Skip to main content
Top
Published in: BMC Ophthalmology 1/2017

Open Access 01-12-2017 | Case report

Extensive bilateral corneal edema 6 weeks after cataract surgery: Keratopathy due to Asclepias physocarpa: a case report

Authors: Kazuki Matsuura, Shiro Hatta, Yuki Terasaka, Yoshitsugu Inoue

Published in: BMC Ophthalmology | Issue 1/2017

Login to get access

Abstract

Background

Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection.

Case presentation

A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 weeks after uneventful cataract surgery. We observed extensive hyperemia and corneal stromal edema with Descemet’s folds in both eyes.
After obtaining a detailed patient history, we diagnosed plant toxin-induced corneal edema due to Asclepias physocarpa, which can induce corneal edema by inhibiting the Na+/K+ ATPase activity of the corneal endothelium.
Antimicrobial and steroid eye drops and an oral steroid were prescribed accordingly. Symptons began to improve on day 3 and had almost completely resolved by day 6. At 1 month, the patient had fully recovered without any sequelae.

Conclusion

The correct diagnosis was possible in the present case as symptoms were bilateral and the patient was able to report his potential exposure to plant toxins. However, if the symptoms had been unilateral and the patient had been unaware of these toxins, he may have undergone unnecessary surgical interventions to treat non-existent postoperative endophthalmitis.
Literature
2.
go back to reference Chakraborty S, Siegenthaler J, Büchi ER. Corneal edema due to Asclepias curassavica. Arch Ophthalmol. 1995;113:974–5.CrossRefPubMed Chakraborty S, Siegenthaler J, Büchi ER. Corneal edema due to Asclepias curassavica. Arch Ophthalmol. 1995;113:974–5.CrossRefPubMed
4.
go back to reference Zhang RR, Tian HY, Tan YF, Chung TY, Sun XH, Xia X, Ye WC, Middleton DA, Fedosova N, Esmann M, Tzen JT, Jiang RW. Structures, chemotaxonomic significance, cytotoxic and Na(+), K(+)-ATPase inhibitory activities of new cardenolides from Asclepias curassavica. Org Biomol Chem. 2014;12:8919–29. doi:10.1039/c4ob01545b.CrossRefPubMed Zhang RR, Tian HY, Tan YF, Chung TY, Sun XH, Xia X, Ye WC, Middleton DA, Fedosova N, Esmann M, Tzen JT, Jiang RW. Structures, chemotaxonomic significance, cytotoxic and Na(+), K(+)-ATPase inhibitory activities of new cardenolides from Asclepias curassavica. Org Biomol Chem. 2014;12:8919–29. doi:10.​1039/​c4ob01545b.CrossRefPubMed
6.
go back to reference Eke T, Al-Husainy S, Raynor MK. The spectrum of ocular inflammation caused by euphorbia plant sap. Arch Ophthalmol. 2000;118:13–6.CrossRefPubMed Eke T, Al-Husainy S, Raynor MK. The spectrum of ocular inflammation caused by euphorbia plant sap. Arch Ophthalmol. 2000;118:13–6.CrossRefPubMed
Metadata
Title
Extensive bilateral corneal edema 6 weeks after cataract surgery: Keratopathy due to Asclepias physocarpa: a case report
Authors
Kazuki Matsuura
Shiro Hatta
Yuki Terasaka
Yoshitsugu Inoue
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2017
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-017-0400-z

Other articles of this Issue 1/2017

BMC Ophthalmology 1/2017 Go to the issue