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Published in: BMC Neurology 1/2016

Open Access 01-12-2016 | Erratum

Erratum to: Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment

Authors: Elizabeth Dao, Ging-Yuek Robin Hsiung, Vesna Sossi, Claudia Jacova, Roger Tam, Katie Dinelle, John R. Best, Teresa Liu-Ambrose

Published in: BMC Neurology | Issue 1/2016

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Excerpt

After publication of the original article [1], it came to the authors’ attention that there were data entry errors in the following variables: age, sex, education, MOCA, WML volume, and ADAS-Cog. Changes have been made to Tables 1, 2, 3 and 4, to reflect the updated results, which are published in their correct version here. However, the authors note that the study conclusions have not changed.
Table 1
Descriptive characteristic
Variable
Mean
SD
Age
71.73
7.91
Female Sex, No. (%)
7
32
Education, No. (%)
 High school education
6
27
 Trade or professional certificate or diploma
2
9
 University education
14
64
MMSE (max. score 30)
27.50
1.95
MOCA (max. score 30)
23.32
2.08
WHR
0.91
0.08
BMI
26.95
4.78
PIB-positive, No. (%)
6
27.27
Global PIB BPND
0.07
0.23
WML volume (mm3), n = 16
2004.40
2761.15
Cognitive Assessments
 ADAS-Cog (max. score 70)
9.63
3.88
 Exit-25 (max. score 50)
10.59
4.38
 Stroop CW-C, sec.
61.44
26.01
 Trails B-A, sec.
50.51
24.84
 Digits F-B, sec.
3.23
2.79
SD Standard Deviation, MMSE Mini-Mental State Examination, MOCA Montreal Cognitive Assessment; WHR Waist-to-Hip Ratio, BMI Body Mass Index, ADAS-Cog Alzheimer’s Disease Assessment Scale – Cognitive subscale, Exit-25 Executive Interview Test, Stroop CW-W Stroop Color Words minus Stroop colored x’s, Trails B-A Trails B (numbers and letters) minus Trails A (numbers), Digits F-B Digits Forwards minus Digits Backwards
Table 2
Correlation matrix
 
PIB BPND
Age
Education
APOE ε4
ADAS-Cog
MOCA
EXIT 25
Digits
Stroop
Trails
PIB BPND
                   
Age
-0.00
                 
Education
-0.23
-0.39
               
APOE ε4
0.36
0.09
-0.20
             
ADAS-Cog
0.53*
0.16
-0.11
0.53*
           
MOCA
-0.54*
-0.20
0.06
-0.11
-0.45*
         
EXIT-25
0.13
0.20
-0.20
0.25
0.49*
-0.52*
       
Digits
0.02
0.17
-0.35
-0.45*
-0.30
0.13
-0.04
     
Stroop
0.17
-0.06
0.02
-0.11
0.27
-0.29
0.34
0.04
   
Trails
0.19
-0.08
-0.25
0.48*
0.15
-0.18
0.29
0.01
0.13
 
*significant at p ≤ 0.05
Table 3
Multiple linear regression models assessing the contribution of PIB retention on ADAS-Cog
Independent variables
R2
Adjusted R2
R2 Change
Unstandardized B (Standard Error)
Standardized β
P- Value
Model 1
PIB BPND
0.28
0.24
-
9.09 (3.29)
0.53
0.01
Model 2
Step 1
0.30
0.18
0.30
     
Age
     
0.07 (0.11)
0.14
0.54
Education
     
0.41 (1.86)
0.05
0.83
APOE ε4
     
4.30 (1.64)
0.53
0.02
Step 2
0.44
0.31
0.15*
     
Age
     
0.09 (0.10)
0.18
0.37
Education
     
1.15 (1.74)
0.14
0.52
APOE ε4
     
3.20 (1.59)
0.39
0.06
PIB BPND
     
7.23 (3.42)
0.42
0.05
*significant at p ≤ 0.05
Table 4
Multiple linear regression models assessing the contribution of PIB retention on MOCA
Independent variables
R2
Adjusted R2
R2 Change
Unstandardized B (Standard Error)
Standardized β
P- Value
Model 1
PIB BPND
0.29
0.26
-
-5.00 (1.74)
-0.54
0.01
Model 2
Step 1
0.05
-0.11
0.05
     
Age
     
-0.06 (0.07)
-0.21
0.41
Education
     
-0.22 (1.16)
-0.05
0.85
APOE ε4
     
-0.43 (1.02)
-0.10
0.68
Step 2
0.37
0.22
0.32*
     
Age
     
-0.07 (0.06)
-0.28
0.20
Education
     
-0.80 (0.99)
-0.18
0.43
APOE ε4
     
0.44 (0.91)
0.10
0.63
PIB BPND
     
-5.71 (1.95)
-0.62
0.01
*significant at p ≤ 0.05
Metadata
Title
Erratum to: Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment
Authors
Elizabeth Dao
Ging-Yuek Robin Hsiung
Vesna Sossi
Claudia Jacova
Roger Tam
Katie Dinelle
John R. Best
Teresa Liu-Ambrose
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2016
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-016-0673-5

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