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Open Access 01-12-2019 | Child Maltreatment | Research article

Association of cleft lip and palate on mother-to-infant bonding: a cross-sectional study in the Japan Environment and Children’s Study (JECS)

Authors: Shinobu Tsuchiya, Masahiro Tsuchiya, Haruki Momma, Takeyoshi Koseki, Kaoru Igarashi, Ryoichi Nagatomi, Takahiro Arima, Nobuo Yaegashi, Japan Environment & Children’s Study Group

Published in: BMC Pediatrics | Issue 1/2019

Abstract

Background

Cleft lip and/or palate is among the most prevalent congenital birth defects, and negatively affects maternal psychological status and may consequently result in higher prevalence of child maltreatment. However, the association of childbirths of infants with cleft lip and/or palate with maternal emotional involvement still remains unclear. We examined the association between childbirths of infants with cleft lip and/or palate and mother-to-infant bonding, using data from the Japan Environment and Children’s Study, a nationwide birth cohort study.

Methods

A cross-sectional study using the jecs-an-20,180,131 dataset was performed. A total 104,065 fetuses in 15 regional centres in Japan were enrolled after obtaining informed written consent. The Mother-to-Infant Bonding Scale, a self-report scale consisting of 10 items, was used to evaluate maternal bonding at one year after childbirth. Finally, the participants consisted of 79,140 mother-infant pairs, of which 211 mothers of infants with cleft lip and/or palate were included in our analyses. Multivariable logistic regression analysis using multiple imputation for missing data was performed to calculate the odds ratio and 95% confidence interval in the estimation of the association between bonding disorders and childbirths with cleft lip and/or palate.

Results

No increased risk of bonding disorders was observed among all the mothers of infants with cleft lip and/or palate (odds ratio [95% confidence interval]; 0.97 [0.63–1.48], p = 0.880), however, advanced maternal age or multiple parity may adversely affect the associations between bonding disorders and cleft lip and/or palate, respectively. After stratification with a combination of maternal age and parity, a significant association of cleft lip and/or palate with bonding disorders was found only among advanced-age multiparae (odds ratio [95% confidence interval] = 2.51 [1.17–5.37], p = 0.018), but it was weakened after additional adjustment for maternal depression.

Conclusions

Childbirths of infants with cleft lip and/or palate may increase the risk of bonding disorders among advanced-age multiparae, possibly through maternal depression. This finding provides valuable information for the provision of multidisciplinary cleft care.

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The Centre of the International Clearinghouse for Birth Defects Surveillance and Research. Annual Report 2014. In. Roma, Italy: The Centre of the International Clearinghouse for Birth Defects Surveillance and Research; 2014.

Natsume N, Kawai T, Kohama G, Teshima T, Kochi S, Ohashi Y, et al. Incidence of cleft lip or palate in 303738 Japanese babies born between 1994 and 1995. Br J Oral Maxillofac Surg. 2000;38:605–7.PubMedCrossRef

Mezawa H, Tomotaki A, Yamamoto-Hanada K, Ishitsuka K, Ayabe T, Konishi M, et al. Prevalence of congenital anomalies in the Japan environment and Children's study. J Epidemiol. 2018.

Bekisz JM, Fryml E, Flores RL. A review of randomized controlled trials in cleft and craniofacial surgery. J Craniofac Surg. 2018;29:293–301.PubMed

Takemura H, Yasumoto K, Toi T, Hosoyamada A. Correlation of cleft type with incidence of perioperative respiratory complications in infants with cleft lip and palate. Paediatr Anaesth. 2002;12:585–8.PubMedCrossRef

Ize-Iyamu IN, Saheeb BD. Feeding intervention in cleft lip and palate babies: a practical approach to feeding efficiency and weight gain. Int J Oral Maxillofac Surg. 2011;40:916–9.PubMedCrossRef

Gottschlich MM, Mayes T, Allgeier C, James L, Khoury J, Pan B, et al. A retrospective study identifying breast Milk feeding disparities in infants with cleft palate. J Acad Nutr Diet. 2018;118:2154–61.PubMedCrossRef

Montirosso R, Fedeli C, Murray L, Morandi F, Brusati R, Perego GG, et al. The role of negative maternal affective states and infant temperament in early interactions between infants with cleft lip and their mothers. J Pediatr Psychol. 2012;37:241–50.PubMedCrossRef

Johns AL, Hershfield JA, Seifu NM, Haynes KA. Postpartum depression in mothers of infants with cleft lip and/or palate. J Craniofac Surg. 2018;29:e354–8.PubMedCrossRef

10.

Van Horne BS, Caughy MO, Canfield M, Case AP, Greeley CS, Morgan R, et al. First-time maltreatment in children ages 2-10 with and without specific birth defects: a population-based study. Child Abuse Negl. 2018;84:53–63.PubMedCrossRef

11.

Van Horne BS, Moffitt KB, Canfield MA, Case AP, Greeley CS, Morgan R, et al. Maltreatment of children under age 2 with specific birth defects: a population-based study. Pediatrics. 2015;136:e1504–12.PubMedCrossRef

12.

Boztepe H, Ay A, Kerimoglu Yildiz G, Cinar S. Does the visibility of a congenital anomaly affect maternal-infant attachment levels? J Spec Pediatr Nurs. 2016;21:200–11.PubMedCrossRef

13.

Borghini A, Despars J, Habersaat S, Turpin H, Monnier M, Ansermet F, et al. Attachment in infants with cleft lip and/or palate: marginal security and its changes over time. Infant Ment Health J. 2018;39:242–53.PubMedCrossRef

14.

Coy K, Speltz ML, Jones K. Facial appearance and attachment in infants with orofacial clefts: a replication. Cleft Palate Craniofac J. 2002;39:66–72.PubMedCrossRef

15.

Despars J, Peter C, Borghini A, Pierrehumbert B, Habersaat S, Muller-Nix C, et al. Impact of a cleft lip and/or palate on maternal stress and attachment representations. Cleft Palate Craniofac J. 2011;48:419–24.PubMedCrossRef

16.

Bowlby J. The nature of the child's tie to his mother. Int J Psychoanal. 1958;39:350–73.PubMed

17.

Kumar RC. "Anybody's child": severe disorders of mother-to-infant bonding. Br J Psychiatry. 1997;171:175–81.PubMedCrossRef

18.

Matsunaga A, Takauma F, Tada K, Kitamura T. Discrete category of mother-to-infant bonding disorder and its identification by the mother-to-infant bonding scale: a study in Japanese mothers of a 1-month-old. Early Hum Dev. 2017;111:1–5.PubMedCrossRef

19.

Brockington IF, Fraser C, Wilson D. The postpartum bonding questionnaire: a validation. Arch Womens Ment Health. 2006;9:233–42.PubMedCrossRef

20.

Brancato A, Cannizzaro C. Mothering under the influence: how perinatal drugs of abuse alter the mother-infant interaction. Rev Neurosci. 2018;29:283–94.PubMedCrossRef

21.

Choi H, Yamashita T, Wada Y, Narumoto J, Nanri H, Fujimori A, et al. Factors associated with postpartum depression and abusive behavior in mothers with infants. Psychiatry Clin Neurosci. 2010;64:120–7.PubMedCrossRef

22.

Yoshida K, Yamashita H, Conroy S, Marks M, Kumar C. A Japanese version of mother-to-infant bonding scale: factor structure, longitudinal changes and links with maternal mood during the early postnatal period in Japanese mothers. Arch Womens Ment Health. 2012;15:343–52.PubMedPubMedCentralCrossRef

23.

Badr LK, Ayvazian N, Lameh S, Charafeddine L. Is the effect of postpartum depression on mother-infant bonding universal? Infant Behav Dev. 2018;51:15–23.PubMedCrossRef

24.

Ohara M, Nakatochi M, Okada T, Aleksic B, Nakamura Y, Shiino T, et al. Impact of perceived rearing and social support on bonding failure and depression among mothers: a longitudinal study of pregnant women. J Psychiatr Res. 2018;105:71–7.PubMedCrossRef

25.

Caldas IFR, Garotti MF, Shiramizu VKM, Pereira A. The socio-communicative development of preterm infants is resistant to the negative effects of parity on maternal responsiveness. Front Psychol. 2018;9:43.PubMedPubMedCentralCrossRef

26.

Mirhosseini H, Moosavipoor SA, Nazari MA, Dehghan A, Mirhosseini S, Bidaki R, et al. Cognitive behavioral development in children following maternal postpartum depression: a review article. Electron Physician. 2015;7:1673–9.PubMedPubMedCentralCrossRef

27.

Kawamoto T, Nitta H, Murata K, Toda E, Tsukamoto N, Hasegawa M, et al. Rationale and study design of the Japan environment and children's study (JECS). BMC Public Health. 2014;14:25.PubMedPubMedCentralCrossRef

28.

Michikawa T, Nitta H, Nakayama SF, Yamazaki S, Isobe T, Tamura K, et al. Baseline profile of participants in the Japan environment and Children's study (JECS). J Epidemiol. 2018;28:99–104.PubMedPubMedCentralCrossRef

29.

Yokoyama Y, Takachi R, Ishihara J, Ishii Y, Sasazuki S, Sawada N, et al. Validity of short and long self-administered food frequency questionnaires in ranking dietary intake in middle-aged and elderly Japanese in the Japan public health center-based prospective study for the Next generation (JPHC-NEXT) protocol area. J Epidemiol. 2016;26:420–32.PubMedCrossRef

30.

Watanabe Z, Iwama N, Nishigori H, Nishigori T, Mizuno S, Sakurai K, et al. Psychological distress during pregnancy in Miyagi after the great East Japan earthquake: the Japan environment and Children's study. J Affect Disord. 2016;190:341–8.PubMedCrossRef

31.

Berg E, Lie RT, Sivertsen A, Haaland OA. Parental age and the risk of isolated cleft lip: a registry-based study. Ann Epidemiol. 2015;25:942–947 e941.PubMedCrossRef

32.

Cummings P. Missing data and multiple imputation. JAMA Pediatr. 2013;167:656–61.PubMedCrossRef

33.

Rubin DB, Schenker N. Multiple imputation in health-care databases: an overview and some applications. Stat Med. 1991;10:585–98.PubMedCrossRef

34.

Rossen L, Hutchinson D, Wilson J, Burns L, Allsop S, Elliott EJ, et al. Maternal bonding through pregnancy and postnatal: findings from an Australian longitudinal study. Am J Perinatol. 2017;34:808–17.PubMedCrossRef

35.

Ustunsoz A, Guvenc G, Akyuz A, Oflaz F. Comparison of maternal-and paternal-fetal attachment in Turkish couples. Midwifery. 2010;26:e1–9.PubMedCrossRef

36.

Condon JT, Esuvaranathan V. The influence of parity on the experience of pregnancy: a comparison of first- and second-time expectant couples. Br J Med Psychol. 1990;63(Pt 4):369–77.PubMedCrossRef

37.

van Bakel HJ, Maas AJ, Vreeswijk CM, Vingerhoets AJ. Pictorial representation of attachment: measuring the parent-fetus relationship in expectant mothers and fathers. BMC Pregnancy Childbirth. 2013;13:138.PubMedPubMedCentralCrossRef

38.

Mori E, Tsuchiya M, Maehara K, Iwata H, Sakajo A, Tamakoshi K. Fatigue, depression, maternal confidence, and maternal satisfaction during the first month postpartum: a comparison of Japanese mothers by age and parity. Int J Nurs Pract. 2017;23.CrossRef

39.

Iwata H, Mori E, Sakajo A, Aoki K, Maehara K, Tamakoshi K. Prevalence of postpartum depressive symptoms during the first 6 months postpartum: association with maternal age and parity. J Affect Disord. 2016;203:227–32.PubMedCrossRef

40.

Tsuchida A, Hamazaki K, Matsumura K, Miura K, Kasamatsu H, Inadera H, et al. Changes in the association between postpartum depression and mother-infant bonding by parity: longitudinal results from the Japan environment and Children's study. J Psychiatr Res. 2019;110:110–6.PubMedCrossRef

41.

Nakano M, Upadhyaya S, Chudal R, Skokauskas N, Luntamo T, Sourander A, et al. Risk factors for impaired maternal bonding when infants are 3 months old: a longitudinal population based study from Japan. BMC Psychiatry. 2019;19:87.PubMedPubMedCentralCrossRef

42.

Grosen D, Chevrier C, Skytthe A, Bille C, Molsted K, Sivertsen A, et al. A cohort study of recurrence patterns among more than 54,000 relatives of oral cleft cases in Denmark: support for the multifactorial threshold model of inheritance. J Med Genet. 2010;47:162–8.PubMedCrossRef

43.

Klotz CM, Wang X, Desensi RS, Grubs RE, Costello BJ, Marazita ML. Revisiting the recurrence risk of nonsyndromic cleft lip with or without cleft palate. Am J Med Genet A. 2010;152A:2697–702.PubMedPubMedCentralCrossRef

44.

Tanimura M, Matsui I, Kobayashi N. Child abuse of one of a pair of twins in Japan. Lancet. 1990;336:1298–9.PubMedCrossRef

45.

Pedersen MS, Wehby GL, Pedersen DA, Christensen K. Long-term effects of oral clefts on health care utilization: a sibling comparison. Eur J Health Econ. 2015;16:603–12.PubMedCrossRef

Title: Association of cleft lip and palate on mother-to-infant bonding: a cross-sectional study in the Japan Environment and Children’s Study (JECS)
Authors: Shinobu Tsuchiya
Masahiro Tsuchiya
Haruki Momma
Takeyoshi Koseki
Kaoru Igarashi
Ryoichi Nagatomi
Takahiro Arima
Nobuo Yaegashi
Japan Environment & Children’s Study Group
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Child Maltreatment
Child Maltreatment
Published in: BMC Pediatrics / Issue 1/2019
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-019-1877-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Association of cleft lip and palate on mother-to-infant bonding: a cross-sectional study in the Japan Environment and Children’s Study (JECS)

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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