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BMC Pediatrics

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Open Access 01-12-2014 | Research article

Ambient air pollution and birth defects in Haikou city, Hainan province

Authors: Zhijiang Liang, Li Wu, Lichun Fan, Qingguo Zhao

Published in: BMC Pediatrics | Issue 1/2014

Abstract

Background

Evidence shows exposure to ambient air pollution during pregnancy was associated with an increased risk of adverse birth outcomes, such as preterm birth, low birth weight and intrauterine growth retardation, but the results for birth defects have been inconsistent.

Methods

The data on birth defects was collected from the Birth Defects Monitoring Network of Haikou city. Air pollution data for PM₁₀, SO₂ and NO₂ were obtained from Haikou Environmental Monitoring Center. Logistic regression analysis was used to evaluate these associations.

Results

The risk of birth defects was related to PM₁₀ levels (adjusted OR = 1.039; 95% CI = 1.016-1.063) and SO₂ levels (adjusted OR = 0.843; 95% CI = 0.733-0.969) for the second month of pregnancy. In the third month of pregnancy, the risk of birth defects was also related to PM10 levels (adjusted OR = 1.066; 95% CI = 1.043-1.090) and SO₂ levels (adjusted OR = 0.740; 95% CI = 0.645-0.850).

Conclusion

The study provides evidence that exposure to PM₁₀ and SO₂ during the second and third month of pregnancy may associated with the risk of birth defects.

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Title: Ambient air pollution and birth defects in Haikou city, Hainan province
Authors: Zhijiang Liang
Li Wu
Lichun Fan
Qingguo Zhao
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: BMC Pediatrics / Issue 1/2014
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-014-0283-6

At a glance: The STEP trials

Springer Medicine

Ambient air pollution and birth defects in Haikou city, Hainan province

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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