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Published in: BMC Primary Care 1/2021

Open Access 01-12-2021 | Anticoagulant | Research

Factors influencing primary care physicians’ prescribing behavior of anticoagulant therapy for the management of patients with non-valvular atrial fibrillation in Singapore: a qualitative research study

Authors: Shera Chaterji, Lay Geok Lian, Ting Yee Lee, Liwei Chua, Sabrina Yi-Mei Wee, Sui Ling Yap, Dhana Letchimy K, Ngiap Chuan Tan

Published in: BMC Primary Care | Issue 1/2021

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Abstract

Background

Oral anticoagulant therapy use in patients with atrial fibrillation (AF) remains suboptimal in Singapore, despite the availability of both warfarin and non-vitamin K antagonist oral anticoagulants (NOACs). Primary care physicians’ (PCP) decision-making to initiate and select appropriate anticoagulant medication is pivotal in reducing complications among patients with AF. This study explored the factors influencing PCPs’ decision-making in anticoagulant initiation and anticoagulant switch for patients with non-valvular AF.

Method

The study design is qualitative research based on the theoretical framework of the Generalist Wheel of Knowledge, Understanding and Inquiry. In-depth interviews or focus group discussions were conducted with 27 PCPs in general practice in urban Singapore. The audio-recordings were transcribed and coded to identify themes, which are framed according to the “clinician”, “patient”, “medical condition and treatment” and “healthcare system and policy” domains.

Results

Personal training and experience with anticoagulant therapy; understanding patient risk-stratification; AF detection during clinical practice; medication cost; clinical support services for anticoagulation monitoring and constraints in existing care model influenced PCPs in their anticoagulant prescription. PCPs preferred to seek guidance from cardiologists in managing patients with newly diagnosed AF and attempted to engage their patients in decision-making regarding anticoagulant therapy. Some PCPs perceived sub-specialized primary care clinics focusing on AF co-management with cardiologists as an ideal setting for initiation and maintenance of anticoagulant therapy.

Conclusions

PCPs are influenced by multiple interrelated factors while making decisions on anticoagulant initiation and anticoagulant switch for patients with AF. Their proposed care model to address the barriers awaits feasibility and acceptance assessment in future research.
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Metadata
Title
Factors influencing primary care physicians’ prescribing behavior of anticoagulant therapy for the management of patients with non-valvular atrial fibrillation in Singapore: a qualitative research study
Authors
Shera Chaterji
Lay Geok Lian
Ting Yee Lee
Liwei Chua
Sabrina Yi-Mei Wee
Sui Ling Yap
Dhana Letchimy K
Ngiap Chuan Tan
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2021
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/s12875-021-01453-5

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