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Open Access 01-12-2018 | Case report

Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review

Authors: Keita Miyake, Takashi Hara, Etsuko Oshima, Kiyohiro Kawada, Hideki Ishizu, Yuko Yamauchi, Katsuya Satoh, Tetsuyuki Kitamoto, Shintaro Takenoshita, Seishi Terada, Norihito Yamada

Published in: BMC Neurology | Issue 1/2018

Abstract

Background

Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding.

Case presentation

We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology.

Coclusions

This is the first reported CJD case presenting with status epilepticus in the course of AD dementia.

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Title: Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
Authors: Keita Miyake
Takashi Hara
Etsuko Oshima
Kiyohiro Kawada
Hideki Ishizu
Yuko Yamauchi
Katsuya Satoh
Tetsuyuki Kitamoto
Shintaro Takenoshita
Seishi Terada
Norihito Yamada
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Neurology / Issue 1/2018
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-018-1055-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review

Abstract

Background

Case presentation

Coclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Coclusions

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