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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2017

Open Access 01-12-2017 | Research article

The observation during small incision lenticule extraction for myopia with corneal opacity

Authors: Shaowei Zhang, Haipeng Xu, Ke Zheng, Jing Zhao, Weijun Jian, Meiyan Li, Xingtao Zhou

Published in: BMC Ophthalmology | Issue 1/2017

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Abstract

Background

To evaluate the feasibility and efficacy of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal opacity.

Methods

To evaluate the treatment of myopia with corneal opacity, 9 patients (4 males, 5 females) who underwent SMILE were enrolled in this prospective clinical study. One eye of each patient was treated. The results of laser scanning and lenticule extraction were observed during the surgery, and the surgical videos were again reviewed after surgery. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and spherical equivalence (SE) were noted at 1 month after surgery. The depth and density of the corneal opacities were measured by anterior segment optical coherence tomography (AS-OCT) and the Pentacam anterior eye segment analyzer.

Results

All procedures were uneventful and no intraoperative complications were observed. At 1 month after surgery, the UDVA of all patients was 20/25 or better and no patients lost Snellen lines. The mean safety and efficacy indexes were 1.10 ± 0.24 and 1.08 ± 0.16, respectively, at 1 month postoperatively. The mean postoperative spherical equivalent was 0.27 ± 0.23 diopter (D). All eyes were within ±0.75 D and 8 eyes (88.9%) were within ±0.50 D. There was no eccentric corneal topography or abnormal morphology in the corneal caps. The corneal opacities of all patients were within the optical zone. The mean preoperative depths in the deepest areas of corneal opacity were 152 ± 38 μm (range: 86–217 μm); at 1 month after surgery (P < .01), they were 117 ± 28 μm (range: 86–189 μm). The preoperative maximum density of corneal opacity was 48.5 ± 20.7 (range: 20.4 to 85.8); at 1 month after surgery (P > .05), it was 49.8 ± 26.7 (range: 19.8 to 82.5) at 1 month after surgery.

Conclusion

Patients with corneal opacity can be successfully treated with the SMILE operation. The short-term outcome was good, however the long-term results need further study.

Trial registration

The trial registration number: ChiCTR-ONRC-13003114, Date of Last Refreshed on: 2016-01-27, Date of registration on 2013-03-17(retrospectively registered).
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Metadata
Title
The observation during small incision lenticule extraction for myopia with corneal opacity
Authors
Shaowei Zhang
Haipeng Xu
Ke Zheng
Jing Zhao
Weijun Jian
Meiyan Li
Xingtao Zhou
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2017
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-017-0474-7

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