Skip to main content
Top
Published in: BMC Medical Imaging 1/2019

Open Access 01-12-2019 | Ultrasound | Research article

Assessment of peripheral muscle thickness and architecture in healthy volunteers using hand-held ultrasound devices; a comparison study with standard ultrasound

Authors: Peter Turton, Richard Hay, Ingeborg Welters

Published in: BMC Medical Imaging | Issue 1/2019

Login to get access

Abstract

Background

Pocket-sized ultrasound devices are increasingly used in a variety of clinical situations, and perform well against standard ultrasound machines. We sought to investigate if a pocket-sized ultrasound device can assess muscle thickness and architecture in healthy volunteers.

Methods

Healthy male volunteers (n = 21) across a range of ages were recruited to the study. Laying supine, ultrasound images were taken from the right anterior and lateral thigh. Thickness of the rectus femoris (RFMT), vastus intermedius (VIMT), and the two combined (anterior thigh, AMT) were measured, along with thickness of vastus lateralis (VLMT), pennation angle (VLPA) and derived fascicle length (VLFL). These scans were performed initially using a pocket-sized ultrasound (VScan) and then using a standard device (Telemed Echoblaster 128).

Results

In all six variables, there was no significant difference between the two sets of measurements. Intra-class correlation co-efficients (ICC) for VLMT, VLPA, and AMT were all excellent (0.93, 0.89, 0.90 respectively) with the derived value of VLFL having an ICC of 0.84. All ICC values were statistically significant. Regression analysis demonstrated no evidence of proportional bias in any of the measured or derived variables.

Conclusion

A pocket-sized ultrasound device gives similar measurements of lower limb muscle thickness and architecture as a standard device in healthy volunteers.
Literature
1.
go back to reference Mjolstad OC, Dalen H, Graven T, Kleinau JO, Salvesen O, Haugen BO. Routinely adding ultrasound examinations by pocket-sized ultrasound devices improves inpatient diagnostics in a medical department. Eur J Int Medicine. 2012;23:185–91.CrossRef Mjolstad OC, Dalen H, Graven T, Kleinau JO, Salvesen O, Haugen BO. Routinely adding ultrasound examinations by pocket-sized ultrasound devices improves inpatient diagnostics in a medical department. Eur J Int Medicine. 2012;23:185–91.CrossRef
2.
go back to reference Dijos M, Pucheux Y, Lafitte M, Réant P, Prevot A, Mignot A, et al. Fast track Echo of abdominal aortic aneurysm using a real pocket-ultrasound device at bedside. Echocardiography. 2012;29:285–90.CrossRef Dijos M, Pucheux Y, Lafitte M, Réant P, Prevot A, Mignot A, et al. Fast track Echo of abdominal aortic aneurysm using a real pocket-ultrasound device at bedside. Echocardiography. 2012;29:285–90.CrossRef
3.
go back to reference Troyano Luque JM, Ferrer-Roca O, Barco-Marcellán MJ, Sabatel López R, Pérez-Medina T, Pérez-Lopez FR. Modification of the hand-held Vscan ultrasound and verification of its performance for transvaginal applications. Ultrasonics. 2013;53:17–22.CrossRef Troyano Luque JM, Ferrer-Roca O, Barco-Marcellán MJ, Sabatel López R, Pérez-Medina T, Pérez-Lopez FR. Modification of the hand-held Vscan ultrasound and verification of its performance for transvaginal applications. Ultrasonics. 2013;53:17–22.CrossRef
4.
go back to reference Schleder S, Dendl L-M, Ernstberger A, Nerlich M, Hoffstetter P, Jung E-M, et al. Diagnostic value of a hand-carried ultrasound device for free intra-abdominal fluid and organ lacerations in major trauma patients. Emerg Med J. 2013;30:e20.CrossRef Schleder S, Dendl L-M, Ernstberger A, Nerlich M, Hoffstetter P, Jung E-M, et al. Diagnostic value of a hand-carried ultrasound device for free intra-abdominal fluid and organ lacerations in major trauma patients. Emerg Med J. 2013;30:e20.CrossRef
5.
go back to reference Sayasneh A, Preisler J, Smith A, Saso S, Naji O, Abdallah Y, et al. Do pocket-sized ultrasound machines have the potential to be used as a tool to triage patients in obstetrics and gynecology? Ultrasound Obstet Gynecol. 2012;40(1):45–50. Sayasneh A, Preisler J, Smith A, Saso S, Naji O, Abdallah Y, et al. Do pocket-sized ultrasound machines have the potential to be used as a tool to triage patients in obstetrics and gynecology? Ultrasound Obstet Gynecol. 2012;40(1):45–50.
6.
go back to reference Johnson GGRJ, Zeiler FA, Unger B, Hansen G, Karakitsos D, Gillman LM. Estimating the accuracy of optic nerve sheath diameter measurement using a pocket-sized, handheld ultrasound on a simulation model. Crit Ultrasound J. 2016;8:18.CrossRef Johnson GGRJ, Zeiler FA, Unger B, Hansen G, Karakitsos D, Gillman LM. Estimating the accuracy of optic nerve sheath diameter measurement using a pocket-sized, handheld ultrasound on a simulation model. Crit Ultrasound J. 2016;8:18.CrossRef
7.
go back to reference Keil-Ríos D, Terrazas-Solís H, González-Garay A, Sánchez-Ávila JF, García-Juárez I. Pocket ultrasound device as a complement to physical examination for ascites evaluation and guided paracentesis. Intern Emerg Med. 2016;11:461–6.CrossRef Keil-Ríos D, Terrazas-Solís H, González-Garay A, Sánchez-Ávila JF, García-Juárez I. Pocket ultrasound device as a complement to physical examination for ascites evaluation and guided paracentesis. Intern Emerg Med. 2016;11:461–6.CrossRef
8.
go back to reference Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, et al. Acute skeletal muscle wasting in critical illness. JAMA. 2013;310:1591.CrossRef Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, et al. Acute skeletal muscle wasting in critical illness. JAMA. 2013;310:1591.CrossRef
9.
go back to reference Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, et al. Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax. 2009;64:418–23.CrossRef Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, et al. Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax. 2009;64:418–23.CrossRef
10.
go back to reference Silva CR de S, Costa A dos S, Rocha T, de LDAM, do NT, de MSRA. Quadriceps muscle architecture ultrasonography of individuals with type 2 diabetes: reliability and applicability. PLoS One. 2018;13:e0205724.CrossRef Silva CR de S, Costa A dos S, Rocha T, de LDAM, do NT, de MSRA. Quadriceps muscle architecture ultrasonography of individuals with type 2 diabetes: reliability and applicability. PLoS One. 2018;13:e0205724.CrossRef
11.
go back to reference Souza V, Oliveira D, Cupolilo E, Miranda C, Colugnati F, Mansur H, et al. Rectus femoris muscle mass evaluation by ultrasound: facilitating sarcopenia diagnosis in pre-dialysis chronic kidney disease stages. Clinics. 2018;73:e392.PubMedPubMedCentral Souza V, Oliveira D, Cupolilo E, Miranda C, Colugnati F, Mansur H, et al. Rectus femoris muscle mass evaluation by ultrasound: facilitating sarcopenia diagnosis in pre-dialysis chronic kidney disease stages. Clinics. 2018;73:e392.PubMedPubMedCentral
12.
go back to reference Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol. 2007;102:368–73.CrossRef Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol. 2007;102:368–73.CrossRef
13.
go back to reference Young H-J, Jenkins NT, Zhao Q, Mccully KK. Measurement of intramuscular fat by muscle echo intensity. Muscle Nerve. 2015;52:963–71.CrossRef Young H-J, Jenkins NT, Zhao Q, Mccully KK. Measurement of intramuscular fat by muscle echo intensity. Muscle Nerve. 2015;52:963–71.CrossRef
14.
go back to reference Kopinski S, Engel T, Cassel M, Fröhlich K, Mayer F, Carlsohn A. Ultrasound applied to subcutaneous fat tissue measurements in international elite canoeists. Int J Sports Med. 2015;36:1134–41.CrossRef Kopinski S, Engel T, Cassel M, Fröhlich K, Mayer F, Carlsohn A. Ultrasound applied to subcutaneous fat tissue measurements in international elite canoeists. Int J Sports Med. 2015;36:1134–41.CrossRef
15.
go back to reference Rykkje A, Carlsen JF, Nielsen MB, Rykkje A, Carlsen JF, Nielsen MB. Hand-held ultrasound devices compared with high-end ultrasound systems: A systematic review. Diagnostics. 2019;9:61.CrossRef Rykkje A, Carlsen JF, Nielsen MB, Rykkje A, Carlsen JF, Nielsen MB. Hand-held ultrasound devices compared with high-end ultrasound systems: A systematic review. Diagnostics. 2019;9:61.CrossRef
16.
go back to reference Hacker ED, Peters T, Garkova M. Ultrasound assessment of the rectus Femoris cross-sectional area. West J Nurs Res. 2016;38:1221–30.CrossRef Hacker ED, Peters T, Garkova M. Ultrasound assessment of the rectus Femoris cross-sectional area. West J Nurs Res. 2016;38:1221–30.CrossRef
17.
go back to reference Mandal S, Suh E, Thompson A, Connolly B, Ramsay M, Harding R, et al. Comparative study of linear and curvilinear ultrasound probes to assess quadriceps rectus femoris muscle mass in healthy subjects and in patients with chronic respiratory disease. BMJ Open Respir Res. 2016;3:e000103.CrossRef Mandal S, Suh E, Thompson A, Connolly B, Ramsay M, Harding R, et al. Comparative study of linear and curvilinear ultrasound probes to assess quadriceps rectus femoris muscle mass in healthy subjects and in patients with chronic respiratory disease. BMJ Open Respir Res. 2016;3:e000103.CrossRef
18.
go back to reference eLima KMM, Carneiro SP. de S. Alves D, Peixinho CC, de Oliveira LF. Assessment of muscle architecture of the biceps Femoris and vastus Lateralis by ultrasound after a chronic stretching program. Clin J Sport Med. 2015;25:55–60.CrossRef eLima KMM, Carneiro SP. de S. Alves D, Peixinho CC, de Oliveira LF. Assessment of muscle architecture of the biceps Femoris and vastus Lateralis by ultrasound after a chronic stretching program. Clin J Sport Med. 2015;25:55–60.CrossRef
19.
go back to reference Turton P, Hay R, Taylor J, Mcphee J, Welters I. Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care – an observational study using ultrasound. BMC Anesthesiol. 2016;16:119. Turton P, Hay R, Taylor J, Mcphee J, Welters I. Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care – an observational study using ultrasound. BMC Anesthesiol. 2016;16:119.
20.
go back to reference Barber L, Barrett R, Lichtwark G. Validity and reliability of a simple ultrasound approach to measure medial gastrocnemius muscle length. J Anat. 2011;218:637–42.CrossRef Barber L, Barrett R, Lichtwark G. Validity and reliability of a simple ultrasound approach to measure medial gastrocnemius muscle length. J Anat. 2011;218:637–42.CrossRef
21.
go back to reference Francis CA, Hoffer JA, Reynolds S. Ultrasonographic evaluation of diaphragm thickness during mechanical ventilation in intensive care patients. Am J Crit Care. 2016;25:e1–8.CrossRef Francis CA, Hoffer JA, Reynolds S. Ultrasonographic evaluation of diaphragm thickness during mechanical ventilation in intensive care patients. Am J Crit Care. 2016;25:e1–8.CrossRef
22.
go back to reference Garcia-Vicencio S, Coudeyre E, Kluka V, Cardenoux C, Jegu A-G, Fourot A-V, et al. The bigger, the stronger? Insights from muscle architecture and nervous characteristics in obese adolescent girls. Int J Obes. 2016;40:245–51.CrossRef Garcia-Vicencio S, Coudeyre E, Kluka V, Cardenoux C, Jegu A-G, Fourot A-V, et al. The bigger, the stronger? Insights from muscle architecture and nervous characteristics in obese adolescent girls. Int J Obes. 2016;40:245–51.CrossRef
23.
go back to reference Alfredo C, Martín G, Zepeda EM, Lescas Méndez OA. Bedside ultrasound measurement of rectus Femoris: A tutorial for the nutrition support clinician. J Nutr Metab. 2017;2017:2767232. Alfredo C, Martín G, Zepeda EM, Lescas Méndez OA. Bedside ultrasound measurement of rectus Femoris: A tutorial for the nutrition support clinician. J Nutr Metab. 2017;2017:2767232.
24.
go back to reference Wojtczak J, Bonadonna P. Pocket mobile smartphone system for the point-of-care submandibular ultrasonography. Am J Emerg Med. 2013;31:573–7.CrossRef Wojtczak J, Bonadonna P. Pocket mobile smartphone system for the point-of-care submandibular ultrasonography. Am J Emerg Med. 2013;31:573–7.CrossRef
25.
go back to reference Lau BC, Motamedi D, Luke A. Use of pocket-sized ultrasound device in the diagnosis of shoulder pathology. Clin J Sport Med. 2018 Feb 14. Lau BC, Motamedi D, Luke A. Use of pocket-sized ultrasound device in the diagnosis of shoulder pathology. Clin J Sport Med. 2018 Feb 14.
27.
go back to reference Scarlata S, Mancini D, Laudisio A, Benigni A, Antonelli Incalzi R. Reproducibility and clinical correlates of supine diaphragmatic motion measured by M-mode ultrasonography in healthy volunteers. Respiration. 2018;16:1–8. Scarlata S, Mancini D, Laudisio A, Benigni A, Antonelli Incalzi R. Reproducibility and clinical correlates of supine diaphragmatic motion measured by M-mode ultrasonography in healthy volunteers. Respiration. 2018;16:1–8.
28.
go back to reference Strasser EM, Draskovits T, Praschak M, Quittan M, Graf A. Association between ultrasound measurements of muscle thickness, pennation angle, echogenicity and skeletal muscle strength in the elderly. Age (Omaha). 2013;35:2377–88.CrossRef Strasser EM, Draskovits T, Praschak M, Quittan M, Graf A. Association between ultrasound measurements of muscle thickness, pennation angle, echogenicity and skeletal muscle strength in the elderly. Age (Omaha). 2013;35:2377–88.CrossRef
29.
go back to reference Fischer A, Spiegl M, Altmann K, Winkler A, Salamon A, Themessl-Huber M, et al. Muscle mass, strength and functional outcomes in critically ill patients after cardiothoracic surgery: does neuromuscular electrical stimulation help? The Catastim 2 randomized controlled trial. Crit Care. 2016;20:30.CrossRef Fischer A, Spiegl M, Altmann K, Winkler A, Salamon A, Themessl-Huber M, et al. Muscle mass, strength and functional outcomes in critically ill patients after cardiothoracic surgery: does neuromuscular electrical stimulation help? The Catastim 2 randomized controlled trial. Crit Care. 2016;20:30.CrossRef
30.
go back to reference Kawakami Y, Abe T, Fukunaga T. Muscle-fiber pennation angles are greater in hypertrophied than in normal muscles. J Appl Physiol. 1993;74:2740–4.CrossRef Kawakami Y, Abe T, Fukunaga T. Muscle-fiber pennation angles are greater in hypertrophied than in normal muscles. J Appl Physiol. 1993;74:2740–4.CrossRef
31.
go back to reference Bodine SC, Roy RR, Meadows DA, Zernicke RF, Sacks RD, Fournier M, et al. Architectural, histochemical, and contractile characteristics of a unique biarticular muscle: the cat semitendinosus. J Neurophysiol. 1982;48:192–201.CrossRef Bodine SC, Roy RR, Meadows DA, Zernicke RF, Sacks RD, Fournier M, et al. Architectural, histochemical, and contractile characteristics of a unique biarticular muscle: the cat semitendinosus. J Neurophysiol. 1982;48:192–201.CrossRef
32.
go back to reference Ema R, Akagi R, Wakahara T, Kawakami Y. Training-induced changes in architecture of human skeletal muscles: current evidence and unresolved issues. J Phys Fit Sport Med. 2016;5:37–46.CrossRef Ema R, Akagi R, Wakahara T, Kawakami Y. Training-induced changes in architecture of human skeletal muscles: current evidence and unresolved issues. J Phys Fit Sport Med. 2016;5:37–46.CrossRef
33.
go back to reference Kumagai K, Abe T, Brechue WF, Ryushi T, Takano S, Mizuno M. Sprint performance is related to muscle fascicle length in male 100-m sprinters. J Appl Physiol. 2000;88:811–6.CrossRef Kumagai K, Abe T, Brechue WF, Ryushi T, Takano S, Mizuno M. Sprint performance is related to muscle fascicle length in male 100-m sprinters. J Appl Physiol. 2000;88:811–6.CrossRef
34.
go back to reference Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, et al. Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. J Crit Care. 2015;30:1151.e9–1151.e14.CrossRef Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, et al. Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. J Crit Care. 2015;30:1151.e9–1151.e14.CrossRef
35.
go back to reference Nishihara K, Kawai H, Kera T, Hirano H, Watanabe Y, Fujiwara Y, et al. Correlation of physical function with the thickness of multiple muscles of the quadriceps femoris in community-dwelling elderly individuals. Clin Interv Aging. 2018;13:1945–51.CrossRef Nishihara K, Kawai H, Kera T, Hirano H, Watanabe Y, Fujiwara Y, et al. Correlation of physical function with the thickness of multiple muscles of the quadriceps femoris in community-dwelling elderly individuals. Clin Interv Aging. 2018;13:1945–51.CrossRef
36.
go back to reference Ando R, Saito A, Umemura Y, Akima H. Local architecture of the vastus intermedius is a better predictor of knee extension force than that of the other quadriceps femoris muscle heads. Clin Physiol Funct Imaging. 2015;35:376–82.CrossRef Ando R, Saito A, Umemura Y, Akima H. Local architecture of the vastus intermedius is a better predictor of knee extension force than that of the other quadriceps femoris muscle heads. Clin Physiol Funct Imaging. 2015;35:376–82.CrossRef
37.
go back to reference Puthucheary ZA, McNelly AS, Rawal J, Connolly B, Sidhu PS, Rowlerson A, et al. Rectus Femoris cross-sectional area and muscle layer thickness: comparative markers of muscle wasting and weakness. Am J Respir Crit Care Med. 2017;195:136–8.CrossRef Puthucheary ZA, McNelly AS, Rawal J, Connolly B, Sidhu PS, Rowlerson A, et al. Rectus Femoris cross-sectional area and muscle layer thickness: comparative markers of muscle wasting and weakness. Am J Respir Crit Care Med. 2017;195:136–8.CrossRef
38.
go back to reference Palakshappa JA, Reilly JP, Schweickert WD, Anderson BJ, Khoury V, Shashaty MG, et al. Quantitative peripheral muscle ultrasound in sepsis: muscle area superior to thickness. J Crit Care. 2018;47:324–30.CrossRef Palakshappa JA, Reilly JP, Schweickert WD, Anderson BJ, Khoury V, Shashaty MG, et al. Quantitative peripheral muscle ultrasound in sepsis: muscle area superior to thickness. J Crit Care. 2018;47:324–30.CrossRef
39.
go back to reference Chetioui A, Masia T, Claret P-G, Markarian T, Muller L, Lefrant JY, et al. Pocket-sized ultrasound device for internal jugular puncture: A randomized study of performance on a simulation model. J Vasc Access. 2019;20:404–8.CrossRef Chetioui A, Masia T, Claret P-G, Markarian T, Muller L, Lefrant JY, et al. Pocket-sized ultrasound device for internal jugular puncture: A randomized study of performance on a simulation model. J Vasc Access. 2019;20:404–8.CrossRef
Metadata
Title
Assessment of peripheral muscle thickness and architecture in healthy volunteers using hand-held ultrasound devices; a comparison study with standard ultrasound
Authors
Peter Turton
Richard Hay
Ingeborg Welters
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Medical Imaging / Issue 1/2019
Electronic ISSN: 1471-2342
DOI
https://doi.org/10.1186/s12880-019-0373-x

Other articles of this Issue 1/2019

BMC Medical Imaging 1/2019 Go to the issue