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Critical Care

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Open Access 01-04-2004 | Research

Quality of life of survivors from severe sepsis and septic shock may be similar to that of others who survive critical illness

Authors: Cristina Granja, Cláudia Dias, Altamiro Costa-Pereira, António Sarmento

Published in: Critical Care | Issue 2/2003

Abstract

Introduction

The objective of the present study was to compare the health-related quality of life (HR-QoL) of survivors from severe sepsis and septic shock with HR-QoL in others who survived critical illness not involving sepsis.

Methods

From March 1997 to March 2001, adult patients in an eight-bed medical/surgical intensive care unit (ICU) of a tertiary care hospital admitted with severe sepsis or septic shock (sepsis group; n = 305) were enrolled and compared with patients admitted without sepsis (control group; n = 392). Patients younger than 18 years (n = 48) and those whose ICU stay was 1 day or less (n = 453) were excluded. In addition, patients exhibiting nonsevere sepsis on admission were excluded (n = 87). Finally, patients who developed nonsevere sepsis or severe sepsis/septic shock after admission were also excluded (n = 88).

Results

In-hospital mortality rates were 34% in the sepsis group and 26% in the control group. There were no differences in sex, age, main activity (work status), and previous health state between groups. Survivors in the sepsis group had a significantly higher Acute Physiology and Chronic Health Evaluation II score on admission (17 versus 12) and stayed significantly longer in the ICU. A follow-up appointment was held 6 months after ICU discharge, and an EQ-5D (EuroQol five-dimension) questionnaire was administered. A total of 104 sepsis survivors and 133 survivors in the control group answered the EQ-5D questionnaire. Sepsis survivors reported significantly fewer problems only in the anxiety/depression dimension. Although there were no significant differences in the other dimensions of the EQ-5D, there was a trend towards fewer problems being reported by sepsis survivors.

Conclusion

Evaluation using the EQ-5D at 6 months after ICU discharge indicated that survivors from severe sepsis and septic shock have a similar HR-QoL to that of survivors from critical illness admitted without sepsis.

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Title: Quality of life of survivors from severe sepsis and septic shock may be similar to that of others who survive critical illness
Authors: Cristina Granja
Cláudia Dias
Altamiro Costa-Pereira
António Sarmento
Publication date: 01-04-2004
Publisher: BioMed Central
Published in: Critical Care / Issue 2/2003
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc2818

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Quality of life of survivors from severe sepsis and septic shock may be similar to that of others who survive critical illness

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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