Skip to main content
Top
Published in: Critical Care 1/2005

01-02-2004 | Review

Clinical review: Noninvasive ventilation in the clinical setting – experience from the past 10 years

Authors: Massimo Antonelli, Mariano Alberto Pennisi, Luca Montini

Published in: Critical Care | Issue 1/2005

Login to get access

Abstract

This brief review analyses the progress of noninvasive ventilation (NIV) over the last decade. NIV has gained the dignity of first line intervention for acute exacerbation of chronic obstructive pulmonary disease, assuring reduction of the intubation rate, rate of infection and mortality. Despite positive results, NIV still remains controversial as a treatment for acute hypoxemic respiratory failure, largely due to the different pathophysiology of hypoxemia. The infection rate reduction effect achieved by NIV application is crucial for immunocompromised patients for whom the endotracheal intubation represents a high risk. Improvements in skills acquired with experience over time progressively allowed successful treatment of more severe patients.
Appendix
Available only for authorised users
Literature
1.
go back to reference Torres A, Aznar R, Gatell JM, Jimenez P, Gonzalez J, Ferrer A, Celis R, Rodriguez-Roisin R: Incidence, risk and prognosis factors of nosocomial pneumonia in mechanically ventilated patients. Am Rev Respir Dis 1990, 142: 523-528.CrossRefPubMed Torres A, Aznar R, Gatell JM, Jimenez P, Gonzalez J, Ferrer A, Celis R, Rodriguez-Roisin R: Incidence, risk and prognosis factors of nosocomial pneumonia in mechanically ventilated patients. Am Rev Respir Dis 1990, 142: 523-528.CrossRefPubMed
2.
go back to reference Burns HP, Dayal VS, Scott A, Van Nostran ANP, Bryce DP: Laryngotracheal trauma: observations on its pathogenesis and its prevention following prolonged orotracheal intubation in the adult. Laryngoscope 1979, 89: 1316-1325.PubMed Burns HP, Dayal VS, Scott A, Van Nostran ANP, Bryce DP: Laryngotracheal trauma: observations on its pathogenesis and its prevention following prolonged orotracheal intubation in the adult. Laryngoscope 1979, 89: 1316-1325.PubMed
3.
go back to reference Nourdine K, Combes P, Carton MJ, Beuret P, Cannamela A, Ducreux JC: Does NIV reduce the ICU nosocomial infection risk? A prospective clinical survey. Intensive Care Med 1999, 25: 567-573. 10.1007/s001340050904CrossRefPubMed Nourdine K, Combes P, Carton MJ, Beuret P, Cannamela A, Ducreux JC: Does NIV reduce the ICU nosocomial infection risk? A prospective clinical survey. Intensive Care Med 1999, 25: 567-573. 10.1007/s001340050904CrossRefPubMed
4.
go back to reference Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F, et al.: NIV for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995, 333: 817-822. 10.1056/NEJM199509283331301CrossRefPubMed Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F, et al.: NIV for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995, 333: 817-822. 10.1056/NEJM199509283331301CrossRefPubMed
5.
go back to reference Keenan SP, Sinuff T, Cook DJ, Hill NS: Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from non-invasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med 2003, 138: 864-870.CrossRef Keenan SP, Sinuff T, Cook DJ, Hill NS: Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from non-invasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med 2003, 138: 864-870.CrossRef
6.
go back to reference Plant PK, Owen JL, Elliott MW: Non-invasive ventilation in acute exacerbations of chronic obstructive pulmonary disease: long term survival and predictors of in-hospital outcome. Thorax 2001, 56: 708-712. 10.1136/thorax.56.9.708PubMedCentralCrossRefPubMed Plant PK, Owen JL, Elliott MW: Non-invasive ventilation in acute exacerbations of chronic obstructive pulmonary disease: long term survival and predictors of in-hospital outcome. Thorax 2001, 56: 708-712. 10.1136/thorax.56.9.708PubMedCentralCrossRefPubMed
7.
go back to reference Soo Hoo GW, Santiago S, Williams AJ: Nasal mechanical ventilation for hypercapnic respiratory failure in chronic obstructive pulmonary disease: determinants of success and failure. Crit Care Med 1994, 22: 1253-1261.CrossRefPubMed Soo Hoo GW, Santiago S, Williams AJ: Nasal mechanical ventilation for hypercapnic respiratory failure in chronic obstructive pulmonary disease: determinants of success and failure. Crit Care Med 1994, 22: 1253-1261.CrossRefPubMed
8.
go back to reference Lightowler JV, Wedzicha JA, Elliott MW, Ram FS: Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. BMJ 2003, 326: 185. 10.1136/bmj.326.7382.185PubMedCentralCrossRefPubMed Lightowler JV, Wedzicha JA, Elliott MW, Ram FS: Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. BMJ 2003, 326: 185. 10.1136/bmj.326.7382.185PubMedCentralCrossRefPubMed
9.
go back to reference Carlucci A, Delmastro M, Rubini F, Fracchia C, Nava S: Changes in the practice of noninvasive ventilation in treating COPD patients over 8 years. Intensive Care Med 2003, 29: 419-425.PubMed Carlucci A, Delmastro M, Rubini F, Fracchia C, Nava S: Changes in the practice of noninvasive ventilation in treating COPD patients over 8 years. Intensive Care Med 2003, 29: 419-425.PubMed
10.
go back to reference Plant PK, Owen JL, Elliott MW: Early use of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial. Lancet 2000, 355: 1931-1935. 10.1016/S0140-6736(00)02323-0CrossRefPubMed Plant PK, Owen JL, Elliott MW: Early use of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial. Lancet 2000, 355: 1931-1935. 10.1016/S0140-6736(00)02323-0CrossRefPubMed
11.
go back to reference British Thoracic Society Standards of Care Committee: Non-invasive ventilation in acute respiratory failure. Thorax 2002, 57: 192-211. 10.1136/thorax.57.3.192CrossRef British Thoracic Society Standards of Care Committee: Non-invasive ventilation in acute respiratory failure. Thorax 2002, 57: 192-211. 10.1136/thorax.57.3.192CrossRef
12.
go back to reference Hill NS: Noninvasive ventilation for chronic obstructive pulmonary disease. Respir Care 2004, 49: 72-89.PubMed Hill NS: Noninvasive ventilation for chronic obstructive pulmonary disease. Respir Care 2004, 49: 72-89.PubMed
13.
go back to reference Wysocki M, Tric L, Wolff MA, Millet H, Herman B: Noninvasive pressure support ventilation in patients with acute respiratory failure. A randomized comparison with conventional therapy. Chest 1995, 107: 761-768.CrossRefPubMed Wysocki M, Tric L, Wolff MA, Millet H, Herman B: Noninvasive pressure support ventilation in patients with acute respiratory failure. A randomized comparison with conventional therapy. Chest 1995, 107: 761-768.CrossRefPubMed
14.
go back to reference Antonelli M, Conti G, Rocco M, Bufi M, De Blasi RA, Vivino G, Gasparetto A, Meduri GU: A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 1998, 339: 429-435. 10.1056/NEJM199808133390703CrossRefPubMed Antonelli M, Conti G, Rocco M, Bufi M, De Blasi RA, Vivino G, Gasparetto A, Meduri GU: A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 1998, 339: 429-435. 10.1056/NEJM199808133390703CrossRefPubMed
15.
go back to reference Martin TJ, Hovis JD, Costantino JP, Bierman MI, Donahoe MP, Rogers RM, Kreit JW, Sciurba FC, Stiller RA, Sanders MH: A randomized, prospective evaluation of noninvasive ventilation for acute respiratory failure. Am J Respir Crit Care Med 2000, 161: 807-813.CrossRefPubMed Martin TJ, Hovis JD, Costantino JP, Bierman MI, Donahoe MP, Rogers RM, Kreit JW, Sciurba FC, Stiller RA, Sanders MH: A randomized, prospective evaluation of noninvasive ventilation for acute respiratory failure. Am J Respir Crit Care Med 2000, 161: 807-813.CrossRefPubMed
16.
go back to reference Ferrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A: Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med 2003, 168: 1438-1444. 10.1164/rccm.200301-072OCCrossRefPubMed Ferrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A: Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med 2003, 168: 1438-1444. 10.1164/rccm.200301-072OCCrossRefPubMed
17.
go back to reference Lin M, Yang Y, Chiany H, Chang M, Chiany BN, Chitlin MD: Reappraisal of continuous positive airway pressure therapy in acute cardiogenic pulmonary edema: short-term results and long-term follow-up. Chest 1995, 107: 1379-1386.CrossRefPubMed Lin M, Yang Y, Chiany H, Chang M, Chiany BN, Chitlin MD: Reappraisal of continuous positive airway pressure therapy in acute cardiogenic pulmonary edema: short-term results and long-term follow-up. Chest 1995, 107: 1379-1386.CrossRefPubMed
18.
go back to reference Bersten AD, Holt AW, Vedic AE, Skowronski GA, Baggoley CJ: Treatment of severe cardiogenic pulmonary edema with continuous positive airway pressure delivered by face mask. N Engl J Med 1991, 325: 1825-1830.CrossRefPubMed Bersten AD, Holt AW, Vedic AE, Skowronski GA, Baggoley CJ: Treatment of severe cardiogenic pulmonary edema with continuous positive airway pressure delivered by face mask. N Engl J Med 1991, 325: 1825-1830.CrossRefPubMed
19.
go back to reference Rasanen J, Heikkila J, Downs J, Nikki P, Vaisanen I, Viitanen A: Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. Am J Cardiol 1985, 55: 296-300. 10.1016/0002-9149(85)90364-9CrossRefPubMed Rasanen J, Heikkila J, Downs J, Nikki P, Vaisanen I, Viitanen A: Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. Am J Cardiol 1985, 55: 296-300. 10.1016/0002-9149(85)90364-9CrossRefPubMed
20.
go back to reference Mehta S, Jay GD, Woolard RH, Hipona RA, Connolly EM, Cimini DM, Drinkwine JH, Hill NS: Randomized prospective trial of bilevel versus continous positive airway pressure in acute pulmonary edema. Crit Care Med 1997, 25: 620-628. 10.1097/00003246-199704000-00011CrossRefPubMed Mehta S, Jay GD, Woolard RH, Hipona RA, Connolly EM, Cimini DM, Drinkwine JH, Hill NS: Randomized prospective trial of bilevel versus continous positive airway pressure in acute pulmonary edema. Crit Care Med 1997, 25: 620-628. 10.1097/00003246-199704000-00011CrossRefPubMed
21.
go back to reference Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Casentini R, Marengo M, Giostra F, Borasi G, Groff P: Noninvasive ventilation in cardiogenic pulmonary edema. A multicenter randomized trial. Am J Respir Crit Care Med 2003, 168: 1432-1437. 10.1164/rccm.200211-1270OCCrossRefPubMed Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Casentini R, Marengo M, Giostra F, Borasi G, Groff P: Noninvasive ventilation in cardiogenic pulmonary edema. A multicenter randomized trial. Am J Respir Crit Care Med 2003, 168: 1432-1437. 10.1164/rccm.200211-1270OCCrossRefPubMed
22.
go back to reference Auriant I, Jallot A, Herve P, Cerrina J, Le Roy Ladurie F, Fournier JL, Lescot B, Parquin F: Noninvasive ventilation reduces mortality in acute respiratory failure during lung resection. Am J Respir Crit Care Med 2001, 164: 1231-1235.CrossRefPubMed Auriant I, Jallot A, Herve P, Cerrina J, Le Roy Ladurie F, Fournier JL, Lescot B, Parquin F: Noninvasive ventilation reduces mortality in acute respiratory failure during lung resection. Am J Respir Crit Care Med 2001, 164: 1231-1235.CrossRefPubMed
23.
go back to reference Confalonieri M, Potena A, Carbone G, Di Battista N, Bellone A, Baiardi P, Casentini R, Marenco M, Giostra F, Borasi G, et al.: Noninvasive ventilation in cardiogenic pulmonary edema a multicenter randomized trial. Am J Respir Crit Care Med 1999, 160: 1585-1591.CrossRefPubMed Confalonieri M, Potena A, Carbone G, Di Battista N, Bellone A, Baiardi P, Casentini R, Marenco M, Giostra F, Borasi G, et al.: Noninvasive ventilation in cardiogenic pulmonary edema a multicenter randomized trial. Am J Respir Crit Care Med 1999, 160: 1585-1591.CrossRefPubMed
24.
go back to reference Antonelli M, Conti G, Bufi M, Costa MG, Lappa A, Rocco M, Gasparetto A, Meduri GU: Noninvasive ventilation for treatment of acute respiratory failure in patients undergoing solid organ transplantation. JAMA 2000, 283: 235-241. 10.1001/jama.283.2.235CrossRefPubMed Antonelli M, Conti G, Bufi M, Costa MG, Lappa A, Rocco M, Gasparetto A, Meduri GU: Noninvasive ventilation for treatment of acute respiratory failure in patients undergoing solid organ transplantation. JAMA 2000, 283: 235-241. 10.1001/jama.283.2.235CrossRefPubMed
25.
go back to reference Hilbert G, Gruson D, Vargas F, Valentino R: Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever and acute respiratory failure. N Engl J Med 2001, 344: 481-487. 10.1056/NEJM200102153440703CrossRefPubMed Hilbert G, Gruson D, Vargas F, Valentino R: Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever and acute respiratory failure. N Engl J Med 2001, 344: 481-487. 10.1056/NEJM200102153440703CrossRefPubMed
26.
go back to reference Domenighetti G, Gayer R, Gentilini R: Noninvasive pressure support ventilation in non COPD patients with acute cardiogenic pulmonary edema and severe community acquired penumonia: acute effect and outcome. Intensive Care Med 2002, 28: 1226-1232. 10.1007/s00134-002-1373-8CrossRefPubMed Domenighetti G, Gayer R, Gentilini R: Noninvasive pressure support ventilation in non COPD patients with acute cardiogenic pulmonary edema and severe community acquired penumonia: acute effect and outcome. Intensive Care Med 2002, 28: 1226-1232. 10.1007/s00134-002-1373-8CrossRefPubMed
27.
go back to reference Antonelli M, Conti G, Moro ML, Esquinas A, Gonzalez-Diaz G, Confalonieri M, Pelaia P, Principi T, Gregoretti C, Beltrame F, et al.: Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multi center study. Intensive Care Med 2001, 27: 1718-1728. 10.1007/s00134-001-1114-4CrossRefPubMed Antonelli M, Conti G, Moro ML, Esquinas A, Gonzalez-Diaz G, Confalonieri M, Pelaia P, Principi T, Gregoretti C, Beltrame F, et al.: Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multi center study. Intensive Care Med 2001, 27: 1718-1728. 10.1007/s00134-001-1114-4CrossRefPubMed
28.
go back to reference Girou E, Schortgen F, Delclaux C, Brun-Buisson C, Blot F, Lefort Y, Lemaire F, Brochard L: Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients. JAMA 2000, 284: 2361-2367. 10.1001/jama.284.18.2361CrossRefPubMed Girou E, Schortgen F, Delclaux C, Brun-Buisson C, Blot F, Lefort Y, Lemaire F, Brochard L: Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients. JAMA 2000, 284: 2361-2367. 10.1001/jama.284.18.2361CrossRefPubMed
29.
go back to reference Girou E, Brun-Buisson C, Taille S, Lemaire F, Brochard L: Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema. JAMA 2003, 290: 2985-2991. 10.1001/jama.290.22.2985CrossRefPubMed Girou E, Brun-Buisson C, Taille S, Lemaire F, Brochard L: Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema. JAMA 2003, 290: 2985-2991. 10.1001/jama.290.22.2985CrossRefPubMed
30.
go back to reference Navalesi P, Fanfulla F, Frigerio P, Gregoretti C, Nava S: Physiologic evaluation of noninvasive mechanical ventilation delivered with three types of masks in patients with chronic hypercapnic respiratory failure. Crit Care Med 2000, 28: 1785-1790. 10.1097/00003246-200006000-00015CrossRefPubMed Navalesi P, Fanfulla F, Frigerio P, Gregoretti C, Nava S: Physiologic evaluation of noninvasive mechanical ventilation delivered with three types of masks in patients with chronic hypercapnic respiratory failure. Crit Care Med 2000, 28: 1785-1790. 10.1097/00003246-200006000-00015CrossRefPubMed
31.
go back to reference Patroniti N, Foti G, Mangio A, Coppo A, Bellini G, Pesenti A: Head helmet versus face mask for non-invasive continuous positive airway pressure: physiological study. Intensive Care Med 2003, 29: 1680-1687. 10.1007/s00134-003-1931-8CrossRefPubMed Patroniti N, Foti G, Mangio A, Coppo A, Bellini G, Pesenti A: Head helmet versus face mask for non-invasive continuous positive airway pressure: physiological study. Intensive Care Med 2003, 29: 1680-1687. 10.1007/s00134-003-1931-8CrossRefPubMed
32.
go back to reference Antonelli M, Conti G, Pelosi P, Gregoretti C, Pennisi MA, Costa R, Severgnini P, Chiaranda M, Proietti R: New treatment of acute hypoxemic respiratory failure: Non invasive pressure support ventilation delivered by helmet: a pilot controlled trial. Crit Care Med 2002, 30: 602-608. 10.1097/00003246-200203000-00019CrossRefPubMed Antonelli M, Conti G, Pelosi P, Gregoretti C, Pennisi MA, Costa R, Severgnini P, Chiaranda M, Proietti R: New treatment of acute hypoxemic respiratory failure: Non invasive pressure support ventilation delivered by helmet: a pilot controlled trial. Crit Care Med 2002, 30: 602-608. 10.1097/00003246-200203000-00019CrossRefPubMed
33.
go back to reference Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, et al.: Noninvasive positive pressure ventilation using a Helmet in patients with acute exacerbation of COPD: a feasibility study. Anesthesiology 2004, 100: 16-24. 10.1097/00000542-200401000-00007CrossRefPubMed Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, et al.: Noninvasive positive pressure ventilation using a Helmet in patients with acute exacerbation of COPD: a feasibility study. Anesthesiology 2004, 100: 16-24. 10.1097/00000542-200401000-00007CrossRefPubMed
34.
go back to reference Girault C, Daudenthun I, Chevron V, Tamion F, Leroy , Bonmarchand G: Noninvasive ventilation as a systematic extubation and weaning technique in acute on chronic respiratory failure: a prospective randomized controlled study. Am J Respir Crit Care Med 1999, 160: 86-92.CrossRefPubMed Girault C, Daudenthun I, Chevron V, Tamion F, Leroy , Bonmarchand G: Noninvasive ventilation as a systematic extubation and weaning technique in acute on chronic respiratory failure: a prospective randomized controlled study. Am J Respir Crit Care Med 1999, 160: 86-92.CrossRefPubMed
35.
go back to reference Nava S, Ambrosino N, Clini E, Prato M, Orlando G, Vitacca M, Brigada P, Fracchia C, Rubini F: Noninvasive mechanical in the weaning of patients with respiratory failure due to COPD: a randomized controlled study. Ann Intern Med 1998, 128: 721-728.CrossRefPubMed Nava S, Ambrosino N, Clini E, Prato M, Orlando G, Vitacca M, Brigada P, Fracchia C, Rubini F: Noninvasive mechanical in the weaning of patients with respiratory failure due to COPD: a randomized controlled study. Ann Intern Med 1998, 128: 721-728.CrossRefPubMed
36.
go back to reference Ferrer M, Esquinas A, Arancibia F, Thonmas Bauer T, Gonzalez G, Carrillo A, Rodriguez-Roisin R, Torres A: Noninvasive ventilation during persistent weaning failure: a randomized controlled trial. Am J Respir Crit Care Med 2003, 168: 70-76. 10.1164/rccm.200209-1074OCCrossRefPubMed Ferrer M, Esquinas A, Arancibia F, Thonmas Bauer T, Gonzalez G, Carrillo A, Rodriguez-Roisin R, Torres A: Noninvasive ventilation during persistent weaning failure: a randomized controlled trial. Am J Respir Crit Care Med 2003, 168: 70-76. 10.1164/rccm.200209-1074OCCrossRefPubMed
37.
go back to reference International Consensus Conferences in Intensive Care Medicine: Noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 2001, 163: 283-291.CrossRef International Consensus Conferences in Intensive Care Medicine: Noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 2001, 163: 283-291.CrossRef
38.
go back to reference Keenan SP, Powers C, Mc Cormack DG, Block G: Noninvasive positive-pressure ventilation for poextubation respiratory distress: a randomized controlled trial. JAMA 2002, 287: 3238-3244. 10.1001/jama.287.24.3238CrossRefPubMed Keenan SP, Powers C, Mc Cormack DG, Block G: Noninvasive positive-pressure ventilation for poextubation respiratory distress: a randomized controlled trial. JAMA 2002, 287: 3238-3244. 10.1001/jama.287.24.3238CrossRefPubMed
39.
go back to reference Esteban A, Frutos-Vivar F, Ferguson ND, Arabi Y, Apzteguia C, Gonzalez M, Epstein SK, Hill NS, Nava S, Soares MA, et al.: Non-invasive positive pressure ventilation for respiratory failure after extubation. N Engl J Med 2004, 350: 2452-2460. 10.1056/NEJMoa032736CrossRefPubMed Esteban A, Frutos-Vivar F, Ferguson ND, Arabi Y, Apzteguia C, Gonzalez M, Epstein SK, Hill NS, Nava S, Soares MA, et al.: Non-invasive positive pressure ventilation for respiratory failure after extubation. N Engl J Med 2004, 350: 2452-2460. 10.1056/NEJMoa032736CrossRefPubMed
Metadata
Title
Clinical review: Noninvasive ventilation in the clinical setting – experience from the past 10 years
Authors
Massimo Antonelli
Mariano Alberto Pennisi
Luca Montini
Publication date
01-02-2004
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2005
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc2933

Other articles of this Issue 1/2005

Critical Care 1/2005 Go to the issue