Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2018

Open Access 01-12-2018 | Research article

Excessive gestational weight gain in accordance with the IOM criteria and the risk of hypertensive disorders of pregnancy: a meta-analysis

Authors: Min Ren, Hanying Li, Wei Cai, Xiulong Niu, Wenjie Ji, Zhuoli Zhang, Jianmin Niu, Xin Zhou, Yuming Li

Published in: BMC Pregnancy and Childbirth | Issue 1/2018

Login to get access

Abstract

Background

Excessive gestational weight gain (GWG) is a potential risk factor for hypertensive disorders of pregnancy (HDP).

Methods

We systematically reviewed three electronic databases for relevant articles published in English: PubMed, EMBASE and Web of Science. The Newcastle-Ottawa Scale was used to assess study quality. Random-effects meta-analyses were performed to supply a pooled estimation of the OR comparing the risk of HDP among healthy pregnant women with and without excessive GWG.

Results

The pooled estimation for the association between excessive GWG and the risk of HDPs yielded an odds ratio (OR) of 1.79 (95% CI: 1.61–1.99). A subgroup analysis showed that women who had excessive GWG were more likely to have an HDP (OR 1.82; 95% CI 1.53–2.17), preeclampsia (OR 1.92; 95% CI 1.36–2.72), or gestational hypertension (OR 1.67; 95% CI 1.43–1.95). The pooled estimation for the association between excessive GWG and the risk of HDPs among pregestational normal weight women yielded an OR of 1.57 (95% CI 1.26–1.96). A subgroup analysis showed that women who had excessive GWG were more likely to have HDP (OR 1.45; 95% CI 1.09–1.92) or gestational hypertension (OR 1.51; 95% CI 1.22–1.86). The summary ORs of pre-gestational underweight women and pre-gestational overweight and obese women were 2.17 (95% CI 1.56–3.02) and 1.32 (95% CI 1.08–1.63), respectively.

Conclusions

The findings of this study suggest that excessive GWG in accordance with the IOM recommendations influences the rate of HDP.
Appendix
Available only for authorised users
Literature
1.
Naderi S, Tsai SA, Khandelwal A. Hypertensive disorders of pregnancy. Curr Atheroscler Rep. 2017;19(3):15.CrossRefPubMed
2.
3.
Mol BWJ, Roberts CT, Thangaratinam S, Magee LA, de Groot CJM, Hofmeyr GJ. Pre-eclampsia. Lancet. 2016;387(10022):999–1011.CrossRefPubMed
4.
Osol G, Bernstein I. Preeclampsia and maternal cardiovascular disease: consequence or predisposition? J Vasc Res. 2014;51(4):290–304.CrossRefPubMed
5.
Rich-Edwards JW, Fraser A, Lawlor DA, Catov JM. Pregnancy characteristics and women's future cardiovascular health: an underused opportunity to improve women's health? Epidemiol Rev. 2014;36:57–70.CrossRefPubMed
6.
Lei Q, Zhou X, Zhou YH, Mai CY, Hou MM, Lv LJ, Duan DM, Wen JY, Lin XH, Wang PP, et al. Prehypertension during normotensive pregnancy and postpartum clustering of Cardiometabolic risk factors: a prospective cohort study. Hypertension. 2016;68(2):455–63.CrossRefPubMed
7.
Gaillard R, Steegers EA, Hofman A, Jaddoe VW. Associations of maternal obesity with blood pressure and the risks of gestational hypertensive disorders. The generation R study. J Hypertens. 2011;29(5):937–44.CrossRefPubMed
8.
Gilmore LA, Klempel-Donchenko M, Redman LM. Pregnancy as a window to future health: excessive gestational weight gain and obesity. Semin Perinatol. 2015;39(4):296–303.CrossRefPubMedPubMedCentral
9.
Waring ME, Moore Simas TA, Liao X. Gestational weight gain within recommended ranges in consecutive pregnancies: a retrospective cohort study. Midwifery. 2013;29(5):550–6.CrossRefPubMed
10.
Lei Q, Zhou X, Duan DM, Lv LJ, Lin XH, Ji WJ, Cai W, Zhang Z, Li YM, Niu JM. Trimester-Specific Weight Gain and Midpregnancy Diastolic Blood Pressure Rebound During Normotensive Pregnancy. Hypertension. 2017;70(4):804–12.CrossRefPubMed
11.
Heude B, Thiébaugeorges O, Goua V, Forhan A, Kaminski M, Foliguet B, Schweitzer M, Magnin G, Charles MA. EDEN Mother-Child Cohort Study GroupPre-pregnancy body mass index and weight gain during pregnancy: relations with gestational diabetes and hypertension, and birth outcomes. Matern Child Health J. 2012;16(2):355–63.CrossRefPubMedPubMedCentral
12.
Institute of Medicine (US) Committee on Nutritional Status During Pregnancy and Lactation. Nutrition During Pregnancy: Part I weight gain: part II nutrient supplements. Washington (DC): National Academies Press (US); 1990.
13.
Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines. In: Rasmussen KM, Yaktine AL, editors. Weight gain during pregnancy: Reexamining the Guidelines. Washington (DC): National Academies Press (US); 2009.
14.
Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283(15):2008–12.CrossRefPubMed
15.
Hung TH, Hsieh TT. Pregestational body mass index, gestational weight gain, and risks for adverse pregnancy outcomes among Taiwanese women: a retrospective cohort study. Taiwan J Obstet Gynecol. 2016;55(4):575–81.CrossRefPubMed
16.
Tanaka T, Ashihara K, Nakamura M, Kanda T, Fujita D, Yamashita Y, Terai Y, Kamegai H, Ohmichi M. Associations between the pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in Japanese women. J Obstet Gynaecol Res. 2014;40(5):1296–303.CrossRefPubMed
17.
Liu L, Hong Z, Zhang L. Associations of prepregnancy body mass index and gestational weight gain with pregnancy outcomes in nulliparous women delivering single live babies. Sci Rep. 2015;5:12863.CrossRefPubMedPubMedCentral
18.
Li C, Liu Y, Zhang W. Joint and independent associations of gestational weight gain and pre-pregnancy body mass index with outcomes of pregnancy in Chinese women: a retrospective cohort study. PLoS One. 2015;10(8):e0136850.CrossRefPubMedPubMedCentral
19.
Enomoto K, Aoki S, Toma R, Fujiwara K, Sakamaki K, Hirahara F. Pregnancy outcomes based on pre-pregnancy body mass index in Japanese women. PLoS One. 2016;11(6):e0157081.CrossRefPubMedPubMedCentral
20.
Chung JG, Taylor RS, Thompson JM, Anderson NH, Dekker GA, Kenny LC, McCowan LM, SCOPE Consortium. Gestational weight gain and adverse pregnancy outcomes in a nulliparous cohort. Eur J Obstet Gynecol Reprod Biol. 2013;167(2):149–53.CrossRefPubMed
21.
Chasan-Taber L, Silveira M, Waring ME, Pekow P, Braun B, Manson JE, Solomon CG, Markenson G. Gestational weight gain, body mass index, and risk of hypertensive disorders of pregnancy in a predominantly Puerto Rican population. Matern Child Health J. 2016;20(9):1804–13.CrossRefPubMedPubMedCentral
22.
Johnson J, Clifton RG, Roberts JM, Myatt L, Hauth JC, Spong CY, Varner MW, Wapner RJ, Thorp JM Jr, Mercer BM, et al. Pregnancy outcomes with weight gain above or below the 2009 Institute of Medicine guidelines. Obstet Gynecol. 2013;121(5):969–75.CrossRefPubMedPubMedCentral
23.
Hannaford KE, Tuuli MG, Odibo L, Macones GA, Odibo AO. Gestational weight gain: association with adverse pregnancy outcomes. Am J Perinatol. 2017;34(2):147–54.PubMed
24.
Fouelifack FY, Fouedjio JH, Fouogue JT, Sando Z, Fouelifa LD, Mbu RE. Associations of body mass index and gestational weight gain with term pregnancy outcomes in urban Cameroon: a retrospective cohort study in a tertiary hospital. BMC Res Notes. 2015;8:806.CrossRefPubMedPubMedCentral
25.
Li N, Liu E, Guo J, Pan L, Li B, Wang P, Liu J, Wang Y, Liu G, Baccarelli AA, et al. Maternal prepregnancy body mass index and gestational weight gain on pregnancy outcomes. PLoS One. 2013;8(12):e82310.CrossRefPubMedPubMedCentral
26.
Zhou A, Xiong C, Hu R, Zhang Y, Bassig BA, Triche E, Yang S, Qiu L, Zhang Y, Yao C, et al. Pre-pregnancy BMI, gestational weight gain, and the risk of hypertensive disorders of pregnancy: a cohort study in Wuhan, China. PLoS One. 2015;10(8):e0136291.CrossRefPubMedPubMedCentral
27.
de la Torre L, Flick AA, Istwan N, Rhea D, Cordova Y, Dieguez C, Desch C, González-Quintero VH. The effect of new antepartum weight gain guidelines and prepregnancy body mass index on the development of pregnancy-related hypertension. Am J Perinatol. 2011;28(4):285–92.CrossRefPubMed
28.
Cook DA, Reed DA. Appraising the quality of medical education research methods: the medical education research study quality instrument and the Newcastle–Ottawa scale-education. Eur J Epidemiol Acad Med. 2015;90(8):1067–76.
29.
Macdonald-Wallis C, Tilling K, Fraser A, Nelson SM, Lawlor DA. Gestational weight gain as a risk factor for hypertensive disorders of pregnancy. Am J Obstet Gynecol. 2013;209(4):327. e1–17CrossRefPubMedPubMedCentral
30.
Chen Z, Du J, Shao L, Zheng L, Wu M, Ai M, Zhang Y. Prepregnancy body mass index, gestational weight gain, and pregnancy outcomes in China. Int J Gynaecol Obstet. 2010;109(1):41–4.CrossRefPubMed
31.
Choi SK, Park IY, Shin JC. The effects of pre-pregnancy body mass index and gestational weight gain on perinatal outcomes in Korean women: a retrospective cohort study. Reprod Biol Endocrinol. 2011;9:6.CrossRefPubMedPubMedCentral
32.
Ray WG, Phyllis AA, Gary C, Lee AG, Marshall DL, Donald MN, James MR, Edward JR, Baha MS, Sandra JT. National High Blood Pressure Education Program Working Group Report on High Blood Pressure in Pregnancy. Am J Obstet Gynecol. 1990;163(5 Pt 1):1691–712.
33.
Shin D, Chung H, Weatherspoon L, Song WO. Validity of prepregnancy weight status estimated from self-reported height and weight. Matern Child Health J. 2014;18(7):1667–74.CrossRefPubMed
34.
Oken E, Taveras EM, Kleinman KP, Rich-Edwards JW, Gillman MW. Gestational weight gain and child adiposity at age 3 years. Am J Obstet Gynecol. 2007;196(4):322.e1–8.CrossRef
Metadata
Title
Excessive gestational weight gain in accordance with the IOM criteria and the risk of hypertensive disorders of pregnancy: a meta-analysis
Authors
Min Ren
Hanying Li
Wei Cai
Xiulong Niu
Wenjie Ji
Zhuoli Zhang
Jianmin Niu
Xin Zhou
Yuming Li
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2018
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-018-1922-y

Other articles of this Issue 1/2018

BMC Pregnancy and Childbirth 1/2018 Go to the issue

Research article

Childbirth preferences and related fears - comparison between Norway and Israel

Research article

Tolerability of trivalent inactivated influenza vaccine among pregnant women, 2015

Research article

Association of intimate partner violence during pregnancy, prenatal depression, and adverse birth outcomes in Wuhan, China

Case report

Spontaneous uterine rupture and surgical repair at 21 weeks gestation with progression to live birth: a case report

Study protocol

Kuopio birth cohort – design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child

Research article

How do informal information sources influence women’s decision-making for birth? A meta-synthesis of qualitative studies