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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2017

Open Access 01-12-2017 | Case report

Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases

Authors: Saiqun Li, Yuqing Deng, Caiyuan Du, Haixiang Huang, Jing Zhong, Ling Chen, Bowen Wang, Jin Yuan

Published in: BMC Ophthalmology | Issue 1/2017

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Abstract

Background

Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial.

Case presentation

We present two cases of Mooren’s ulcer that were treated using conjunctival flap in an attempt to prevent further corneal perforation at their local hospital. A rapid acceleration in ulcer progression was observed after a conjunctival flap was applied. Ultimately, the two patients underwent corneal transplantation, which required the postoperative use of topical immunosuppressants and resulted in a final cure. In the current report, we also discussed this incorrect surgical choice via a review of conventional interventions that are used to treat Mooren’s ulcer.

Conclusions

These two cases demonstrate that keratoplasty combined with topical immunosuppressants is effective in treating Mooren’s ulcer. Application of conjunctival flaps or autografting could promote progression of ulceration in Mooren’s ulcers.
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Metadata
Title
Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases
Authors
Saiqun Li
Yuqing Deng
Caiyuan Du
Haixiang Huang
Jing Zhong
Ling Chen
Bowen Wang
Jin Yuan
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2017
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-017-0488-1

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