Skip to main content
Top
Published in: BMC Primary Care 1/2015

Open Access 01-12-2015 | Research article

Improving treatment adherence for blood pressure lowering via mobile phone SMS-messages in South Africa: a qualitative evaluation of the SMS-text Adherence SuppoRt (StAR) trial

Authors: Natalie Leon, Rebecca Surender, Kirsty Bobrow, Jocelyn Muller, Andrew Farmer

Published in: BMC Primary Care | Issue 1/2015

Login to get access

Abstract

Background

Effective use of proven treatments for high blood pressure, a preventable health risk, is challenging for many patients. Prompts via mobile phone SMS-text messaging may improve adherence to clinic visits and treatment, though more research is needed on impact and patient perceptions of such support interventions, especially in low-resource settings.

Method

An individually-randomised controlled trial in a primary care clinic in Cape Town (2012–14), tested the effect of an adherence support intervention delivered via SMS-texts, on blood pressure control and adherence to medication, for hypertensive patients. (Trial registration: ClinicalTrials.gov NCT02019823). We report on a qualitative evaluation that explored the trial participants’ experiences and responses to the SMS-text messages, and identified barriers and facilitators to delivering adherence support via patients’ own mobile phones. Two focus groups and fifteen individual interviews were conducted. We used comparative and thematic analysis approaches to identify themes and triangulated our analysis amongst three researchers.

Results

Most participants were comfortable with the technology of using SMS-text messages. Messages were experienced as acceptable, relevant and useful to a broad range of participants. The SMS-content, the respectful tone and the delivery (timing of reminders and frequency) and the relational aspect of trial participation (feeling cared for) were all highly valued. A subgroup who benefitted the most, were those who had been struggling with adherence due to high levels of personal stress. The intervention appeared to coincide with their readiness for change, and provided practical and emotional support for improving adherence behaviour. Change may have been facilitated through increased acknowledgement of their health status and attitudinal change towards greater self-responsibility. Complex interaction of psycho-social stressors and health service problems were reported as broader challenges to adherence behaviours.

Conclusion

Adherence support for treatment of raised blood pressure, delivered via SMS-text message on the patient’s own phone, was found to be acceptable, relevant and helpful, even for those who already had their own reminder systems in place. Our findings begin to identify for whom and what core elements of the SMS-text message intervention appear to work best in a low-resource operational setting, issues that future research should explore in greater depth.
Appendix
Available only for authorised users
Literature
1.
go back to reference Lim SS, Vos T, Flaxman A, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224–60.CrossRefPubMedPubMedCentral Lim SS, Vos T, Flaxman A, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224–60.CrossRefPubMedPubMedCentral
2.
go back to reference Lawes CM, Van der Hoorn S, Rodgers A. International Society of Hypertension. Global burden of blood-pressure-related disease, 2001. Lancet. 2008;371(9623):1513–8.CrossRefPubMed Lawes CM, Van der Hoorn S, Rodgers A. International Society of Hypertension. Global burden of blood-pressure-related disease, 2001. Lancet. 2008;371(9623):1513–8.CrossRefPubMed
3.
go back to reference Schroeder K, Fahey T, Ebrahim S. How can we improve adherence to blood pressure–lowering medication in ambulatory care? Systematic review of randomized controlled trials. Arch Intern Med. 2004;164(7):722–32.CrossRefPubMed Schroeder K, Fahey T, Ebrahim S. How can we improve adherence to blood pressure–lowering medication in ambulatory care? Systematic review of randomized controlled trials. Arch Intern Med. 2004;164(7):722–32.CrossRefPubMed
4.
go back to reference Gwadry-Sridhar FH, Manias E, Lal L, Salas M, Hughes DA, Ratzki-Leewing A, et al. Impact of interventions on medication adherence and blood pressure control in patients with essential hypertension: a systematic review by the ISPOR Medication Adherence And Persistence Special Interest Group. Value Health. 2013;16(5):863–71.CrossRefPubMed Gwadry-Sridhar FH, Manias E, Lal L, Salas M, Hughes DA, Ratzki-Leewing A, et al. Impact of interventions on medication adherence and blood pressure control in patients with essential hypertension: a systematic review by the ISPOR Medication Adherence And Persistence Special Interest Group. Value Health. 2013;16(5):863–71.CrossRefPubMed
5.
go back to reference Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Atun R, Car J. Mobile phone messaging reminders for attendance at healthcare appointments. Cochrane Database Syst Rev. 2013;12:CD007458.PubMed Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Atun R, Car J. Mobile phone messaging reminders for attendance at healthcare appointments. Cochrane Database Syst Rev. 2013;12:CD007458.PubMed
6.
go back to reference Leon N, Schneider H, Daviaud E. Applying a framework for assessing the health system challenges to scaling up mHealth in South Africa. BMC Med Inform Decis Mak. 2012;12:123.CrossRefPubMedPubMedCentral Leon N, Schneider H, Daviaud E. Applying a framework for assessing the health system challenges to scaling up mHealth in South Africa. BMC Med Inform Decis Mak. 2012;12:123.CrossRefPubMedPubMedCentral
8.
go back to reference Aranda-Jan CB, Mohutsiwa-Dibe N, Loukanova S. Systematic review on what works, what does not work and why of implementation of mobile health (mHealth) projects in Africa. BMC Public Health. 2014;14(1):188.CrossRefPubMedPubMedCentral Aranda-Jan CB, Mohutsiwa-Dibe N, Loukanova S. Systematic review on what works, what does not work and why of implementation of mobile health (mHealth) projects in Africa. BMC Public Health. 2014;14(1):188.CrossRefPubMedPubMedCentral
9.
go back to reference Coovadia H, Jewkes R, Barron P, Sanders D, McIntyre D. The health and health system of South Africa: historical roots of current public health challenges. Lancet. 2009;374(9692):817–34.CrossRefPubMed Coovadia H, Jewkes R, Barron P, Sanders D, McIntyre D. The health and health system of South Africa: historical roots of current public health challenges. Lancet. 2009;374(9692):817–34.CrossRefPubMed
10.
go back to reference Strategic Development Information Department City of Cape Town. District profiles (2013) using 2011 census data supplied by statistics South Africa. Cape Town: City of Cape Town; 2013. Strategic Development Information Department City of Cape Town. District profiles (2013) using 2011 census data supplied by statistics South Africa. Cape Town: City of Cape Town; 2013.
11.
go back to reference Bobrow K, Brennan T, Springer D, Levitt NS, Rayner B, Namane M, et al. Efficacy of a text messaging (SMS) based intervention for adults with hypertension: protocol for the StAR (SMS Text-message Adherence suppoRt trial) randomised controlled trial. BMC Public Health. 2014;14(1):28.CrossRefPubMedPubMedCentral Bobrow K, Brennan T, Springer D, Levitt NS, Rayner B, Namane M, et al. Efficacy of a text messaging (SMS) based intervention for adults with hypertension: protocol for the StAR (SMS Text-message Adherence suppoRt trial) randomised controlled trial. BMC Public Health. 2014;14(1):28.CrossRefPubMedPubMedCentral
12.
go back to reference Lewin S, Glenton C, Oxman AD. Use of qualitative methods alongside randomised controlled trials of complex healthcare interventions: methodological study. BMJ. 2009;339:b3496.CrossRefPubMedPubMedCentral Lewin S, Glenton C, Oxman AD. Use of qualitative methods alongside randomised controlled trials of complex healthcare interventions: methodological study. BMJ. 2009;339:b3496.CrossRefPubMedPubMedCentral
13.
go back to reference Morgan DL. Focus Group Interviewing. In: Gubrium J, Hostein J, editors. Handbook of interview research: Context and Method. California, USA: Thousand Oaks, SAGE; 2002;p141-160. Morgan DL. Focus Group Interviewing. In: Gubrium J, Hostein J, editors. Handbook of interview research: Context and Method. California, USA: Thousand Oaks, SAGE; 2002;p141-160.
14.
go back to reference Pope C, Mays N, editors. Qualitative research in health care. Third edition. Oxford: Blackwell publishing; 2006.CrossRef Pope C, Mays N, editors. Qualitative research in health care. Third edition. Oxford: Blackwell publishing; 2006.CrossRef
15.
go back to reference Bryson JM, Patton MQ, Bowman RA. Working with evaluation stakeholders: a rationale, step-wise approach and toolkit. Eval Program Plann. 2011;34(1):1–12.CrossRefPubMed Bryson JM, Patton MQ, Bowman RA. Working with evaluation stakeholders: a rationale, step-wise approach and toolkit. Eval Program Plann. 2011;34(1):1–12.CrossRefPubMed
16.
go back to reference Reynolds J, DiLiberto D, Mangham-Jefferies L, Ansah EK, Lal S, Mbakilwa H, et al. The practice of ‘doing’ evaluation: lessons learned from nine complex intervention trials in action. Implement Sci. 2014;9:75.CrossRefPubMedPubMedCentral Reynolds J, DiLiberto D, Mangham-Jefferies L, Ansah EK, Lal S, Mbakilwa H, et al. The practice of ‘doing’ evaluation: lessons learned from nine complex intervention trials in action. Implement Sci. 2014;9:75.CrossRefPubMedPubMedCentral
17.
go back to reference van der Kop ML, Karanja S, Thabane L, Marra C, Chung MH, Gelmon L, et al. In-depth analysis of patient-clinician cell phone communication during the WelTel Kenya1 antiretroviral adherence trial. PLoS One. 2012;7(9):e46033.CrossRefPubMedPubMedCentral van der Kop ML, Karanja S, Thabane L, Marra C, Chung MH, Gelmon L, et al. In-depth analysis of patient-clinician cell phone communication during the WelTel Kenya1 antiretroviral adherence trial. PLoS One. 2012;7(9):e46033.CrossRefPubMedPubMedCentral
18.
go back to reference Kagee A. Treatment adherence in South African primary health care: original research. South Afr Fam Pract. 2004;46(10):26-30. Kagee A. Treatment adherence in South African primary health care: original research. South Afr Fam Pract. 2004;46(10):26-30.
19.
go back to reference Marshall IJ, Wolfe CD, McKevitt C. Lay perspectives on hypertension and drug adherence: systematic review of qualitative research. BMJ. 2012;345:e3953.CrossRefPubMedPubMedCentral Marshall IJ, Wolfe CD, McKevitt C. Lay perspectives on hypertension and drug adherence: systematic review of qualitative research. BMJ. 2012;345:e3953.CrossRefPubMedPubMedCentral
20.
go back to reference Jennings L, Gagliardi L. Influence of mHealth interventions on gender relations in developing countries: a systematic literature review. Int J Equity Health. 2013;12:85.CrossRefPubMedPubMedCentral Jennings L, Gagliardi L. Influence of mHealth interventions on gender relations in developing countries: a systematic literature review. Int J Equity Health. 2013;12:85.CrossRefPubMedPubMedCentral
21.
go back to reference Ajzen I. The theory of planned behaviour. Organ Behav Hum Decis Process. 1991;50:179–211.CrossRef Ajzen I. The theory of planned behaviour. Organ Behav Hum Decis Process. 1991;50:179–211.CrossRef
22.
go back to reference Easthall C, Song F, Bhattacharya D. A meta-analysis of cognitive-based behaviour change techniques as interventions to improve medication adherence. BMJ Open. 2013;3(8):e002749.CrossRefPubMedPubMedCentral Easthall C, Song F, Bhattacharya D. A meta-analysis of cognitive-based behaviour change techniques as interventions to improve medication adherence. BMJ Open. 2013;3(8):e002749.CrossRefPubMedPubMedCentral
23.
go back to reference Viswanathan M, Golin CE, Jones CD, Ashok M, Blalock SJ, Wines RCM, et al. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Ann Intern Med. 2012;157(11):785–95.CrossRefPubMed Viswanathan M, Golin CE, Jones CD, Ashok M, Blalock SJ, Wines RCM, et al. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Ann Intern Med. 2012;157(11):785–95.CrossRefPubMed
24.
go back to reference Chopra M, Lawn JE, Sanders D, Barron P, Abdool Karim SS, Bradshaw D, et al. Achieving the health millennium development goals for South Africa: challenges and priorities. Lancet. 2009;374(9694):1023–31.CrossRefPubMed Chopra M, Lawn JE, Sanders D, Barron P, Abdool Karim SS, Bradshaw D, et al. Achieving the health millennium development goals for South Africa: challenges and priorities. Lancet. 2009;374(9694):1023–31.CrossRefPubMed
25.
go back to reference Peltzer K, Phaswana-Mafuya N. Patient experiences and health system responsiveness among older adults in South Africa. Global Health Action. 2012;5:1–11. Peltzer K, Phaswana-Mafuya N. Patient experiences and health system responsiveness among older adults in South Africa. Global Health Action. 2012;5:1–11.
26.
go back to reference Riley WT, Rivera DE, Atienza AA, Nilsen W, Allison SM, Mermelstein R. Health behavior models in the age of mobile interventions: are our theories up to the task? Translat Behav Med. 2011;1(1):53–71.CrossRef Riley WT, Rivera DE, Atienza AA, Nilsen W, Allison SM, Mermelstein R. Health behavior models in the age of mobile interventions: are our theories up to the task? Translat Behav Med. 2011;1(1):53–71.CrossRef
Metadata
Title
Improving treatment adherence for blood pressure lowering via mobile phone SMS-messages in South Africa: a qualitative evaluation of the SMS-text Adherence SuppoRt (StAR) trial
Authors
Natalie Leon
Rebecca Surender
Kirsty Bobrow
Jocelyn Muller
Andrew Farmer
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2015
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/s12875-015-0289-7

Other articles of this Issue 1/2015

BMC Primary Care 1/2015 Go to the issue