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Critical Care
Published in: Critical Care 3/2014

Open Access 01-06-2014 | Commentary

Using procalcitonin to guide antimicrobial duration in sepsis: asking the same questions will not bring different answers

Authors: Jorge IF Salluh, Vandack Nobre, Pedro Povoa

Published in: Critical Care | Issue 3/2014

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Abstract

Severe sepsis is a major healthcare problem and the early initiation of antimicrobials is one of the few measures associated with improved outcomes. However, antibiotic overuse is an increasing problem in critical care. Of several potential biomarkers for antibiotic stewardship, procalcitonin represents the most widely studied and validated. In this commentary we address the current literature on the use of biomarkers to guide antimicrobial therapy in the critically ill and discuss its limitations and future directions.
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Metadata
Title
Using procalcitonin to guide antimicrobial duration in sepsis: asking the same questions will not bring different answers
Authors
Jorge IF Salluh
Vandack Nobre
Pedro Povoa
Publication date
01-06-2014
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2014
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc13870

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