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Open Access 01-12-2018 | Research article

Refractory macular hole repaired by autologous retinal graft and blood clot

Authors: An-Lun Wu, Lan-Hsin Chuang, Nan-Kai Wang, Kuan-Jen Chen, Laura Liu, Ling Yeung, Tun-Lu Chen, Yih-Shiou Hwang, Wei-Chi Wu, Chi-Chun Lai

Published in: BMC Ophthalmology | Issue 1/2018

Abstract

Background

To evaluate the surgical technique using autologous retinal graft (ARG) and autologous blood clot (ABC) for the management of refractory macular holes (MHs).

Methods

This study was a retrospective, consecutive, interventional case series. Six eyes of 6 patients who underwent vitrectomy combined with ARG and ABC for the treatment of refractory MH were reviewed. Visual and anatomic outcomes were evaluated.

Results

The mean age was 59.0 ± 9.9 years. All cases had multiple vitreoretinal procedures including vitrectomy and gas fluid exchange before patient presentation. The average numbers of vitrectomies were 2.3 ± 0.5, and those of gas fluid exchange were 3 ± 1.7. Closure of the macular hole was achieved in four (66.7%) cases at last follow-up. The mean follow-up time was 25.2 ± 15.6 months. The averaged BCVA before and after 12 months of the surgery improved from 20/591 to 20/244.

Conclusions

This surgical technique using ARG and ABC provide an option for the treatment of refractory MHs.

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Title: Refractory macular hole repaired by autologous retinal graft and blood clot
Authors: An-Lun Wu
Lan-Hsin Chuang
Nan-Kai Wang
Kuan-Jen Chen
Laura Liu
Ling Yeung
Tun-Lu Chen
Yih-Shiou Hwang
Wei-Chi Wu
Chi-Chun Lai
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2018
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-018-0898-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Refractory macular hole repaired by autologous retinal graft and blood clot

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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