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BMC Neurology

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Open Access 01-12-2016 | Research article

Antioxidant activity of linalool in patients with carpal tunnel syndrome

Authors: Geun-Hye Seol, Purum Kang, Hui Su Lee, Geun Hee Seol

Published in: BMC Neurology | Issue 1/2016

Abstract

Background

Carpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation on oxidative stress in patients with CTS.

Methods

This double-blind, placebo-controlled study assessed the effects of linalool inhalation on oxidative stress in patients with CTS. Thirty-seven subjects, with and without CTS, were randomized to inhalation of 1 % linalool or carrier oil. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, systolic blood pressure (sBP), diastolic blood pressure (dBP) and pulse rate were analyzed.

Results

DPPH inhibition was significantly higher in both experimental groups than in their respective controls. Moreover inhalation of linalool reduced sBP, dBP and pulse rate in the CTS group, and pulse rate in the non-CTS group. However, there were no significant differences among the study groups in nitrite levels, sBP, dBP and pulse rate.

Conclusions

Inhalation of linalool increases antioxidative activity and reduces blood pressure and pulse rate in patients with CTS.

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Title: Antioxidant activity of linalool in patients with carpal tunnel syndrome
Authors: Geun-Hye Seol
Purum Kang
Hui Su Lee
Geun Hee Seol
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Neurology / Issue 1/2016
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-016-0541-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Antioxidant activity of linalool in patients with carpal tunnel syndrome

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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