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Published in: BMC Neurology 1/2020

Open Access 01-12-2020 | Stroke | Research article

Two years’ experience of implementing a comprehensive telemedical stroke network comprising in mainly rural region: the Transregional Network for Stroke Intervention with Telemedicine (TRANSIT-Stroke)

Authors: Katharina M. A. Gabriel, Steffi Jírů-Hillmann, Peter Kraft, Udo Selig, Viktoria Rücker, Johannes Mühler, Klaus Dötter, Matthias Keidel, Hassan Soda, Alexandra Rascher, Rolf Schneider, Mathias Pfau, Roy Hoffmann, Joachim Stenzel, Mohamed Benghebrid, Tobias Goebel, Sebastian Doerck, Daniela Kramer, Karl Georg Haeusler, Jens Volkmann, Peter U. Heuschmann, Felix Fluri

Published in: BMC Neurology | Issue 1/2020

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Abstract

Background

Telemedicine improves the quality of acute stroke care in rural regions with limited access to specialized stroke care. We report the first 2 years’ experience of implementing a comprehensive telemedical stroke network comprising all levels of stroke care in a defined region.

Methods

The TRANSIT-Stroke network covers a mainly rural region in north-western Bavaria (Germany). All hospitals providing acute stroke care in this region participate in TRANSIT-Stroke, including four hospitals with a supra-regional certified stroke unit (SU) care (level III), three of those providing teleconsultation to two hospitals with a regional certified SU (level II) and five hospitals without specialized SU care (level I). For a two-year-period (01/2015 to 12/2016), data of eight of these hospitals were available; 13 evidence-based quality indicators (QIs) related to processes during hospitalisation were evaluated quarterly and compared according to predefined target values between level-I- and level-II/III-hospitals.

Results

Overall, 7881 patients were included (mean age 74.6 years ±12.8; 48.4% female). In level-II/III-hospitals adherence of all QIs to predefined targets was high ab initio. In level-I-hospitals, three patterns of QI-development were observed: a) high adherence ab initio (31%), mainly in secondary stroke prevention; b) improvement over time (44%), predominantly related to stroke specific diagnosis and in-hospital organization; c) no clear time trends (25%). Overall, 10 out of 13 QIs reached predefined target values of quality of care at the end of the observation period.

Conclusion

The implementation of the comprehensive TRANSIT-Stroke network resulted in an improvement of quality of care in level-I-hospitals.
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Literature
1.
go back to reference Alanee S, Dynda D, LeVault K, Mueller G, Sadowski D, Wilber A, Jenkins WD, Dynda M. Delivering kidney cancer care in rural central and southern Illinois: a telemedicine approach. Eur J Cancer Care. 2014;23(6):739–44.CrossRef Alanee S, Dynda D, LeVault K, Mueller G, Sadowski D, Wilber A, Jenkins WD, Dynda M. Delivering kidney cancer care in rural central and southern Illinois: a telemedicine approach. Eur J Cancer Care. 2014;23(6):739–44.CrossRef
2.
go back to reference Smith AC, Bensink M, Armfield N, Stillman J, Caffery L. Telemedicine and rural health care applications. J Postgrad Med. 2005;51(4):286–93.PubMed Smith AC, Bensink M, Armfield N, Stillman J, Caffery L. Telemedicine and rural health care applications. J Postgrad Med. 2005;51(4):286–93.PubMed
4.
go back to reference Veltkamp R. Akuttherapie des ischämischen Schlaganfalls. Edited by Kommission Leitlinien der Deutschen Gesellschaft für Neurologie, AWMF-Registernummer; 2012;17:030–046. Veltkamp R. Akuttherapie des ischämischen Schlaganfalls. Edited by Kommission Leitlinien der Deutschen Gesellschaft für Neurologie, AWMF-Registernummer; 2012;17:030–046.
5.
go back to reference Ringleb PA, Hamann GF, Röther J, Jansen O, Groden C, Veltkamp R. Akuttherapie des ischämischen Schlaganfalls – Ergänzung 2015. Rekanalisierende Therapie. Edited by Kommission Leitlinien der Deutschen Gesellschaft für Neurologie, AWMF-Registernummer; 2015;27:030–140. Ringleb PA, Hamann GF, Röther J, Jansen O, Groden C, Veltkamp R. Akuttherapie des ischämischen Schlaganfalls – Ergänzung 2015. Rekanalisierende Therapie. Edited by Kommission Leitlinien der Deutschen Gesellschaft für Neurologie, AWMF-Registernummer; 2015;27:030–140.
6.
go back to reference Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375(9727):1695–703.CrossRef Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375(9727):1695–703.CrossRef
7.
go back to reference Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med. 2018;378(1):11–21.CrossRef Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med. 2018;378(1):11–21.CrossRef
8.
go back to reference Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CBLM, Dippel DW, Campbell BC, Nogueira RG, Demchuk AM, Tomasello A, et al. Time to treatment with endovascular Thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA. 2016;316(12):1279–89.CrossRef Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CBLM, Dippel DW, Campbell BC, Nogueira RG, Demchuk AM, Tomasello A, et al. Time to treatment with endovascular Thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA. 2016;316(12):1279–89.CrossRef
9.
go back to reference Hubert GJ, Meretoja A, Audebert HJ, Tatlisumak T, Zeman F, Boy S, Haberl RL, Kaste M, Müller-Barna P. Stroke thrombolysis in a centralized and a decentralized system (Helsinki and Telemedical project for integrative stroke care network). Stroke. 2016;47(12):2999–3004.CrossRef Hubert GJ, Meretoja A, Audebert HJ, Tatlisumak T, Zeman F, Boy S, Haberl RL, Kaste M, Müller-Barna P. Stroke thrombolysis in a centralized and a decentralized system (Helsinki and Telemedical project for integrative stroke care network). Stroke. 2016;47(12):2999–3004.CrossRef
10.
go back to reference Meretoja A, Strbian D, Mustanoja S, Tatlisumak T, Lindsberg PJ, Kaste M. Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology. 2012;79(4):306–13.CrossRef Meretoja A, Strbian D, Mustanoja S, Tatlisumak T, Lindsberg PJ, Kaste M. Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology. 2012;79(4):306–13.CrossRef
11.
go back to reference Scott PA, Temovsky CJ, Lawrence K, Gudaitis E, Lowell MJ. Analysis of Canadian population with potential geographic access to intravenous thrombolysis for acute ischemic stroke. Stroke. 1998;29(11):2304–10.CrossRef Scott PA, Temovsky CJ, Lawrence K, Gudaitis E, Lowell MJ. Analysis of Canadian population with potential geographic access to intravenous thrombolysis for acute ischemic stroke. Stroke. 1998;29(11):2304–10.CrossRef
12.
go back to reference Wechsler LR, Demaerschalk BM, Schwamm LH, Adeoye OM, Audebert HJ, Fanale CV, Hess DC, Majersik JJ, Nystrom KV, Reeves MJ, et al. Telemedicine quality and outcomes in stroke: a scientific statement for Healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017;48(1):e3–e25.CrossRef Wechsler LR, Demaerschalk BM, Schwamm LH, Adeoye OM, Audebert HJ, Fanale CV, Hess DC, Majersik JJ, Nystrom KV, Reeves MJ, et al. Telemedicine quality and outcomes in stroke: a scientific statement for Healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017;48(1):e3–e25.CrossRef
13.
go back to reference Leira EC, Hess DC, Torner JC, Adams HP. Rural-urban differences in acute stroke management practices: a modifiable disparity. Arch Neurol. 2008;65(7):887–91.CrossRef Leira EC, Hess DC, Torner JC, Adams HP. Rural-urban differences in acute stroke management practices: a modifiable disparity. Arch Neurol. 2008;65(7):887–91.CrossRef
14.
go back to reference Sergeev AV. Racial and rural-urban disparities in stroke mortality outside the Stroke Belt. Ethn Dis. 2011;21(3):307–13.PubMed Sergeev AV. Racial and rural-urban disparities in stroke mortality outside the Stroke Belt. Ethn Dis. 2011;21(3):307–13.PubMed
15.
go back to reference Howard G, Kleindorfer DO, Cushman M, Long DL, Jasne A, Judd SE, Higginbotham JC, Howard VJ. Contributors to the excess stroke mortality in rural areas in the United States. Stroke. 2017;48(7):1773–8.CrossRef Howard G, Kleindorfer DO, Cushman M, Long DL, Jasne A, Judd SE, Higginbotham JC, Howard VJ. Contributors to the excess stroke mortality in rural areas in the United States. Stroke. 2017;48(7):1773–8.CrossRef
16.
go back to reference Callison RC, Leira EC. Strategies to improve acute stroke care of patients in rural and other geographically dispersed areas. Curr Treat Options Neurol. 2008;10(6):450–4.CrossRef Callison RC, Leira EC. Strategies to improve acute stroke care of patients in rural and other geographically dispersed areas. Curr Treat Options Neurol. 2008;10(6):450–4.CrossRef
17.
go back to reference Burgin WS, Staub L, Chan W, Wein TH, Felberg RA, Grotta JC, Demchuk AM, Hickenbottom SL, Morgenstern LB. Acute stroke care in non-urban emergency departments. Neurology. 2001;57(11):2006–12.CrossRef Burgin WS, Staub L, Chan W, Wein TH, Felberg RA, Grotta JC, Demchuk AM, Hickenbottom SL, Morgenstern LB. Acute stroke care in non-urban emergency departments. Neurology. 2001;57(11):2006–12.CrossRef
18.
go back to reference Koifman J, Hall R, Li S, Stamplecoski M, Fang J, Saltman AP, Kapral MK. The association between rural residence and stroke care and outcomes. J Neurol Sci. 2016;363:16–20.CrossRef Koifman J, Hall R, Li S, Stamplecoski M, Fang J, Saltman AP, Kapral MK. The association between rural residence and stroke care and outcomes. J Neurol Sci. 2016;363:16–20.CrossRef
19.
go back to reference Craig JJ, McConville JP, Patterson VH, Wootton R. Neurological examination is possible using telemedicine. J Telemed Telecare. 1999;5(3):177–81.CrossRef Craig JJ, McConville JP, Patterson VH, Wootton R. Neurological examination is possible using telemedicine. J Telemed Telecare. 1999;5(3):177–81.CrossRef
20.
go back to reference Rinde E, Nordrum I, Nymo BJ. Telemedicine in rural Norway. World Health Forum. 1993;14:71–7.PubMed Rinde E, Nordrum I, Nymo BJ. Telemedicine in rural Norway. World Health Forum. 1993;14:71–7.PubMed
21.
go back to reference Audebert HJ, Schenkel J, Heuschmann PU, Bogdahn U, Haberl RL. Effects of the implementation of a telemedical stroke network: the Telemedic pilot project for integrative stroke care (TEMPiS) in Bavaria, Germany. Lancet Neurol. 2006;5(9):742–8.CrossRef Audebert HJ, Schenkel J, Heuschmann PU, Bogdahn U, Haberl RL. Effects of the implementation of a telemedical stroke network: the Telemedic pilot project for integrative stroke care (TEMPiS) in Bavaria, Germany. Lancet Neurol. 2006;5(9):742–8.CrossRef
22.
go back to reference Audebert HJ, Schultes K, Tietz V, Heuschmann PU, Bogdahn U, Haberl RL. Schenkel J, on behalf of the Telemedical project for integrative stroke care (TEMPiS): Long-term effects of specialized stroke care with telemedicine support in community hospitals. Stroke. 2009;40(3):902–8.CrossRef Audebert HJ, Schultes K, Tietz V, Heuschmann PU, Bogdahn U, Haberl RL. Schenkel J, on behalf of the Telemedical project for integrative stroke care (TEMPiS): Long-term effects of specialized stroke care with telemedicine support in community hospitals. Stroke. 2009;40(3):902–8.CrossRef
23.
go back to reference Müller-Barna P, Hubert GJ, Boy S, Bogdahn U, Wiedmann S, Heuschmann PU, Audebert HJ. TeleStroke units serving as a model of Care in Rural Areas. 10-year experience of the TeleMedical project for integrative stroke care. Stroke. 2014;45(9):2739–44.CrossRef Müller-Barna P, Hubert GJ, Boy S, Bogdahn U, Wiedmann S, Heuschmann PU, Audebert HJ. TeleStroke units serving as a model of Care in Rural Areas. 10-year experience of the TeleMedical project for integrative stroke care. Stroke. 2014;45(9):2739–44.CrossRef
24.
go back to reference Wang S, Lee SB, Pardue C, Ramsingh D, Waller J, Gross H, Nichols FT, Hess DC, Adams RJ. Remote evaluation of acute ischemic stroke. Reliability of National Institutes of Health stroke scale via Telestroke. Stroke. 2003;34(10):e188–91.CrossRef Wang S, Lee SB, Pardue C, Ramsingh D, Waller J, Gross H, Nichols FT, Hess DC, Adams RJ. Remote evaluation of acute ischemic stroke. Reliability of National Institutes of Health stroke scale via Telestroke. Stroke. 2003;34(10):e188–91.CrossRef
25.
go back to reference Bodechtel U, Puetz V. Why Telestroke networks? Rationale, implementation and results of the stroke eastern Saxony network. J Neural Transm. 2013;120(1):43–7.CrossRef Bodechtel U, Puetz V. Why Telestroke networks? Rationale, implementation and results of the stroke eastern Saxony network. J Neural Transm. 2013;120(1):43–7.CrossRef
26.
go back to reference Audebert HJ, Kukla C, Clarmann von Claranau S, Kühn J, Vatankhah B, Schenkel J, Ickenstein GW, Haberl RL, Horn M. Telemedicine for safe and extended use of thrombolysis in stroke: the Telemedic pilot project for integrative stroke care (TEMPiS) in Bavaria. Stroke. 2005;36(2):287–91.CrossRef Audebert HJ, Kukla C, Clarmann von Claranau S, Kühn J, Vatankhah B, Schenkel J, Ickenstein GW, Haberl RL, Horn M. Telemedicine for safe and extended use of thrombolysis in stroke: the Telemedic pilot project for integrative stroke care (TEMPiS) in Bavaria. Stroke. 2005;36(2):287–91.CrossRef
27.
go back to reference Nguyen-Huynh MN, Klingman JG, Avins AL, Rao VA, Eaton A, Bhopale S, Kim AC, Morehouse JW, Flint AC, on behlaf of KPNC stroke FORCE team. Novel Telestroke program improves thrombolysis for acute stroke across 21 hospitals of an integrated Healthcare system. Stroke. 2018;49(1):133–9.CrossRef Nguyen-Huynh MN, Klingman JG, Avins AL, Rao VA, Eaton A, Bhopale S, Kim AC, Morehouse JW, Flint AC, on behlaf of KPNC stroke FORCE team. Novel Telestroke program improves thrombolysis for acute stroke across 21 hospitals of an integrated Healthcare system. Stroke. 2018;49(1):133–9.CrossRef
28.
go back to reference Pervez MA, Silva G, Masrur S, Betensky RA, Furie KL, Hidalgo R, Lima F, Rosenthal ES, Rost N, Viswanathan A, et al. Remote supervision of IV-tPA for acute ischemic stroke by telemedicine or telephone before transfer to a regional stroke center is feasible and safe. Stroke. 2010;41(1):e18–24.CrossRef Pervez MA, Silva G, Masrur S, Betensky RA, Furie KL, Hidalgo R, Lima F, Rosenthal ES, Rost N, Viswanathan A, et al. Remote supervision of IV-tPA for acute ischemic stroke by telemedicine or telephone before transfer to a regional stroke center is feasible and safe. Stroke. 2010;41(1):e18–24.CrossRef
29.
go back to reference Sanders KA, Patel R, Kiely JM, Gwynn MW, Johnston LH. Improving Telestroke treatment times in an expanding network of hospitals. J Stroke Cerebrovasc Dis. 2016;25(2):288–91.CrossRef Sanders KA, Patel R, Kiely JM, Gwynn MW, Johnston LH. Improving Telestroke treatment times in an expanding network of hospitals. J Stroke Cerebrovasc Dis. 2016;25(2):288–91.CrossRef
30.
go back to reference Schwab S, Vatankhah B, Kukla C, Hauchwitz M, Bogdahn U, Fürst A, Audebert HJ, Horn M, on behalf of the TEMPiS group. Long-term outcome after thrombolysis in telemedical stroke care. Neurology. 2007;69(9):898–903.CrossRef Schwab S, Vatankhah B, Kukla C, Hauchwitz M, Bogdahn U, Fürst A, Audebert HJ, Horn M, on behalf of the TEMPiS group. Long-term outcome after thrombolysis in telemedical stroke care. Neurology. 2007;69(9):898–903.CrossRef
33.
go back to reference Hillmann S, Wiedmann S, Rücker V, Berger K, Nabavi DG, Bruder I, Koennecke H-C, Seidel G, Misselwitz B, Janssen A et al: Stroke unit care in germany: the german stroke registers study group (ADSR). In: BMC Neurology. vol. 17; 2017: 8. Hillmann S, Wiedmann S, Rücker V, Berger K, Nabavi DG, Bruder I, Koennecke H-C, Seidel G, Misselwitz B, Janssen A et al: Stroke unit care in germany: the german stroke registers study group (ADSR). In: BMC Neurology. vol. 17; 2017: 8.
34.
go back to reference Nabavi DG, Ringelstein EB, Faiss J, Kessler C, Röther J, Busse O. Regionale und überregionale Stroke-Units in Deutschland. Nervenarzt. 2012;83(8):1039–52.CrossRef Nabavi DG, Ringelstein EB, Faiss J, Kessler C, Röther J, Busse O. Regionale und überregionale Stroke-Units in Deutschland. Nervenarzt. 2012;83(8):1039–52.CrossRef
35.
go back to reference Rauch S, Rauh J. Verfahren der GIS-Modellierung von Erreichbarkeiten für Schlaganfallversorgungszentren. Raumforsch Raumordn. 2016;74(5):437–50.CrossRef Rauch S, Rauh J. Verfahren der GIS-Modellierung von Erreichbarkeiten für Schlaganfallversorgungszentren. Raumforsch Raumordn. 2016;74(5):437–50.CrossRef
36.
go back to reference Heuschmann PU, Biegler MK, Busse O, Elsner S, Grau AJ, Hasenbein U, Hermanek P, Janzen RWC, Kolominsky-Rabas PL, Kraywinkel K, et al. Development and implementation of evidence-based indicators for measuring quality of acute stroke care: the quality Indicator Board of the German Stroke Registers Study Group (ADSR). Stroke. 2006;37(10):2573–51.CrossRef Heuschmann PU, Biegler MK, Busse O, Elsner S, Grau AJ, Hasenbein U, Hermanek P, Janzen RWC, Kolominsky-Rabas PL, Kraywinkel K, et al. Development and implementation of evidence-based indicators for measuring quality of acute stroke care: the quality Indicator Board of the German Stroke Registers Study Group (ADSR). Stroke. 2006;37(10):2573–51.CrossRef
37.
go back to reference Audebert HJ, Wimmer MLJ, Hahn R, Schenkel J, Bogdahn U, Horn M, Haberl RL, on behalf of the TEMPiS group. Can telemedicine contribute to fulfill WHO Helsingborg declaration of specialized stroke care? Cerebrovasc Dis. 2005;20(5):362–9.CrossRef Audebert HJ, Wimmer MLJ, Hahn R, Schenkel J, Bogdahn U, Horn M, Haberl RL, on behalf of the TEMPiS group. Can telemedicine contribute to fulfill WHO Helsingborg declaration of specialized stroke care? Cerebrovasc Dis. 2005;20(5):362–9.CrossRef
38.
go back to reference Correia M, Silva MR, Matos I, Magalhaes R, Lopes JC, Ferro JM, Silva MC. Prospective community-based study of stroke in northern Portugal: incidence and case fatality in rural and urban populations. Stroke. 2004;35(9):2048–53.CrossRef Correia M, Silva MR, Matos I, Magalhaes R, Lopes JC, Ferro JM, Silva MC. Prospective community-based study of stroke in northern Portugal: incidence and case fatality in rural and urban populations. Stroke. 2004;35(9):2048–53.CrossRef
39.
go back to reference Phipps MS, Jia H, Chumbler NR, Li X, Castro JG, Myers J, Williams LS, Bravata DM. Rural-urban differences in inpatient quality of care in US veterans with ischemic stroke. J Rural Health. 2014;30(1):1–6.CrossRef Phipps MS, Jia H, Chumbler NR, Li X, Castro JG, Myers J, Williams LS, Bravata DM. Rural-urban differences in inpatient quality of care in US veterans with ischemic stroke. J Rural Health. 2014;30(1):1–6.CrossRef
40.
go back to reference Rodriguez D, Cox M, Zimmer LO, Olson DM, Goldstein LB, Drew L, Peterson ED, Bushnell CD. Similar secondary stroke prevention and medication persistence rates among rural and urban patients. J Rural Health. 2011;27(4):401–8.CrossRef Rodriguez D, Cox M, Zimmer LO, Olson DM, Goldstein LB, Drew L, Peterson ED, Bushnell CD. Similar secondary stroke prevention and medication persistence rates among rural and urban patients. J Rural Health. 2011;27(4):401–8.CrossRef
41.
go back to reference Hess DC, Wang S, Hamilton W, Lee S, Pardue C, Waller JL, Gross H, Nichols FT, Hall C, Adams RJ. REACH: clinical feasibility of a rural telestroke network. Stroke. 2005;36(9):2018–20.CrossRef Hess DC, Wang S, Hamilton W, Lee S, Pardue C, Waller JL, Gross H, Nichols FT, Hall C, Adams RJ. REACH: clinical feasibility of a rural telestroke network. Stroke. 2005;36(9):2018–20.CrossRef
42.
go back to reference Wiborg A, Widder B, for the TESS study group. Teleneurology to improve stroke Care in Rural Areas: the telemedicine in stroke in Swabia (TESS) project. Stroke. 2003;34(12):2951–6.CrossRef Wiborg A, Widder B, for the TESS study group. Teleneurology to improve stroke Care in Rural Areas: the telemedicine in stroke in Swabia (TESS) project. Stroke. 2003;34(12):2951–6.CrossRef
43.
go back to reference Gonzales S, Mullen MT, Skolarus L, Thibault DP, Udoeyo U, Willis AW. Progressive rural–urban disparity in acute stroke care. Neurology. 2017;88(5):441–8.CrossRef Gonzales S, Mullen MT, Skolarus L, Thibault DP, Udoeyo U, Willis AW. Progressive rural–urban disparity in acute stroke care. Neurology. 2017;88(5):441–8.CrossRef
Metadata
Title
Two years’ experience of implementing a comprehensive telemedical stroke network comprising in mainly rural region: the Transregional Network for Stroke Intervention with Telemedicine (TRANSIT-Stroke)
Authors
Katharina M. A. Gabriel
Steffi Jírů-Hillmann
Peter Kraft
Udo Selig
Viktoria Rücker
Johannes Mühler
Klaus Dötter
Matthias Keidel
Hassan Soda
Alexandra Rascher
Rolf Schneider
Mathias Pfau
Roy Hoffmann
Joachim Stenzel
Mohamed Benghebrid
Tobias Goebel
Sebastian Doerck
Daniela Kramer
Karl Georg Haeusler
Jens Volkmann
Peter U. Heuschmann
Felix Fluri
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2020
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-020-01676-6

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