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Journal of Ophthalmic Inflammation and Infection

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Open Access 01-12-2016 | Letter to the Editor

Bacterial corneal ulcer associated with common variable immune deficiency

Authors: Edmund Tsui, Jie Deng, Andrew N Siedlecki, Michael E Zegans

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 1/2016

Abstract

Common variable immune deficiency (CVID) is one of the most commonly diagnosed primary immunodeficiencies. Generally, patients have a history of recurrent sinopulmonary infections, hypogammaglobulinemia of two or more immunoglobulin isotypes, and impaired functional antibody responses. Reports of corneal involvement associated with CVID are limited. We describe a case of corneal ulceration associated with methicillin-resistant Staphylococcus aureus in a patient with CVID that developed while on monthly intravenous immunoglobulin infusions and in which there were no common risk factors for bacterial keratitis, such as prior history of ocular surface disease, trichiasis, trauma, or contact lens wear.

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Title: Bacterial corneal ulcer associated with common variable immune deficiency
Authors: Edmund Tsui
Jie Deng
Andrew N Siedlecki
Michael E Zegans
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: Journal of Ophthalmic Inflammation and Infection / Issue 1/2016
Electronic ISSN: 1869-5760
DOI: https://doi.org/10.1186/s12348-016-0098-8

At a glance: The STEP trials

Springer Medicine

Bacterial corneal ulcer associated with common variable immune deficiency

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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