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Critical Care
Published in: Critical Care 5/2008

01-10-2008 | Letter

Renal failure in the intensive care unit: acute kidney injury compared to end-stage renal failure

Authors: Marlies Ostermann, René Chang, the Riyadh ICU Program Users Group

Published in: Critical Care | Issue 5/2008

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Excerpt

Patients with advanced acute kidney injury (AKI) and end-stage dialysis dependent renal failure (ESRF) are characterized by loss of renal function as well as significant associated co-morbidities. However, prognosis appears to differ when they are admitted to the intensive care unit (ICU). Patients with advanced AKI have a reported ICU mortality between 25% and 90%, depending on the specific patient population and the definition of AKI [1, 2], whereas ICU mortality in ESRF patients has been reported to be 9% to 26% [3‐5]. In contrast, Uchino and coworkers [5] found no difference in outcome between 32 ESRF patients in an ICU and 32 diagnosis and severity score matched patients with AKI treated with renal replacement therapy (RRT). …
Appendix
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Literature
1.
Mehta RL, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler A, Paganini EP, Chertow GM, for the Program of Improve Care in Acute Renal Disease: Spectrum of acute renal failure in the intensive care unit: the PICARD experience. Kidney Int 2004, 66: 1613-1621. 10.1111/j.1523-1755.2004.00927.xCrossRefPubMed
2.
Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, for the Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 2005, 294: 813-818. 10.1001/jama.294.7.813CrossRefPubMed
3.
Hutchison CA, Crowe AV, Stevens PE, Harrison DA, Lipkin GW: Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database. Crit Care 2007, 11: R50. 10.1186/cc5785PubMedCentralCrossRefPubMed
4.
Dara SI, Afessa B, Bajwa AA, Albright RC: Outcome of patients with end-stage renal disease admitted to the intensive care unit. Mayo Clin Proc 2004, 79: 1385-1390.CrossRefPubMed
5.
Uchino S, Morimatsu H, Bellomo R, Silvester W, Cole L: End-stage renal failure patients requiring renal replacement therapy in the intensive care unit: incidence, clinical features, and outcome. Blood Purif 2003, 21: 170-175. 10.1159/000069156CrossRefPubMed
Metadata
Title
Renal failure in the intensive care unit: acute kidney injury compared to end-stage renal failure
Authors
Marlies Ostermann
René Chang
the Riyadh ICU Program Users Group
Publication date
01-10-2008
Publisher
BioMed Central
Published in
Critical Care / Issue 5/2008
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc7085

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