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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2018

Open Access 01-12-2018 | Research article

Evaluating inner retinal dimples after inner limiting membrane removal using multimodal imaging of optical coherence tomography

Authors: Jingjing Liu, Yiye Chen, Shiyuan Wang, Xiang Zhang, Peiquan Zhao

Published in: BMC Ophthalmology | Issue 1/2018

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Abstract

Background

To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitreoretinal interface conditions.

Methods

The data of 38 eyes in 35 patients who underwent surgery for LMH, and FTMH were retrospectively studied. The presence of postoperative inner retinal dimples was judged by a combination of en face OCT layer images and cross-sectional images. The demographic and clinical characteristics of eyes with and without inner retinal defects were compared to identify factors involved in the formation of the defects.

Results

Inner retinal defects were found in 26 eyes (68%) after surgery. They appeared on the en face OCT ILM layer images as multiple dark spots limited to the ILM peeling area, and corresponded to dimples or pitting of inner retinal layers on cross-sectional OCT images. In 5 cases (19%), apparent progression of inner retinal defects was observed on the en face OCT images as increasing numbers and sizes of the dark spots, which seemed to follow an eccentric growth pattern starting from the central macula. In addition, highly myopic eyes were found to be associated with the formation of more severe inner retinal defects.

Conclusions

Multiple imaging modes of en face spectral-domain OCT provide comprehensive information about the appearance of inner retinal dimples. High myopic eyes seem to develop more severe inner retinal defects after ILM peeling.
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Metadata
Title
Evaluating inner retinal dimples after inner limiting membrane removal using multimodal imaging of optical coherence tomography
Authors
Jingjing Liu
Yiye Chen
Shiyuan Wang
Xiang Zhang
Peiquan Zhao
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2018
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-018-0828-9

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