantle N, Lester H, Patterson P, Singh S: Don't turn your back on the symptoms of psychosis: a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK. BMC Psychiatry. 2013, 13: 67-10.1186/1471-244X-13-67.CrossRefPubMedPubMedCentral Connor C, Birchwood M, Palmer C, Channa S, Freemantle N, Lester H, Patterson P, Singh S: Don't turn your back on the symptoms of psychosis: a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK. BMC Psychiatry. 2013, 13: 67-10.1186/1471-244X-13-67.CrossRefPubMedPubMedCentral
26.
go back to reference Marshall M, Lewis S, Lockwood A, Drake R, Jones P, Croudace T: Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. Arch Gen Psychiatry. 2005, 62: 975-983. 10.1001/archpsyc.62.9.975.CrossRefPubMed Marshall M, Lewis S, Lockwood A, Drake R, Jones P, Croudace T: Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. Arch Gen Psychiatry. 2005, 62: 975-983. 10.1001/archpsyc.62.9.975.CrossRefPubMed
27.
go back to reference Malla A, Norman R, Scholten D, Machanda R, Mclean T: A community intervention for the early identification of first episode psychosis impact on duration of untreated psychosis (DUP) and patient characteristics. Soc Psychiatry Psychiatr Epidemiol. 2005, 40: 337-344. 10.1007/s00127-005-0901-6.CrossRefPubMed Malla A, Norman R, Scholten D, Machanda R, Mclean T: A community intervention for the early identification of first episode psychosis impact on duration of untreated psychosis (DUP) and patient characteristics. Soc Psychiatry Psychiatr Epidemiol. 2005, 40: 337-344. 10.1007/s00127-005-0901-6.CrossRefPubMed
28.
go back to reference Blanchard JJ, Brown SA, Horan WP, Sherwood AR: Substance use disorders in schizophrenia: Review, integration, and a proposed model. Clin Psychol Rev. 2000, 20: 207-234. 10.1016/S0272-7358(99)00033-1.CrossRefPubMed Blanchard JJ, Brown SA, Horan WP, Sherwood AR: Substance use disorders in schizophrenia: Review, integration, and a proposed model. Clin Psychol Rev. 2000, 20: 207-234. 10.1016/S0272-7358(99)00033-1.CrossRefPubMed
29.
go back to reference Kavanagh DJ, Waghorn G, Jenner L, Chant DC, Carr V, Evans M, Herrman H, Jablensky A, McGrath JJ: Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample. Schizophr Res. 2004, 66: 115-124. 10.1016/S0920-9964(03)00130-0.CrossRefPubMed Kavanagh DJ, Waghorn G, Jenner L, Chant DC, Carr V, Evans M, Herrman H, Jablensky A, McGrath JJ: Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample. Schizophr Res. 2004, 66: 115-124. 10.1016/S0920-9964(03)00130-0.CrossRefPubMed
30.
go back to reference Moore E, Mancuso SG, Slade T, Galletly C, Castle DJ: The impact of alcohol and illicit drugs on people with psychosis: The second Australian national survey of psychosis. Aust N Z J Psychiatry. 2012, 46: 864-878. 10.1177/0004867412443900.CrossRefPubMed Moore E, Mancuso SG, Slade T, Galletly C, Castle DJ: The impact of alcohol and illicit drugs on people with psychosis: The second Australian national survey of psychosis. Aust N Z J Psychiatry. 2012, 46: 864-878. 10.1177/0004867412443900.CrossRefPubMed
31.
go back to reference Romm KL, Rossberg JI, Berg AO, Hansen CF, Andreassen OA, Melle I: Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure. Eur Psychiatry. 2011, 26: 115-121. 10.1016/j.eurpsy.2010.08.014.CrossRefPubMed Romm KL, Rossberg JI, Berg AO, Hansen CF, Andreassen OA, Melle I: Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure. Eur Psychiatry. 2011, 26: 115-121. 10.1016/j.eurpsy.2010.08.014.CrossRefPubMed
32.
go back to reference Yung AR, Phillips LJ, Yuen HP, McGorry PD: Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr Res. 2004, 67: 131-142. 10.1016/S0920-9964(03)00192-0.CrossRefPubMed Yung AR, Phillips LJ, Yuen HP, McGorry PD: Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr Res. 2004, 67: 131-142. 10.1016/S0920-9964(03)00192-0.CrossRefPubMed
33.
go back to reference Velthorst E, Nieman DH, Becker HE, van de Fliert R, Dingemans PM, Klaassen R, de Haan L, van Amelsvoort T, Linszen DH: Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis. Schizophr Res. 2009, 109: 60-65. 10.1016/j.schres.2009.02.002.CrossRefPubMed Velthorst E, Nieman DH, Becker HE, van de Fliert R, Dingemans PM, Klaassen R, de Haan L, van Amelsvoort T, Linszen DH: Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis. Schizophr Res. 2009, 109: 60-65. 10.1016/j.schres.2009.02.002.CrossRefPubMed
34.
go back to reference Addington J, Cornblatt B, Cadenhead K, Cannon T, McGlashan T, Perkins D, Seidman L, Tsuang M, Walker E, Woods S, Heinssen R: At clinical high risk for psychosis: Outcome for nonconverters. Am J Psychiatry. 2011, 168: 800-805. 10.1176/appi.ajp.2011.10081191.CrossRefPubMedPubMedCentral Addington J, Cornblatt B, Cadenhead K, Cannon T, McGlashan T, Perkins D, Seidman L, Tsuang M, Walker E, Woods S, Heinssen R: At clinical high risk for psychosis: Outcome for nonconverters. Am J Psychiatry. 2011, 168: 800-805. 10.1176/appi.ajp.2011.10081191.CrossRefPubMedPubMedCentral
35.
go back to reference Varghese D, Scott J, Welham J, Bor W, Najman J, O'Callaghan M, Williams G, McGrath J: Psychotic-like experiences in major depression and anxiety disorders: A population-based survey in young adults. Schizophr Bull. 2011, 37: 389-393. 10.1093/schbul/sbp083.CrossRefPubMed Varghese D, Scott J, Welham J, Bor W, Najman J, O'Callaghan M, Williams G, McGrath J: Psychotic-like experiences in major depression and anxiety disorders: A population-based survey in young adults. Schizophr Bull. 2011, 37: 389-393. 10.1093/schbul/sbp083.CrossRefPubMed
36.
go back to reference Häfner H, Maurer K, Trendler G, An der Heiden W, Schmidt M: The early course of schizophrenia and depression. Eur Arch Psychiatry Clin Nuerosci. 2005, 255: 167-173. 10.1007/s00406-005-0584-8.CrossRef Häfner H, Maurer K, Trendler G, An der Heiden W, Schmidt M: The early course of schizophrenia and depression. Eur Arch Psychiatry Clin Nuerosci. 2005, 255: 167-173. 10.1007/s00406-005-0584-8.CrossRef
37.
go back to reference Weiser M, van Os J, Davidson M: Time for a shift in focus in schizophrenia: from narrow phenotypes to broad endophenotypes. Br J Psychiatry. 2005, 187: 203-205. 10.1192/bjp.187.3.203.CrossRefPubMed Weiser M, van Os J, Davidson M: Time for a shift in focus in schizophrenia: from narrow phenotypes to broad endophenotypes. Br J Psychiatry. 2005, 187: 203-205. 10.1192/bjp.187.3.203.CrossRefPubMed
38.
go back to reference Kotov R, Chang S-W, Fochtmann LJ, Mojtabai R, Carlson GA, Sedler MJ, Bromet EJ: Schizophrenia in the internalizing-externalizing framework: A third dimension?. Schizophr Bull. 2011, 37: 1168-1178. 10.1093/schbul/sbq024.CrossRefPubMed Kotov R, Chang S-W, Fochtmann LJ, Mojtabai R, Carlson GA, Sedler MJ, Bromet EJ: Schizophrenia in the internalizing-externalizing framework: A third dimension?. Schizophr Bull. 2011, 37: 1168-1178. 10.1093/schbul/sbq024.CrossRefPubMed
39.
go back to reference van Nierop M, van Os J, Gunther N, Myin-Germeys I, de Graaf R, ten Have M, van Dorsselaer S, Bak M, van Winkel R: Phenotypically continuous with clinical psychosis, discontinuous in need for care: evidence for an extended psychosis phenotype. Schizophr Bull. 2012, 38: 231-238. 10.1093/schbul/sbr129.CrossRefPubMed van Nierop M, van Os J, Gunther N, Myin-Germeys I, de Graaf R, ten Have M, van Dorsselaer S, Bak M, van Winkel R: Phenotypically continuous with clinical psychosis, discontinuous in need for care: evidence for an extended psychosis phenotype. Schizophr Bull. 2012, 38: 231-238. 10.1093/schbul/sbr129.CrossRefPubMed
40.
go back to reference Wigman JTW, van Nierop M, Vollebergh WAM, Lieb R, Beesdo-Baum K, Wittchen H-U, van Os J: Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity - implications for diagnosis and ultra–high risk research. Schizophr Bull. 2012, 38: 247-257. 10.1093/schbul/sbr196.CrossRefPubMedPubMedCentral Wigman JTW, van Nierop M, Vollebergh WAM, Lieb R, Beesdo-Baum K, Wittchen H-U, van Os J: Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity - implications for diagnosis and ultra–high risk research. Schizophr Bull. 2012, 38: 247-257. 10.1093/schbul/sbr196.CrossRefPubMedPubMedCentral
41.
go back to reference Carr V, Halpin S, Lau N, O'Brien S, Beckmann J, Lewin T: A risk factor screening and assessment protocol for schizophrenia and related psychosis. Aust N Z J Psychiatry. 2000, 34: S170-S180. 10.1046/j.1440-1614.2000.00792.x.CrossRefPubMed Carr V, Halpin S, Lau N, O'Brien S, Beckmann J, Lewin T: A risk factor screening and assessment protocol for schizophrenia and related psychosis. Aust N Z J Psychiatry. 2000, 34: S170-S180. 10.1046/j.1440-1614.2000.00792.x.CrossRefPubMed
42.
go back to reference Phillips LJ, Yung AR, McGorry PD: Identification of young people at risk of psychosis: validation of Personal Assessment and Crisis Evaluation Clinic intake criteria. Aust N Z J Psychiatry. 2000, 34 (Suppl): S164-169. 10.1046/j.1440-1614.2000.00798.x.CrossRefPubMed Phillips LJ, Yung AR, McGorry PD: Identification of young people at risk of psychosis: validation of Personal Assessment and Crisis Evaluation Clinic intake criteria. Aust N Z J Psychiatry. 2000, 34 (Suppl): S164-169. 10.1046/j.1440-1614.2000.00798.x.CrossRefPubMed
43.
go back to reference Power P, McGuire P, Iacoponi E, Garety P, Morris E, Valmaggia L, Grafton D, Craig T: Lambeth Early Onset (LEO) and Outreach & Support in South London (OASIS) service. Early Interv Psychiatry. 2007, 1: 97-103. 10.1111/j.1751-7893.2007.00010.x.CrossRefPubMed Power P, McGuire P, Iacoponi E, Garety P, Morris E, Valmaggia L, Grafton D, Craig T: Lambeth Early Onset (LEO) and Outreach & Support in South London (OASIS) service. Early Interv Psychiatry. 2007, 1: 97-103. 10.1111/j.1751-7893.2007.00010.x.CrossRefPubMed
44.
go back to reference Yung AR, McGorry PD, Francey SM, Nelson B, Baker K, Phillips LJ, Berger G, Amminger GP: PACE: a specialised service for young people at risk of psychotic disorders. Med J Aust. 2007, 187: S43-46.PubMed Yung AR, McGorry PD, Francey SM, Nelson B, Baker K, Phillips LJ, Berger G, Amminger GP: PACE: a specialised service for young people at risk of psychotic disorders. Med J Aust. 2007, 187: S43-46.PubMed
45.
go back to reference Schultze-Lutter F, Ruhrmann S, Klosterkotter J: Early detection of psychosis - establishing a service for persons at risk. Eur Psychiatry. 2009, 24: 1-10. 10.1016/j.eurpsy.2008.08.004.CrossRefPubMed Schultze-Lutter F, Ruhrmann S, Klosterkotter J: Early detection of psychosis - establishing a service for persons at risk. Eur Psychiatry. 2009, 24: 1-10. 10.1016/j.eurpsy.2008.08.004.CrossRefPubMed
46.
go back to reference Meneghelli A, Cocchi A, Preti A: 'Programma2000': a multi-modal pilot programme on early intervention in psychosis underway in Italy since 1999. Early Interv Psychiatry. 2010, 4: 97-103. 10.1111/j.1751-7893.2009.00158.x.CrossRefPubMed Meneghelli A, Cocchi A, Preti A: 'Programma2000': a multi-modal pilot programme on early intervention in psychosis underway in Italy since 1999. Early Interv Psychiatry. 2010, 4: 97-103. 10.1111/j.1751-7893.2009.00158.x.CrossRefPubMed
47.
go back to reference Uzenoff SR, Penn DL, Graham KA, Saade S, Smith BB, Perkins DO: Evaluation of a multi-element treatment center for early psychosis in the United States. Soc Psychiatry Psychiatr Epidemiol. 2012, 47: 1607-1615. 10.1007/s00127-011-0467-4.CrossRefPubMed Uzenoff SR, Penn DL, Graham KA, Saade S, Smith BB, Perkins DO: Evaluation of a multi-element treatment center for early psychosis in the United States. Soc Psychiatry Psychiatr Epidemiol. 2012, 47: 1607-1615. 10.1007/s00127-011-0467-4.CrossRefPubMed
48.
go back to reference Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton MJ, Valmaggia L, Barale F, Caverzasi E, McGuire P: Predicting psychosis: Meta-analysis of transition outcomes in individuals at high clinical risk. Arch Gen Psychiatry. 2012, 69: 220-229. 10.1001/archgenpsychiatry.2011.1472.CrossRefPubMed Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton MJ, Valmaggia L, Barale F, Caverzasi E, McGuire P: Predicting psychosis: Meta-analysis of transition outcomes in individuals at high clinical risk. Arch Gen Psychiatry. 2012, 69: 220-229. 10.1001/archgenpsychiatry.2011.1472.CrossRefPubMed
49.
go back to reference Phillips LJ, Velakoulis D, Pantelis C, Wood S, Yuen HP, Yung AR, Desmond P, Brewer W, McGorry PD: Non-reduction in hippocampal volume is associated with higher risk of psychosis. Schizophr Res. 2002, 58: 145-158. 10.1016/S0920-9964(01)00392-9.CrossRefPubMed Phillips LJ, Velakoulis D, Pantelis C, Wood S, Yuen HP, Yung AR, Desmond P, Brewer W, McGorry PD: Non-reduction in hippocampal volume is associated with higher risk of psychosis. Schizophr Res. 2002, 58: 145-158. 10.1016/S0920-9964(01)00392-9.CrossRefPubMed
50.
go back to reference Cocchi A, Meneghelli A, Erlicher A, Pisano A, Cascio M, Preti A: Patterns of referral in first-episode schizophrenia and ultra high-risk individuals: results from an early intervention program in Italy. Soc Psychiatry Psychiatr Epidemiol. 2013, 48: 1905-1916. 10.1007/s00127-013-0736-5.CrossRefPubMed Cocchi A, Meneghelli A, Erlicher A, Pisano A, Cascio M, Preti A: Patterns of referral in first-episode schizophrenia and ultra high-risk individuals: results from an early intervention program in Italy. Soc Psychiatry Psychiatr Epidemiol. 2013, 48: 1905-1916. 10.1007/s00127-013-0736-5.CrossRefPubMed
51.
go back to reference Yung AR, Pan Yuen H, Mcgorry PD, Phillips LJ, Kelly D, Dell'olio M, Francey SM, Cosgrave EM, Killackey E, Stanford C, Godfrey K, Buckby J: Mapping the onset of psychosis: the Comprehensive Assessment of at-Risk Mental States. Aust N Z J Psychiatry. 2005, 39: 964-971. 10.1080/j.1440-1614.2005.01714.x.CrossRefPubMed Yung AR, Pan Yuen H, Mcgorry PD, Phillips LJ, Kelly D, Dell'olio M, Francey SM, Cosgrave EM, Killackey E, Stanford C, Godfrey K, Buckby J: Mapping the onset of psychosis: the Comprehensive Assessment of at-Risk Mental States. Aust N Z J Psychiatry. 2005, 39: 964-971. 10.1080/j.1440-1614.2005.01714.x.CrossRefPubMed
52.
go back to reference A Contributing Life: The 2013 National Report Card on Mental Health and Suicide Prevention. 2013, NMHC, Sydney A Contributing Life: The 2013 National Report Card on Mental Health and Suicide Prevention. 2013, NMHC, Sydney
53.
go back to reference Yung AR, Stanford C, Cosgrave E, Killackey E, Phillips LJ, Nelson B, McGorry PD: Testing the Ultra High Risk (prodromal) criteria for the prediction of psychosis in a clinical sample of young people. Schizophr Res. 2006, 84: 57-66. 10.1016/j.schres.2006.03.014.CrossRefPubMed Yung AR, Stanford C, Cosgrave E, Killackey E, Phillips LJ, Nelson B, McGorry PD: Testing the Ultra High Risk (prodromal) criteria for the prediction of psychosis in a clinical sample of young people. Schizophr Res. 2006, 84: 57-66. 10.1016/j.schres.2006.03.014.CrossRefPubMed
54.
go back to reference Rickwood DJ, Telford NR, Parker AG, Tanti CJ, McGorry PD: Headspace - Australia's innovation in youth mental health: who are the clients and why are they presenting?. Med J Aust. 2014, 200: 108-111. 10.5694/mja13.11235.CrossRefPubMed Rickwood DJ, Telford NR, Parker AG, Tanti CJ, McGorry PD: Headspace - Australia's innovation in youth mental health: who are the clients and why are they presenting?. Med J Aust. 2014, 200: 108-111. 10.5694/mja13.11235.CrossRefPubMed
Metadata
Title
Ten-year audit of clients presenting to a specialised service for young people experiencing or at increased risk for psychosis
Authors
Agatha M Conrad
Terry J Lewin
Ketrina A Sly
Ulrich Schall
Sean A Halpin
Mick Hunter
Vaughan J Carr
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2014
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-014-0318-4

Other articles of this Issue 1/2014

BMC Psychiatry 1/2014 Go to the issue