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Open Access 01-12-2017 | Case report

A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy

Authors: Keigo Kakurai, Maiko Hayashi, Kanako Yamada, Norihiko Ishizaki, Yumiko Yonemoto, Seita Morishita, Ryohsuke Kohmoto, Takaki Sato, Teruyo Kida, Tsunehiko Ikeda

Published in: BMC Ophthalmology | Issue 1/2017

Abstract

Background

To report the case of a patient with pseudoxanthoma elasticum (PXE) and proliferative diabetic retinopathy (PDR), and discuss the relationship between PXE and diabetic retinopathy (DR).

Case presentation

A 47-year-old man with PXE presented with angioid streaks and DR in both eyes, and bilateral panretinal photocoagulation was performed for treatment. Vitrectomy had previously been performed in his right eye for vitreous hemorrhage due to PDR. Systemic findings included multiple, discrete, symmetrical, small yellow papules bilaterally in the axilla and inguinal region. Examination on presentation showed vitreous hemorrhage in his left eye, and vitrectomy was performed for treatment. Intraoperative findings showed fibrovascular membrane around the optic disc and vascular arcade. A mottled fundus (peau d’orange appearance) associated with angioid streaks was also present, yet there was no evident choroidal neovascularization (CNV). The postoperative course was satisfactory, and corrected visual acuity improved from 0.02 to 0.7 diopters.

Conclusion

Despite the peau d’orange appearance in both eyes of this case, no CNV was evident. The vitreous hemorrhage was thus attributed to PDR. Moreover, we reviewed the published literature and discuss the relationship between PXE and DR.

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Title: A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy
Authors: Keigo Kakurai
Maiko Hayashi
Kanako Yamada
Norihiko Ishizaki
Yumiko Yonemoto
Seita Morishita
Ryohsuke Kohmoto
Takaki Sato
Teruyo Kida
Tsunehiko Ikeda
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2017
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-017-0569-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy

Abstract

Background

Case presentation

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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