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BMC Pregnancy and Childbirth

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Open Access 01-12-2016 | Research article

Approach to the sonographic evaluation of fetal ventriculomegaly at 11 to 14 weeks gestation

Authors: Gwendolin Manegold-Brauer, Anton Oseledchyk, Anne Floeck, Christoph Berg, Ulrich Gembruch, Annegret Geipel

Published in: BMC Pregnancy and Childbirth | Issue 1/2016

Abstract

Background

The aim of the study was to report the prevalence and associated findings of fetal ventriculomegaly between 11 + 0 and 13 + 6 gestational weeks and to evaluate a sonographic approach to classify first trimester ventriculomegaly in the standard axial plane used for biparietal diameter (BPD) measurement.

Methods

The ratio between choroid plexus and lateral ventricle diameter (PDVDR), between the choroid plexus and lateral ventricle length (PLVLR) and between the choroid plexus and lateral ventricle area (PAVAR) were calculated from stored 2D images of the axial head plane in 100 normal fetuses and 17 fetuses with ventriculomegaly.

Results

The PDVDR, the PLVLR and the PAVAR were below the 5^th percentile in 82.4 %, 94.1 % and 94.1 % of the cases with ventriculomegaly. Ventriculomegaly was isolated in 29.4 % and associated with further anomalies in 70.6 % at the initial evaluation. The mean PLVLR in euploid compared to aneuploid fetuses was significantly lower (0.40 versus 0.53 (p = 0.0332)).

Conclusions

The measurements of PDVDR, PLVLR and PAVAR are helpful to objectify ventriculomegaly at 11–14 gestational weeks. The PLVLR and PAVAR were superior to PDVDR, since there seems to be rather shrinkage of the choroid plexus than an increased width of the lateral ventricles in the first trimester.

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Title: Approach to the sonographic evaluation of fetal ventriculomegaly at 11 to 14 weeks gestation
Authors: Gwendolin Manegold-Brauer
Anton Oseledchyk
Anne Floeck
Christoph Berg
Ulrich Gembruch
Annegret Geipel
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Pregnancy and Childbirth / Issue 1/2016
Electronic ISSN: 1471-2393
DOI: https://doi.org/10.1186/s12884-016-0797-z

At a glance: The STEP trials

Springer Medicine

Approach to the sonographic evaluation of fetal ventriculomegaly at 11 to 14 weeks gestation

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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