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BMC Ophthalmology

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01-12-2020 | Refractive Surgery | Research article

A pilot study: lenticule quality of hyperopic small incision lenticule extraction (SMILE) in rabbits

Authors: Yu Zhao, Feng Zhao, Tian Han, Jing Zhao, Xingtao Zhou

Published in: BMC Ophthalmology | Issue 1/2020

Abstract

Background

To evaluate lenticule surface characteristics of small incision lenticule extraction (SMILE) for hyperopia correction in rabbits.

Methods

The left and right eyes of 8 rabbits were divided into two groups. The right eyes were assigned to a myopia group, and the left eyes to a hyperopia group. The rabbits received SMILE procedures with + 3.00 D and − 3.00 D correction for the hyperopia and myopia groups, respectively. Extracted lenticules were examined via scanning electron microscopy. Lenticules from odd-numbered rabbits were accessed with the anterior surface, and lenticules from even-numbered rabbits were observed with the posterior surface. A previously established scoring system was used to evaluate lenticule surface characteristics. Statistical analysis was conducted to compare the scores between the two groups.

Results

All procedures were performed successfully, and the lenticules were extracted smoothly. One myopia lenticule that was facing downward was handled failed in preparation for imaging, thus 15 lenticules were ultimately graded. Twelve lenticules exhibited smooth surfaces, and regularly arranged tissue bridges were observed in almost all regions. Three lenticules exhibited a partially rough surface and irregularities affecting more than 10% of the lenticules (2 in the hyperopia group and 1 in the myopia group). Rough lenticules occurred in twice as many lenticules in the hyperopia group compared to the myopia group.

Conclusions

Scan quality of lenticules after SMILE for hyperopia correction is comparable to that of myopia lenticules. The shape of hyperopic lenticule may increase the difficulty of surgical manipulation and result in surface roughness.

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Title: A pilot study: lenticule quality of hyperopic small incision lenticule extraction (SMILE) in rabbits
Authors: Yu Zhao
Feng Zhao
Tian Han
Jing Zhao
Xingtao Zhou
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Refractive Surgery
Incision
Laser
Published in: BMC Ophthalmology / Issue 1/2020
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-020-01432-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A pilot study: lenticule quality of hyperopic small incision lenticule extraction (SMILE) in rabbits

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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