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Critical Care
Published in: Critical Care 3/2014

Open Access 01-06-2014 | Letter

The furosemide stress test to predict renal function after continuous renal replacement therapy

Authors: Peter HJ van der Voort, E Christiaan Boerma, Peter Pickkers

Published in: Critical Care | Issue 3/2014

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Excerpt

We read with interest the recent article by Dr Chawla and colleagues showing that a furosemide stress test was able to predict the development of renal damage stage III according to the Acute Kidney Injury Network classification in critically ill patients [1]. In this study, 25 patients that subsequently developed acute kidney injury (AKI) had lower urine output 2 hours following administration of furosemide compared with 52 patients that did not develop AKI. Apart from predicting which patients will develop AKI based on the renal response to furosemide, this concept may possibly also be used to predict successful recovery of renal function after continuous renal replacement therapy (CRRT) in critically ill patients recovering from AKI. …
Literature
1.
Chawla LS, Davison DL, Brasha-Mitchell E, Koyner JL, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Kimmel PL, Seneff MG: Development and standardization of a furosemide stress test to predict the severity of acute kidney injury. Crit Care 2013, 17: R207. 10.1186/cc13015PubMedPubMedCentralCrossRef
2.
Wu VC, Ko WJ, Chang HW, Chen YW, Lin YF, Shiao CC, Chen YM, Chen YS, Tsai PR, Hu FC, Yang JY, Lin YH, Wu KD: Risk factors of early redialysis after weaning from postoperative acute renal replacement therapy. Intensive Care Med 2008, 34: 101-108. 10.1007/s00134-007-0813-xPubMedCrossRef
3.
Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Straaten HO, Ronco C, Kellum JA: Discontinuation of continuous renal replacement therapy: a post hoc analysis of a prospective multicenter observational study. Crit Care Med 2009, 37: 2576-2582. 10.1097/CCM.0b013e3181a38241PubMedCrossRef
4.
van der Voort PH, Boerma EC, Koopmans M, Zandberg M, de Ruiter J, Gerritsen RT, Egbers PH, Kingma WP, Kuiper MA: Furosemide does not improve renal recovery after hemofiltration for acute renal failure in critically ill patients: a double blind randomized controlled trial. Crit Care Med 2009, 37: 533-538. 10.1097/CCM.0b013e318195424dPubMedCrossRef
5.
Hasannejad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khandang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H: Interactions of human organic anion transporters with diuretics. J Pharmacol Exp Therap 2004, 308: 1021-1029.CrossRef
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Bowman RH: Renal secretion of [35-S]furosemide and depression by albumin binding. Am J Physiol 1975, 229: 93-98.PubMed
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Burg M, Stoner L, Cardinal J, Green N: Furosemide effect on isolated perfused tubules. Am J Physiol 1973, 225: 119-124.PubMed
Metadata
Title
The furosemide stress test to predict renal function after continuous renal replacement therapy
Authors
Peter HJ van der Voort
E Christiaan Boerma
Peter Pickkers
Publication date
01-06-2014
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2014
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc13871

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