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Open Access 01-12-2020 | Gestational Diabetes | Research article

Burden, associated risk factors and adverse outcomes of gestational diabetes mellitus in twin pregnancies in Al Ain, UAE

Authors: Juma Alkaabi, Raya Almazrouei, Taoufik Zoubeidi, Fatema M. Alkaabi, Fatima Rashid Alkendi, Amel Eisa Almiri, Charu Sharma, Abdul-Kader Souid, Nasloon Ali, Luai A. Ahmed

Published in: BMC Pregnancy and Childbirth | Issue 1/2020

Abstract

Background

Gestational diabetes mellitus (GDM) in singleton pregnancies represent a high-risk scenario. The incidence, associated factors and outcomes of GDM in twin pregnancies is not known in the UAE.

Methods

This was five years retrospective analysis of hospital records of twin pregnancies in the city of Al Ain, Abu Dhabi, UAE. Relevant data with regards to the pregnancy, maternal and birth outcomes and incidence of GDM was extracted from two major hospitals in the city. Regression models assessed the relationship between socio-demographic and pregnancy-related variables and GDM, and the associations between GDM and maternal and fetal outcomes at birth.

Results

A total of 404 women and their neonates were part of this study. The study population had a mean age of 30.1 (SD: 5.3), overweight or obese (66.5%) and were majority multiparous (66.6%). High incidence of GDM in twin pregnancies (27.0%). While there were no statistical differences in outcomes of the neonates, GDM mothers were older (OR: 1.09, 95% CI: 1.06–1.4) and heavier (aOR: 1.02, 95% CI: 1.00 -1.04). They were also likely to have had GDM in their previous pregnancies (aOR: 7.37, 95% CI: 2.76–19.73). The prognosis of mothers with twin pregnancies and GDM lead to an independent and increased odds of cesarean section (aOR: 2.34, 95% CI: 1.03–5.30) and hospitalization during pregnancy (aOR: 1.60, 95% CI: 1.16–2.20).

Conclusion

More than a quarter of women with twin pregnancies were diagnosed with GDM. GDM was associated with some adverse pregnancy outcomes but not fetal outcomes in this population. More studies are needed to further investigate these associations and the management of GDM in twin pregnancies.

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Title: Burden, associated risk factors and adverse outcomes of gestational diabetes mellitus in twin pregnancies in Al Ain, UAE
Authors: Juma Alkaabi
Raya Almazrouei
Taoufik Zoubeidi
Fatema M. Alkaabi
Fatima Rashid Alkendi
Amel Eisa Almiri
Charu Sharma
Abdul-Kader Souid
Nasloon Ali
Luai A. Ahmed
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Gestational Diabetes
Sectio Ceasarea
Gestational Diabetes
Sectio Caesarea
Published in: BMC Pregnancy and Childbirth / Issue 1/2020
Electronic ISSN: 1471-2393
DOI: https://doi.org/10.1186/s12884-020-03289-w

At a glance: The STEP trials

Springer Medicine

Burden, associated risk factors and adverse outcomes of gestational diabetes mellitus in twin pregnancies in Al Ain, UAE

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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