Open Access 01-12-2018 | Case report
Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
Published in: BMC Neurology | Issue 1/2018
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Background
Adenomyosis is a benign disease with elevated CA125 level.
Case presentation
We report 3 cases with adenomyosis who developed ischemic stroke during menstruation. The levels of CA125, CA19–9, and D-dimer were elevated, which dropped markedly after the menstrual phase. The development of nonbacterial thrombotic endocarditis (NBTE) and stenosis of the cerebral arteries associated with hypercoagulable state and the hyperviscosity nature of the mucinous protein may be the underlying mechanisms.
Conclusion
Our report suggests that adenomyosis might be a risk factor for ischemic stroke in middle-aged patients.