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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2020

Open Access 01-12-2020 | Septicemia | Research article

Outcome of uterine rupture and associated factors in Yirgalem general and teaching hospital, southern Ethiopia: a cross-sectional study

Authors: Achamyelesh Gebretsadik, Hailemichael Hagos, Kebede Tefera

Published in: BMC Pregnancy and Childbirth | Issue 1/2020

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Abstract

Background

The occurrence of uterine rupture has dropped significantly in high income countries. It continues, however, to be a major public and clinical health problem in low income countries including Ethiopia. Aim of this study was to assess management outcomes of uterine rupture and associated factors in Yirgalem General and Teaching Hospital in South Ethiopia.

Methods

Institution-based cross-sectional study was conducted to examine medical records of women with uterine rupture between January 1, 2012, and Decem”ber 31, 2017. Data were collected based on a checklist. Descriptive statistics and logistic regression analyses were performed.

Results

Incidence of uterine rupture was 345 in 13,500 live births (25.5 in 1000 live births) in the study period. Of these, 331 cases were included. Poor maternal outcome occurred in 224 (67.7%) women. There were 13 (3.7%) maternal deaths and 320 (96.7%) stillbirths. Wound site infection (131; 39.6%) and anemia (129; 39%) were the most common post-operative complications. Prolonged duration of labor (more than 24 h) (adjusted odds ratio (aOR) 3.6; 95% CI 1.7–7.4), women with sepsis on admission (aOR 2.9; 95% CI 1.4–6.1), hemoglobin level < 7 g/dl prior to surgical intervention (aOR 4.5; 95% CI 1.1–17.8), delayed surgical intervention after hospitalization (4 h or more before surgery) (aOR 3.8; 95% CI 1.8–8), women who did not receive blood transfusion (aOR 4.0; 95% CI 2.1–7.9) and prolonged intraoperative time (aOR 5.5; 95% CI 2.8–10.8) were all factors associated with poor maternal outcome of uterine rupture.

Conclusion

Poor maternal outcome of uterine rupture was high in the study area as compared to other studies. Proper management of anemia, prompt surgical treatment, proper labor progress monitoring, surgical skills, improved infection prevention, maximizing blood transfusion availability and improving the quality of maternal healthcare all play a significant role in reducing uterine rupture and enhancing the chance of good outcomes.
Literature
1.
Nicolás I. Uterine rupture and pregnancy current vision: scientific evidence and consensus with the patient. Reproductive Immunol. 2016;3(19):1–4.
2.
den Akker V, Mwagomba B, Irlam J, Van Roosmalen J. Using audit to reduce the incidence of uterine rupture in a Malawian District hospital. Int J Gynecol Obstet. 2009;107:289–94.CrossRef
3.
World Health Organization. Trends in Maternal Mortality: 1990 to 2015 Estimates by WHO, UNICEF, UNFPA. In: World Bank Group and the United Nations Population Division. Geneva: World health Organization; 2015.
4.
Gülmezoglu A, Say L, Betrán A, Villar J, Piaggio G. World Health Organization systemic review of maternal mortality and morbidity methodological issues and challenges. BMC Med Res Methodol. 2004;4(16):5–8.
5.
Mengistie H, Amenu D, Mengistie B. Maternal and perinatal outcomes of uterine rupture patient are among Mothers who delivered at Mizan Aman General Hospital, A five year retrospective hospital based study. MOJ Womens Health. 2016;2(1):13–23.
6.
Aliyu S, Yizengaw T. Prevalence and associated factors of uterine rupture during labor among women who delivered in Debre Markos hospital north West Ethiopia. Intern Med. 2016;6(222):3–6.
7.
Marie T, Mulat A, Eshetie T. Associated factors and outcomes of uterine rupture at Suhul general hospital, shire town, north West Tigray. Ethiopia Int J Gynecol Obstet. 2017;2017:4–7.
8.
Centeral statistical agency Ethiopia. Maternal and perinatal morbidity and mortality. Ethiopia Demographic and Health Survey; 2016.
9.
Hofmeyr GJ, Say L, Gulmezoglu AM. WHO systematic review of maternal mortality and morbidity: the prevalence of uterine rupture. BJOG. 2005;112(9):1221–8.CrossRef
10.
Berhan Y, Berhan A. Causes of maternal mortality in Ethiopia: a significant decline in abortion related death. Ethiop J Health Sci. 2014;24:15–28.CrossRef
11.
Vladimir R, Aruna M, Sambit M, Tahir M. A case series of uterine rupture: lessons to be learned for future clinical practice. J Obstet Gynaecol India. 2013;62(6):665–73.
12.
Yemane Y, Giza W. Assessement of the associated factors, management and complications of uterine rupture at Mizan Tepi University teaching hospital. Mizan Aman Town Health Sci J. 2017;11(3):1–9.
13.
Chibber R, El-Saleh E, Al Fadhli R, Al Jassar W, Al Harmi J. Uterine rupture and subsequent pregnancy outcome – how safe is it? A 25-year study. J Matern Fetal Neonatal Med. 2010;23(5):421–4.CrossRef
14.
Dadi T, Yarinabab T. Estimates of uterine rupture bad outcomes using propensity score and determinants of uterine rupture in Mizan-Tepi University teaching hospital. J Pregnancy. 2017;25(6):1–10.CrossRef
15.
Mbamara S, Obiechina N, Eleje G. An analysis of uterine rupture at the Nnamdi Azikiwe University teaching hospital Nnewi, Southeast Nigeria. Niger J Clin Pract. 2012;15(4):448–52.CrossRef
16.
Gebre S, Negassi A. Risk factors for uterine rupture in Suhul general hospital case control study. Electronic J Bio. 2017;13(3):198–202.
17.
Aziz N, Yousfani S. Analysis of uterine rupture at university teaching hospital Pakistan. Pak J Med Sci. 2015;31(4):920–92.PubMedPubMedCentral
18.
Sunanda N, Priya R. A two-year analysis of uterine rupture in pregnancy. Int J Reprod Contracept Obstet Gynecol. 2016;5:3983–6.
19.
Vandenberghe G, Bloemenkamp K, Berlage S, et al. The international network of obstetric survey systems study of uterine rupture: a descriptive multi-country population-based study. BJOG. 2019;126:370–81.CrossRef
20.
Astatikie G, Kebede M, Limenh M. Maternal and fetal outcomes of uterine rupture and associated with maternal death secondary to uterine rupture. BMC Pregnancy Child Birth. 2017;17(117):42–9.
21.
Mukasa PK, Kabakyenga J, Senkungu JK, Ngonzi J, Kyalimpa M, van Roosmalen J. Uterine rupture in a teaching hospital in Mbarara, western Uganda, and unmatched case- control study. Reprod Health. 2013;29(10):29.CrossRef
22.
Sinha M, Gupta R, Gupta P, et al. Uterine rupture: a seven year review at a tertiary Care Hospital in new Delhi. India Indian J Community Med. 2016;41(1):45–9.CrossRef
23.
Chamiso B. Rupture of the pregnant uterus in Shashemene general hospital. Ethiopian Med J. 2010;33(4):251–7.
24.
Mathai M. The partograph for the prevention of obstructed labor. Clin Obstet Gynecol. 2009;52(2):256–69.CrossRef
25.
Kidanto H, Mwampagatwa I, van Roosmalen J. Uterine rupture: a retrospective analysis of causes, complications and management outcomes at Muhimbili National Hospital in Dar Es Salaam, Tanzania. Tanzan J Health Res. 2012;14(3):1–9.
Metadata
Title
Outcome of uterine rupture and associated factors in Yirgalem general and teaching hospital, southern Ethiopia: a cross-sectional study
Authors
Achamyelesh Gebretsadik
Hailemichael Hagos
Kebede Tefera
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2020
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-020-02950-8

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