Skip to main content
Top
Published in: BMC Pregnancy and Childbirth 1/2014

Open Access 01-12-2014 | Research article

Prediction of uterine dehiscence using ultrasonographic parameters of cesarean section scar in the nonpregnant uterus: a prospective observational study

Authors: Michal Pomorski, Tomasz Fuchs, Mariusz Zimmer

Published in: BMC Pregnancy and Childbirth | Issue 1/2014

Login to get access

Abstract

Background

Every year 1.5 million cesarean section procedures are performed worldwide. As many women decide to get pregnant again, the population of pregnant women with a history of cesarean section is growing rapidly. For these women prediction of cesarean section scar performance is still a serious clinical problem.
The purpose of the study was to assess whether the parameters of cesarean section scar in the nonpregnant uterus as determined using ultrasound can be used to predict uterine dehiscence in the next pregnancy.

Methods

Starting in 2005, the study included 308 nonpregnant women with a history of low transverse cesarean section. The following ultrasonographic parameters of the cesarean section scar in the nonpregnant uterus were assessed: the residual myometrial thickness (RMT) and the width (W) and the depth (D) of the triangular hypoechoic scar niche. During 8 years of follow-up, 41 of these women were referred to our department for delivery. In all cases, a repeat cesarean section was performed and the lower uterine segment was assessed. Two independent statistical methods namely the logit model and Decision Tree analysis were used to determine the relation between the appearance of the cesarean section scar in the nonpregnat state and the performance of the scar in the next pregnancy.

Results

The logit model revealed that the D/RMT ratio showed significant correlation with cesarean section scar dehiscence (P-value of 0.007). Specifically, a D/RMT ratio value greater than 1.3035 indicated that the likelihood of dehiscence was greater than 50%. The Decision Tree analysis revealed that a diagnosis of dehiscence versus non-dehiscence could be based solely on one criterion, a D/RMT ratio of at least 0.785. The sensitivity of this method was 71%, and the specificity was 94%.

Conclusions

Assessment of the cesarean section scar in the nonpregant uterus can be used to predict the occurrence of scar dehiscence in the next pregnancy.
Appendix
Available only for authorised users
Literature
1.
go back to reference Guise JM, Eden K, Emeis C, Denman MA, Marshall N, Fu RR, Janik R, Nygren P, Walker M, McDonagh M: Vaginal birth after cesarean: new insights. Evid Rep Technol Assess (Full Rep). 2010, 191: 1-397. Guise JM, Eden K, Emeis C, Denman MA, Marshall N, Fu RR, Janik R, Nygren P, Walker M, McDonagh M: Vaginal birth after cesarean: new insights. Evid Rep Technol Assess (Full Rep). 2010, 191: 1-397.
2.
go back to reference Varner M: Cesarean scar imaging and prediction of subsequent obstetric complications. Clin Obstet Gynecol. 2012, 55: 988-996. 10.1097/GRF.0b013e318263c699.CrossRefPubMed Varner M: Cesarean scar imaging and prediction of subsequent obstetric complications. Clin Obstet Gynecol. 2012, 55: 988-996. 10.1097/GRF.0b013e318263c699.CrossRefPubMed
3.
go back to reference Zelop CM: Uterine rupture during a trial of labor after previous cesarean delivery. Clin Perinatol. 2011, 38: 277-284. 10.1016/j.clp.2011.03.009.CrossRefPubMed Zelop CM: Uterine rupture during a trial of labor after previous cesarean delivery. Clin Perinatol. 2011, 38: 277-284. 10.1016/j.clp.2011.03.009.CrossRefPubMed
4.
go back to reference Landon MB: Predicting uterine rupture in women undergoing trial of labor after prior cesarean delivery. Semin Perinatol. 2010, 34: 267-271. 10.1053/j.semperi.2010.03.005.CrossRefPubMed Landon MB: Predicting uterine rupture in women undergoing trial of labor after prior cesarean delivery. Semin Perinatol. 2010, 34: 267-271. 10.1053/j.semperi.2010.03.005.CrossRefPubMed
5.
go back to reference Vikhareva Osser O, Valentin L: Clinical importance of appearance of cesarean hysterotomy scar at transvaginal ultrasonography in nonpregnant women. Obstet Gynecol. 2011, 117: 525-532. 10.1097/AOG.0b013e318209abf0.CrossRefPubMed Vikhareva Osser O, Valentin L: Clinical importance of appearance of cesarean hysterotomy scar at transvaginal ultrasonography in nonpregnant women. Obstet Gynecol. 2011, 117: 525-532. 10.1097/AOG.0b013e318209abf0.CrossRefPubMed
6.
go back to reference Valentin L: Prediction of scar integrity and vaginal birth after caesarean delivery. Best Pract Res Clin Obstet Gynaecol. 2013, 27: 285-295. 10.1016/j.bpobgyn.2012.09.003.CrossRefPubMed Valentin L: Prediction of scar integrity and vaginal birth after caesarean delivery. Best Pract Res Clin Obstet Gynaecol. 2013, 27: 285-295. 10.1016/j.bpobgyn.2012.09.003.CrossRefPubMed
7.
go back to reference Rozenberg P, Goffinet F, Phillippe HJ, Nisand I: Ultrasonographic measurement of lower uterine segment to assess risk of defects of scarred uterus. Lancet. 1996, 347: 281-284. 10.1016/S0140-6736(96)90464-X.CrossRefPubMed Rozenberg P, Goffinet F, Phillippe HJ, Nisand I: Ultrasonographic measurement of lower uterine segment to assess risk of defects of scarred uterus. Lancet. 1996, 347: 281-284. 10.1016/S0140-6736(96)90464-X.CrossRefPubMed
8.
go back to reference Kok N, Wiersma IC, Opmeer BC, de Graaf IM, Mol BW, Pajkrt E: The ability of sonographic measurement of the lower uterine segment thickness to predict uterine rupture during a trial of labour in women with a previous Caesarean section: a meta-analysis. Ultrasound Obstet Gynecol. 2013, 42: 132-139. 10.1002/uog.12479.CrossRefPubMed Kok N, Wiersma IC, Opmeer BC, de Graaf IM, Mol BW, Pajkrt E: The ability of sonographic measurement of the lower uterine segment thickness to predict uterine rupture during a trial of labour in women with a previous Caesarean section: a meta-analysis. Ultrasound Obstet Gynecol. 2013, 42: 132-139. 10.1002/uog.12479.CrossRefPubMed
9.
go back to reference Jastrow N, Chaillet N, Roberge S, Morency AM, Lacasse Y, Bujold E: Sonographic lower uterine segment thickness and risk of uterine scar defect: a systematic review. J Obstet Gynaecol Can. 2010, 32: 321-327.CrossRefPubMed Jastrow N, Chaillet N, Roberge S, Morency AM, Lacasse Y, Bujold E: Sonographic lower uterine segment thickness and risk of uterine scar defect: a systematic review. J Obstet Gynaecol Can. 2010, 32: 321-327.CrossRefPubMed
10.
go back to reference Naji O, Abdallah Y, Bij De Vaate AJ, Smith A, Pexsters A, Stalder C, McIndoe A, Ghaem-Maghami S, Lees C, Brölmann HA, Huirne JA, Timmerman D, Bourne T: Standardized approach for imaging and measuring Cesarean section scars using ultrasonography. Ultrasound Obstet Gynecol. 2012, 39: 252-259. 10.1002/uog.10077.CrossRefPubMed Naji O, Abdallah Y, Bij De Vaate AJ, Smith A, Pexsters A, Stalder C, McIndoe A, Ghaem-Maghami S, Lees C, Brölmann HA, Huirne JA, Timmerman D, Bourne T: Standardized approach for imaging and measuring Cesarean section scars using ultrasonography. Ultrasound Obstet Gynecol. 2012, 39: 252-259. 10.1002/uog.10077.CrossRefPubMed
11.
go back to reference Naji O, Daemen A, Smith A, Abdallah Y, Saso S, Stalder C, Sayasneh A, McIndoe A, Ghaem-Maghami S, Timmerman D, Bourne T: Visibility and measurement of cesarean section scars in pregnancy: a reproducibility study. Ultrasound Obstet Gynecol. 2012, 40: 549-556. 10.1002/uog.11132.CrossRefPubMed Naji O, Daemen A, Smith A, Abdallah Y, Saso S, Stalder C, Sayasneh A, McIndoe A, Ghaem-Maghami S, Timmerman D, Bourne T: Visibility and measurement of cesarean section scars in pregnancy: a reproducibility study. Ultrasound Obstet Gynecol. 2012, 40: 549-556. 10.1002/uog.11132.CrossRefPubMed
12.
go back to reference Naji O, Daemen A, Smith A, Abdallah Y, Saso S, Stalder C, Sayasneh A, McIndoe A, Ghaem-Maghami S, Timmerman D, Bourne T: Changes in Cesarean section scar dimensions during pregnancy: a prospective longitudinal study. Ultrasound Obstet Gynecol. 2013, 41: 556-562. 10.1002/uog.12334.CrossRefPubMed Naji O, Daemen A, Smith A, Abdallah Y, Saso S, Stalder C, Sayasneh A, McIndoe A, Ghaem-Maghami S, Timmerman D, Bourne T: Changes in Cesarean section scar dimensions during pregnancy: a prospective longitudinal study. Ultrasound Obstet Gynecol. 2013, 41: 556-562. 10.1002/uog.12334.CrossRefPubMed
13.
go back to reference Peisner D: Instrumentation, Modality Selection and Documentation. Ultrasound in Gynecology. Edited by: Timor-Tritsch I, Goldstein SR. 2007, Churchill Livingstione, Philadelphia, 38-39. 2 Peisner D: Instrumentation, Modality Selection and Documentation. Ultrasound in Gynecology. Edited by: Timor-Tritsch I, Goldstein SR. 2007, Churchill Livingstione, Philadelphia, 38-39. 2
14.
go back to reference Armstrong V, Hansen WF, Van Voorhis BJ, Syrop CH: Detection of cesarean scars by transvaginal ultrasound. Obstet Gynecol. 2003, 101: 61-65. 10.1016/S0029-7844(02)02450-X.PubMed Armstrong V, Hansen WF, Van Voorhis BJ, Syrop CH: Detection of cesarean scars by transvaginal ultrasound. Obstet Gynecol. 2003, 101: 61-65. 10.1016/S0029-7844(02)02450-X.PubMed
15.
go back to reference Zimmer M, Pomorski M, Fuchs T, Tomialowicz M, Michniewicz J, Wiatrowski A, Mikolajczyk K: Ultrasonographic analysis of cesarean scars features in nonpregnant uterus. Ginekol Pol. 2007, 78: 842-846.PubMed Zimmer M, Pomorski M, Fuchs T, Tomialowicz M, Michniewicz J, Wiatrowski A, Mikolajczyk K: Ultrasonographic analysis of cesarean scars features in nonpregnant uterus. Ginekol Pol. 2007, 78: 842-846.PubMed
16.
go back to reference Ofili-Yebovi D, Ben-Nagi J, Sawyer E, Yazbek J, Lee C, Gonzalez J, Jurkovic D: Deficient lower-segment Cesarean section scars: prevalence and risk factors. Ultrasound Obstet Gynecol. 2008, 31: 72-77. 10.1002/uog.5200.CrossRefPubMed Ofili-Yebovi D, Ben-Nagi J, Sawyer E, Yazbek J, Lee C, Gonzalez J, Jurkovic D: Deficient lower-segment Cesarean section scars: prevalence and risk factors. Ultrasound Obstet Gynecol. 2008, 31: 72-77. 10.1002/uog.5200.CrossRefPubMed
17.
go back to reference Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA: The prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Cesarean section: a systematic review. Ultrasound Obstet Gynecol. 2014, 43: 372-382. 10.1002/uog.13199.CrossRefPubMed Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA: The prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Cesarean section: a systematic review. Ultrasound Obstet Gynecol. 2014, 43: 372-382. 10.1002/uog.13199.CrossRefPubMed
18.
go back to reference Zimmer M, Pomorski M, Fuchs T, Klosek A, Mikolajczyk K: Ultrasonographic parameters of cesarean scars in nonpregnant uterus [abstract]. Ultrasound Obstet Gynecol. 2008, 32: s428-10.1002/uog.6020.CrossRef Zimmer M, Pomorski M, Fuchs T, Klosek A, Mikolajczyk K: Ultrasonographic parameters of cesarean scars in nonpregnant uterus [abstract]. Ultrasound Obstet Gynecol. 2008, 32: s428-10.1002/uog.6020.CrossRef
19.
go back to reference Zimmer M, Pomorski M, Tomialowicz M, Wiatrowski A, Fuchs T, Milnerowicz-Nabzdyk E, Michniewicz J, Koziol A: Ultrasonographic features of Cesarean scars in non-pregnant uterus after single and multiple Cesarean sections [abstract]. Ultrasound Obstet Gynecol. 2011, 38 (S1): 38-10.1002/uog.9207. OC 20.04CrossRef Zimmer M, Pomorski M, Tomialowicz M, Wiatrowski A, Fuchs T, Milnerowicz-Nabzdyk E, Michniewicz J, Koziol A: Ultrasonographic features of Cesarean scars in non-pregnant uterus after single and multiple Cesarean sections [abstract]. Ultrasound Obstet Gynecol. 2011, 38 (S1): 38-10.1002/uog.9207. OC 20.04CrossRef
20.
go back to reference Polish Gynecological Society’s recommendations regarding cesarean section. Ginekol Pol. 2008, 79: 378-384. Polish Gynecological Society’s recommendations regarding cesarean section. Ginekol Pol. 2008, 79: 378-384.
21.
go back to reference Donnez O, Jadoul P, Squifflet J, Donnez J: Laparoscopic repair of wide and deep uterine scar dehiscence after cesarean section. Fertil Steril. 2008, 89: 974-980. 10.1016/j.fertnstert.2007.04.024.CrossRefPubMed Donnez O, Jadoul P, Squifflet J, Donnez J: Laparoscopic repair of wide and deep uterine scar dehiscence after cesarean section. Fertil Steril. 2008, 89: 974-980. 10.1016/j.fertnstert.2007.04.024.CrossRefPubMed
22.
go back to reference Marotta ML, Donnez J, Squifflet J, Jadoul P, Darii N, Donnez O: Laparoscopic repair of post-cesarean section uterine scar defects diagnosed in nonpregnant women. J Minim Invasive Gynecol. 2013, 20: 386-391. 10.1016/j.jmig.2012.12.006.CrossRefPubMed Marotta ML, Donnez J, Squifflet J, Jadoul P, Darii N, Donnez O: Laparoscopic repair of post-cesarean section uterine scar defects diagnosed in nonpregnant women. J Minim Invasive Gynecol. 2013, 20: 386-391. 10.1016/j.jmig.2012.12.006.CrossRefPubMed
Metadata
Title
Prediction of uterine dehiscence using ultrasonographic parameters of cesarean section scar in the nonpregnant uterus: a prospective observational study
Authors
Michal Pomorski
Tomasz Fuchs
Mariusz Zimmer
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2014
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-014-0365-3

Other articles of this Issue 1/2014

BMC Pregnancy and Childbirth 1/2014 Go to the issue