Skip to main content
Top
Published in: BMC Ophthalmology 1/2019

Open Access 01-12-2019 | Cataract | Research article

Efficacy of an ocular bandage contact lens for the treatment of dry eye after phacoemulsification

Authors: Xiaofan Chen, Rongdi Yuan, Min Sun, Xiao Chen, Sen Lin, Jian Ye, Chunlin Chen

Published in: BMC Ophthalmology | Issue 1/2019

Login to get access

Abstract

Background

To evaluate the safety and efficacy of a bandage contact lens for alleviating dry eye discomfort after phacoemulsification.

Methods

In this prospective, controlled study, 60 age-related cataract patients with mild Meibomian gland dysfunction (MGD) were randomized to treatment with an ocular bandage contact lens (BCL) (n = 30) or to an untreated control group (n = 30) after phacoemulsification and intraocular lens implantation. The Ocular Surface Disease Index (OSDI) questionnaire, evaluation of subjective symptoms and evaluation of the best-corrected visual acuity (BCVA) were conducted preoperatively and postoperatively on days 1, 7, 14, 30 and 90. The tear breakup time (TBUT), Schirmer test with anesthesia, and fluorescein staining scores were measured preoperatively and postoperatively on days 7, 14, 30 and 90.

Results

There were no significant differences with respect to the BCVA between the groups at any time point. For the comparison of the OSDI, subjective evaluation scores, TBUT and fluorescein staining, statistically significant improvements were noted in the BCL group, especially on days 7 and 14 (P < 0.001, P < 0.001; P = 0.031, P = 0.009; P = 0.021, P = 0.028; and P = 0.03, P = 0.032, respectively). The Schirmer test results did not significantly change postoperatively.

Conclusions

A BCL can improve tear film stability and lessen dry eye discomfort immediately after phacoemulsification.

Trial registration

Current Controlled Trials ChiCTR-INR-16008863 (Date of registration: 20 July 2016).
Literature
1.
go back to reference Sutu C, Fukuoka H, Afshari NA. Mechanisms and management of dry eye in cataract surgery patients. Curr Opin Ophthalmol. 2016;27(1):24–30.CrossRef Sutu C, Fukuoka H, Afshari NA. Mechanisms and management of dry eye in cataract surgery patients. Curr Opin Ophthalmol. 2016;27(1):24–30.CrossRef
2.
go back to reference Lee JH, Song IS, Kim KL, Yoon SY. Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery. J Ophthalmol. 2016;2016:8150757.PubMedPubMedCentral Lee JH, Song IS, Kim KL, Yoon SY. Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery. J Ophthalmol. 2016;2016:8150757.PubMedPubMedCentral
3.
go back to reference Cho YK, Kim MS. Dry eye after cataract surgery and associated intraoperative risk factors. Korean J Ophthalmol. 2009;23(2):65–73.CrossRef Cho YK, Kim MS. Dry eye after cataract surgery and associated intraoperative risk factors. Korean J Ophthalmol. 2009;23(2):65–73.CrossRef
4.
go back to reference Hardten DR. Dry eye disease in patients after cataract. surgery. 2008;27(7):855. Hardten DR. Dry eye disease in patients after cataract. surgery. 2008;27(7):855.
5.
go back to reference Szakats I, Sebestyen M, Toth E, Purebl G. Dry Eye Symptoms, Patient-Reported Visual Functioning, and Health Anxiety Influencing Patient Satisfaction After Cataract Surgery. Curr Eye Res. 2017;42(6):832–6.CrossRef Szakats I, Sebestyen M, Toth E, Purebl G. Dry Eye Symptoms, Patient-Reported Visual Functioning, and Health Anxiety Influencing Patient Satisfaction After Cataract Surgery. Curr Eye Res. 2017;42(6):832–6.CrossRef
6.
go back to reference Han KE, Yoon SC, Ahn JM, Nam SM, Stulting RD, Kim EK, et al. Evaluation of dry eye and meibomian gland dysfunction after cataract surgery. Am J Ophthalmol. 2014;157(6):1144–50.e1.CrossRef Han KE, Yoon SC, Ahn JM, Nam SM, Stulting RD, Kim EK, et al. Evaluation of dry eye and meibomian gland dysfunction after cataract surgery. Am J Ophthalmol. 2014;157(6):1144–50.e1.CrossRef
7.
go back to reference Yeotikar NS, Zhu H, Markoulli M, Nichols KK, Naduvilath T, Papas EB. Functional and Morphologic Changes of Meibomian Glands in an Asymptomatic Adult Population. Invest Ophthalmol Vis Sci. 2016;57(10):3996–4007.CrossRef Yeotikar NS, Zhu H, Markoulli M, Nichols KK, Naduvilath T, Papas EB. Functional and Morphologic Changes of Meibomian Glands in an Asymptomatic Adult Population. Invest Ophthalmol Vis Sci. 2016;57(10):3996–4007.CrossRef
8.
go back to reference Den S, Shimizu K, Ikeda T, Tsubota K, Shimmura S, Shimazaki J. Association between meibomian gland changes and aging, sex, or tear function. Cornea. 2006;25(6):651–5.CrossRef Den S, Shimizu K, Ikeda T, Tsubota K, Shimmura S, Shimazaki J. Association between meibomian gland changes and aging, sex, or tear function. Cornea. 2006;25(6):651–5.CrossRef
9.
go back to reference Arita R, Itoh K, Inoue K, Amano S. Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population. Ophthalmology. 2008;115(5):911–5.CrossRef Arita R, Itoh K, Inoue K, Amano S. Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population. Ophthalmology. 2008;115(5):911–5.CrossRef
10.
go back to reference Jung JW, Han SJ, Nam SM, Kim TI, Kim EK, Seo KY. Meibomian gland dysfunction and tear cytokines after cataract surgery according to preoperative meibomian gland status. Clin Exp Ophthalmol. 2016;44(7):555–62.CrossRef Jung JW, Han SJ, Nam SM, Kim TI, Kim EK, Seo KY. Meibomian gland dysfunction and tear cytokines after cataract surgery according to preoperative meibomian gland status. Clin Exp Ophthalmol. 2016;44(7):555–62.CrossRef
11.
go back to reference Choi JA, Chung SH. Combined application of autologous serum eye drops and silicone hydrogel lenses for the treatment of persistent epithelial defects. Eye Contact Lens. 2011;37(6):370–3.CrossRef Choi JA, Chung SH. Combined application of autologous serum eye drops and silicone hydrogel lenses for the treatment of persistent epithelial defects. Eye Contact Lens. 2011;37(6):370–3.CrossRef
12.
go back to reference Lee YK, Lin YC, Tsai SH, Chen WL, Chen YM. Therapeutic outcomes of combined topical autologous serum eye drops with silicone-hydrogel soft contact lenses in the treatment of corneal persistent epithelial defects: A preliminary study. Cont Lens Anterior Eye. 2016;39(6):425–30.CrossRef Lee YK, Lin YC, Tsai SH, Chen WL, Chen YM. Therapeutic outcomes of combined topical autologous serum eye drops with silicone-hydrogel soft contact lenses in the treatment of corneal persistent epithelial defects: A preliminary study. Cont Lens Anterior Eye. 2016;39(6):425–30.CrossRef
13.
go back to reference Lloyd-McKernan A, Simo ML, O’Dwyer V. The effect of previous soft contact lens wear on corneal refractive surgery outcomes. Cont Lens Anterior Eye. 2017;40(5):301–10.CrossRef Lloyd-McKernan A, Simo ML, O’Dwyer V. The effect of previous soft contact lens wear on corneal refractive surgery outcomes. Cont Lens Anterior Eye. 2017;40(5):301–10.CrossRef
14.
go back to reference Pinero DP, Perez-Cambrodi RJ, Ruiz-Fortes P, Blanes-Mompo FJ. New-generation hybrid contact lens for the management of extreme irregularity in a thin cornea after unsuccessful excimer laser refractive surgery. Eye Contact Lens. 2014;40(3):e16–20.CrossRef Pinero DP, Perez-Cambrodi RJ, Ruiz-Fortes P, Blanes-Mompo FJ. New-generation hybrid contact lens for the management of extreme irregularity in a thin cornea after unsuccessful excimer laser refractive surgery. Eye Contact Lens. 2014;40(3):e16–20.CrossRef
15.
go back to reference Kanonidou E, Chatziralli IP, Praidou A, Konidaris V. Contact lens usage characteristics among young individuals and their perception regarding future refractive surgery. Graefes Arch Clin Exp Ophthalmol. 2011;249(2):307–8.CrossRef Kanonidou E, Chatziralli IP, Praidou A, Konidaris V. Contact lens usage characteristics among young individuals and their perception regarding future refractive surgery. Graefes Arch Clin Exp Ophthalmol. 2011;249(2):307–8.CrossRef
16.
go back to reference Dell SJ, Hovanesian JA, Raizman MB, Crandall AS, Doane J, Snyder M, et al. Randomized comparison of postoperative use of hydrogel ocular bandage and collagen corneal shield for wound protection and patient tolerability after cataract surgery. J Cataract Refract Surg. 2011;37(1):113–21.CrossRef Dell SJ, Hovanesian JA, Raizman MB, Crandall AS, Doane J, Snyder M, et al. Randomized comparison of postoperative use of hydrogel ocular bandage and collagen corneal shield for wound protection and patient tolerability after cataract surgery. J Cataract Refract Surg. 2011;37(1):113–21.CrossRef
17.
go back to reference Sykakis E, Karim R, Kinsella M, Bhogal M, Patel S, Parmar DN. Study of fluid ingress through clear corneal incisions following phacoemulsification with or without the use of a hydrogel ocular bandage: a prospective comparative randomised study. Acta Ophthalmol. 2014;92(8):e663–6.CrossRef Sykakis E, Karim R, Kinsella M, Bhogal M, Patel S, Parmar DN. Study of fluid ingress through clear corneal incisions following phacoemulsification with or without the use of a hydrogel ocular bandage: a prospective comparative randomised study. Acta Ophthalmol. 2014;92(8):e663–6.CrossRef
18.
go back to reference Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615–21.CrossRef Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615–21.CrossRef
19.
go back to reference Yao K, Bao Y, Ye J, Lu Y, Bi H, Tang X, et al. Efficacy of 1% carboxymethylcellulose sodium for treating dry eye after phacoemulsification: results from a multicenter, open-label, randomized, controlled study. Bmc Ophthalmol. 2015;15:28.CrossRef Yao K, Bao Y, Ye J, Lu Y, Bi H, Tang X, et al. Efficacy of 1% carboxymethylcellulose sodium for treating dry eye after phacoemulsification: results from a multicenter, open-label, randomized, controlled study. Bmc Ophthalmol. 2015;15:28.CrossRef
20.
go back to reference Li XM, Hu L, Hu J, Wang W. Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Cornea. 2007;26(9 Suppl 1):S16–20.CrossRef Li XM, Hu L, Hu J, Wang W. Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Cornea. 2007;26(9 Suppl 1):S16–20.CrossRef
21.
go back to reference Park Y, Hwang HB, Kim HS. Observation of Influence of Cataract Surgery on the Ocular Surface. Plos One. 2016;11(10):e0152460.CrossRef Park Y, Hwang HB, Kim HS. Observation of Influence of Cataract Surgery on the Ocular Surface. Plos One. 2016;11(10):e0152460.CrossRef
22.
go back to reference Liang Q, Dong Z, Wang N. Perioperative ocular surface evaluation and management in meibomian gland dysfunction patients undergoing cataract surgery. Zhonghua Yan Ke Za Zhi. 2014;50(4):244–6 In Chinese.PubMed Liang Q, Dong Z, Wang N. Perioperative ocular surface evaluation and management in meibomian gland dysfunction patients undergoing cataract surgery. Zhonghua Yan Ke Za Zhi. 2014;50(4):244–6 In Chinese.PubMed
Metadata
Title
Efficacy of an ocular bandage contact lens for the treatment of dry eye after phacoemulsification
Authors
Xiaofan Chen
Rongdi Yuan
Min Sun
Xiao Chen
Sen Lin
Jian Ye
Chunlin Chen
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Cataract
Published in
BMC Ophthalmology / Issue 1/2019
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-018-1023-8

Other articles of this Issue 1/2019

BMC Ophthalmology 1/2019 Go to the issue