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BMC Pediatrics

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Open Access 01-12-2018 | Case report

Group B streptococcus late-onset disease,contaminated breast milk and mothers persistently GBS negative: report of 3cases

Authors: Giangiacomo Nicolini, Martina Borellini, Vitaliana Loizzo, Roberta Creti, Luigi Memo, Alberto Berardi

Published in: BMC Pediatrics | Issue 1/2018

Abstract

Background

Human milk is fundamental for its nutritional properties and to protect newborns, but it is not sterile and can sometime transmit bacteria. Few anecdotal cases suggest that breast milk could be a possible source of group B Streptococcus (GBS) late onset disease, although the pathogenesis is not entirely understood.

Case presentation

We report 3 cases of GBS late onset disease in full-term newborns. Fresh breast milk cultures yielded GBS, but mothers of neonates had no signs of mastitis and remained persistently GBS negative at rectovaginal site.

Conclusions

Breast milk containing group B Streptococcus can be a risk factor for late onset disease. The persistent negative maternal GBS status supports the assumption that newborns, colonised in the throat, could be the initial source of GBS, while the mammary gland could act as a GBS replication site. It is unclear whether a low bacterial load may represent only contamination rather than true milk infection.

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Title: Group B streptococcus late-onset disease,contaminated breast milk and mothers persistently GBS negative: report of 3cases
Authors: Giangiacomo Nicolini
Martina Borellini
Vitaliana Loizzo
Roberta Creti
Luigi Memo
Alberto Berardi
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Pediatrics / Issue 1/2018
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-018-1192-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Group B streptococcus late-onset disease,contaminated breast milk and mothers persistently GBS negative: report of 3cases

Abstract

Background

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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