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Published in: BMC Ophthalmology 1/2018

Open Access 01-12-2018 | Research article

Cataract surgery in patients with corneal opacities

Authors: Yi-Ju Ho, Chi-Chin Sun, Hung-Chi Chen

Published in: BMC Ophthalmology | Issue 1/2018

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Abstract

Background

Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities.

Methods

This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having received phacoemulsification with IOL insertion without any ancillary techniques were enrolled. The primary study outcome measures were uncorrected and best corrected visual acuity (BCVA), and complications. Backscatters of corneal scar lesions were evaluated by slit lamp-based haze grading, Scheimpflug Pentacam and anterior segment optical coherence tomography (ASOCT). Visual outcomes after cataract surgeries and improvement range were used to determine the safety and efficacy of cataract surgery for our patients.

Results

All patients underwent uneventful capsulorhexis and phacoemulsification. The mean age was 72.22 ± 10.1 years, and the mean follow-up period was 18.57 ± 15.42 months. The mean BCVA significantly improved from 1.45 ± 0.65 preoperatively to 0.94 ± 0.55 logMAR postoperatively (p < 0.001), and the number of eyes with a BCVA of 20/100 or better increased from 4 to 14. Complications included corneal edema in two eyes and reactivation of the previous corneal pathology in five eyes. Four eyes did not achieve an improvement in visual acuity after surgery, which may have been due to co-existing ocular co-morbidities. Both Pentacam corneal densitometry and ASOCT demonstrated no significant correlations with final visual outcome. However, a statistically significant relationship between the severity of corneal opacity and improvement range in BCVA (r = − 0.782, P = 0.001) was found by our OCT grading method.

Conclusions

Phacoemulsification and IOL implantation in selected cases of coexisting cataracts and corneal opacities is safe that can provide suboptimal but long-term vision when penetrating keratoplasty is not possible or at high-risk of graft failure. ASOCT is a simple tool to predict visual outcomes after cataract surgery in opacified corneas.
Literature
1.
2.
go back to reference Javadi MA, Feizi S, Moein HR. Simultaneous penetrating keratoplasty and cataract surgery. J Ophthalmic Vis Res. 2013;8(1):39–46.PubMedPubMedCentral Javadi MA, Feizi S, Moein HR. Simultaneous penetrating keratoplasty and cataract surgery. J Ophthalmic Vis Res. 2013;8(1):39–46.PubMedPubMedCentral
3.
go back to reference Davis EA, et al. Refractive and keratometric results after the triple procedure: experience with early and late suture removal. Ophthalmology. 1998;105(4):624–30.CrossRefPubMed Davis EA, et al. Refractive and keratometric results after the triple procedure: experience with early and late suture removal. Ophthalmology. 1998;105(4):624–30.CrossRefPubMed
4.
go back to reference Shimmura S, et al. Corneal opacity and cataract: triple procedure versus secondary approach. Cornea. 2003;22(3):234–8.CrossRefPubMed Shimmura S, et al. Corneal opacity and cataract: triple procedure versus secondary approach. Cornea. 2003;22(3):234–8.CrossRefPubMed
5.
go back to reference Moore JE, Herath GD, Sharma A. Continuous curvilinear capsulorhexis with use of an endoscope. J Cataract Refract Surg. 2004;30(5):960–3.CrossRefPubMed Moore JE, Herath GD, Sharma A. Continuous curvilinear capsulorhexis with use of an endoscope. J Cataract Refract Surg. 2004;30(5):960–3.CrossRefPubMed
6.
go back to reference Chylack LT Jr, et al. The Lens opacities classification system III. The longitudinal study of cataract study group. Arch Ophthalmol. 1993;111(6):831–6.CrossRefPubMed Chylack LT Jr, et al. The Lens opacities classification system III. The longitudinal study of cataract study group. Arch Ophthalmol. 1993;111(6):831–6.CrossRefPubMed
7.
go back to reference Farjo AA, Meyer RF, Farjo QA. Phacoemulsification in eyes with corneal opacification. J Cataract Refract Surg. 2003;29(2):242–5.CrossRefPubMed Farjo AA, Meyer RF, Farjo QA. Phacoemulsification in eyes with corneal opacification. J Cataract Refract Surg. 2003;29(2):242–5.CrossRefPubMed
8.
go back to reference Titiyal JS, et al. Dye-assisted small incision cataract surgery in eyes with cataract and coexisting corneal opacity. Eye (Lond). 2006;20(3):386–8.CrossRef Titiyal JS, et al. Dye-assisted small incision cataract surgery in eyes with cataract and coexisting corneal opacity. Eye (Lond). 2006;20(3):386–8.CrossRef
9.
go back to reference Chowdhury PK, Raj SM, Vasavada AR. Inadvertent staining of the vitreous with trypan blue. J Cataract Refract Surg. 2004;30(1):274–6.CrossRefPubMed Chowdhury PK, Raj SM, Vasavada AR. Inadvertent staining of the vitreous with trypan blue. J Cataract Refract Surg. 2004;30(1):274–6.CrossRefPubMed
10.
go back to reference Al Sabti K, Raizada S, Al Abduljalil T. Cataract surgery assisted by anterior endoscopy. Br J Ophthalmol. 2009;93(4):531–4.CrossRefPubMed Al Sabti K, Raizada S, Al Abduljalil T. Cataract surgery assisted by anterior endoscopy. Br J Ophthalmol. 2009;93(4):531–4.CrossRefPubMed
11.
go back to reference Chang YS, et al. Indocyanine green-assisted phacoemulsification in cases of complicated or simple advanced cataracts. J Formos Med Assoc. 2008;107(9):710–9.CrossRefPubMed Chang YS, et al. Indocyanine green-assisted phacoemulsification in cases of complicated or simple advanced cataracts. J Formos Med Assoc. 2008;107(9):710–9.CrossRefPubMed
12.
go back to reference Panda A, Krishna SN, Dada T. Outcome of phacoemulsification in eyes with cataract and cornea opacity partially obscuring the pupillary area. Nepal J Ophthalmol. 2012;4(2):217–23.PubMed Panda A, Krishna SN, Dada T. Outcome of phacoemulsification in eyes with cataract and cornea opacity partially obscuring the pupillary area. Nepal J Ophthalmol. 2012;4(2):217–23.PubMed
13.
go back to reference Wirbelauer C, et al. Histopathological correlation of corneal diseases with optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2002;240(9):727–34.CrossRefPubMed Wirbelauer C, et al. Histopathological correlation of corneal diseases with optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2002;240(9):727–34.CrossRefPubMed
14.
go back to reference Campos M, et al. Clinical follow-up of phototherapeutic keratectomy for treatment of corneal opacities. Am J Ophthalmol. 1993;115(4):433–40.CrossRefPubMed Campos M, et al. Clinical follow-up of phototherapeutic keratectomy for treatment of corneal opacities. Am J Ophthalmol. 1993;115(4):433–40.CrossRefPubMed
15.
go back to reference Wang J, Simpson TL, Fonn D. Objective measurements of corneal light-backscatter during corneal swelling, by optical coherence tomography. Invest Ophthalmol Vis Sci. 2004;45(10):3493–8.CrossRefPubMed Wang J, Simpson TL, Fonn D. Objective measurements of corneal light-backscatter during corneal swelling, by optical coherence tomography. Invest Ophthalmol Vis Sci. 2004;45(10):3493–8.CrossRefPubMed
16.
go back to reference Wirbelauer C, Pham DT. Imaging and quantification of calcified corneal lesions with optical coherence tomography. Cornea. 2004;23(5):439–42.CrossRefPubMed Wirbelauer C, Pham DT. Imaging and quantification of calcified corneal lesions with optical coherence tomography. Cornea. 2004;23(5):439–42.CrossRefPubMed
17.
go back to reference Kamiya K, et al. Effect of light scattering and higher-order aberrations on visual performance in eyes with granular corneal dystrophy. Sci Rep. 2016;6:24677.CrossRefPubMedPubMedCentral Kamiya K, et al. Effect of light scattering and higher-order aberrations on visual performance in eyes with granular corneal dystrophy. Sci Rep. 2016;6:24677.CrossRefPubMedPubMedCentral
18.
go back to reference Kamiya K, et al. Effect of scattering and aberrations on visual acuity for band keratopathy. Optom Vis Sci. 2017;94(11):1009–14.CrossRefPubMed Kamiya K, et al. Effect of scattering and aberrations on visual acuity for band keratopathy. Optom Vis Sci. 2017;94(11):1009–14.CrossRefPubMed
19.
go back to reference Ni Dhubhghaill S, et al. Normative values for corneal densitometry analysis by Scheimpflug optical assessment. Invest Ophthalmol Vis Sci. 2014;55(1):162–8.CrossRefPubMed Ni Dhubhghaill S, et al. Normative values for corneal densitometry analysis by Scheimpflug optical assessment. Invest Ophthalmol Vis Sci. 2014;55(1):162–8.CrossRefPubMed
20.
go back to reference Kim TI, et al. Determination of treatment strategies for granular corneal dystrophy type 2 using Fourier-domain optical coherence tomography. Br J Ophthalmol. 2010;94(3):341–5.CrossRefPubMed Kim TI, et al. Determination of treatment strategies for granular corneal dystrophy type 2 using Fourier-domain optical coherence tomography. Br J Ophthalmol. 2010;94(3):341–5.CrossRefPubMed
21.
go back to reference Mori H, et al. Three-dimensional optical coherence tomography-guided phototherapeutic keratectomy for granular corneal dystrophy. Cornea. 2009;28(8):944–7.CrossRefPubMed Mori H, et al. Three-dimensional optical coherence tomography-guided phototherapeutic keratectomy for granular corneal dystrophy. Cornea. 2009;28(8):944–7.CrossRefPubMed
22.
go back to reference Dick HB, et al. Long-term endothelial cell loss following phacoemulsification through a temporal clear corneal incision. J Cataract Refract Surg. 1996;22(1):63–71.CrossRefPubMed Dick HB, et al. Long-term endothelial cell loss following phacoemulsification through a temporal clear corneal incision. J Cataract Refract Surg. 1996;22(1):63–71.CrossRefPubMed
23.
go back to reference Kim EC, Kim MS. A comparison of endothelial cell loss after phacoemulsification in penetrating keratoplasty patients and normal patients. Cornea. 2010;29(5):510–5.CrossRefPubMed Kim EC, Kim MS. A comparison of endothelial cell loss after phacoemulsification in penetrating keratoplasty patients and normal patients. Cornea. 2010;29(5):510–5.CrossRefPubMed
24.
go back to reference Muraine MC, Collet A, Brasseur G. Deep lamellar keratoplasty combined with cataract surgery. Arch Ophthalmol. 2002;120(6):812–5.CrossRefPubMed Muraine MC, Collet A, Brasseur G. Deep lamellar keratoplasty combined with cataract surgery. Arch Ophthalmol. 2002;120(6):812–5.CrossRefPubMed
25.
go back to reference Srinivasan S, Kiire C, Lyall D. Chandelier anterior chamber endoillumination-assisted phacoemulsification in eyes with corneal opacities. Clin Exp Ophthalmol. 2013;41(5):515–7.CrossRefPubMed Srinivasan S, Kiire C, Lyall D. Chandelier anterior chamber endoillumination-assisted phacoemulsification in eyes with corneal opacities. Clin Exp Ophthalmol. 2013;41(5):515–7.CrossRefPubMed
26.
go back to reference Greene JB, Mian SI. Cataract surgery in patients with corneal disease. Curr Opin Ophthalmol. 2013;24(1):9–14.CrossRefPubMed Greene JB, Mian SI. Cataract surgery in patients with corneal disease. Curr Opin Ophthalmol. 2013;24(1):9–14.CrossRefPubMed
27.
go back to reference Sainz de la Maza M, Tauber J, Foster CS. Cataract surgery in ocular cicatricial pemphigoid. Ophthalmology. 1988;95(4):481–6.CrossRefPubMed Sainz de la Maza M, Tauber J, Foster CS. Cataract surgery in ocular cicatricial pemphigoid. Ophthalmology. 1988;95(4):481–6.CrossRefPubMed
28.
go back to reference Geerling G, Dart JK. Management and outcome of cataract surgery in ocular cicatricial pemphigoid. Graefes Arch Clin Exp Ophthalmol. 2000;238(2):112–8.CrossRefPubMed Geerling G, Dart JK. Management and outcome of cataract surgery in ocular cicatricial pemphigoid. Graefes Arch Clin Exp Ophthalmol. 2000;238(2):112–8.CrossRefPubMed
29.
go back to reference Puranik CJ, et al. Outcomes of cataract surgery in ocular cicatricial pemphigoid. Ocul Immunol Inflamm. 2013;21(6):449–54.CrossRefPubMed Puranik CJ, et al. Outcomes of cataract surgery in ocular cicatricial pemphigoid. Ocul Immunol Inflamm. 2013;21(6):449–54.CrossRefPubMed
30.
go back to reference Barequet IS, Wasserzug Y. Herpes simplex keratitis after cataract surgery. Cornea. 2007;26(5):615–7.CrossRefPubMed Barequet IS, Wasserzug Y. Herpes simplex keratitis after cataract surgery. Cornea. 2007;26(5):615–7.CrossRefPubMed
31.
go back to reference Majander AS, et al. Anterior segment optical coherence tomography in congenital corneal opacities. Ophthalmology. 2012;119(12):2450–7.CrossRefPubMed Majander AS, et al. Anterior segment optical coherence tomography in congenital corneal opacities. Ophthalmology. 2012;119(12):2450–7.CrossRefPubMed
32.
go back to reference Garzon N, et al. Corneal densitometry and its correlation with age, pachymetry, corneal curvature, and refraction. Int Ophthalmol. 2017;37(6):1263–8.CrossRefPubMed Garzon N, et al. Corneal densitometry and its correlation with age, pachymetry, corneal curvature, and refraction. Int Ophthalmol. 2017;37(6):1263–8.CrossRefPubMed
Metadata
Title
Cataract surgery in patients with corneal opacities
Authors
Yi-Ju Ho
Chi-Chin Sun
Hung-Chi Chen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2018
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-018-0765-7

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