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Critical Care
Published in: Critical Care 5/2013

01-10-2013 | Commentary

Acute kidney injury: the dilemma of organ failures or just a circular reference?

Authors: Anne-Sophie Guilbert, Pierre Tissières

Published in: Critical Care | Issue 5/2013

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Abstract

Whether the egg or the chicken came first remains debated, although the debate is not critical for those who love eating omelets. At least, it is well accepted that one needs to break eggs to fry an omelet. In some ways, there are similarities with acute kidney injury. A lot of debate arises from whether acute kidney injury is a complication of various insults and therapies or an expected continuum of the organ failure process. Indeed, it is well accepted that acute renal failure is associated with increased mortality in severely ill children and infants.
Literature
1.
Zwiers AJ, de Wildt SN, Hop WC, Dorresteijn EM, Gischler SJ, Tibboel D, Cransberg K: Acute kidney injury is a frequent complication in critically ill neonates on extracorporeal membrane oxygenation: a 14-year cohort study. Crit Care 2013, 17: R151. 10.1186/cc12830PubMedCentralCrossRefPubMed
2.
Vincent JL, Nelson DR, Williams MD: Is worsening multiple organ failure the cause of death in patients with severe sepsis? Crit Care Med 2011, 39: 1050-1055. 10.1097/CCM.0b013e31820eda29CrossRefPubMed
3.
Leteurtre S, Duhamel A, Grandbastien B, Proulx F, Cotting J, Gottesman R, Joffe A, Wagner B, Hubert P, Martinot A, Lacroix J, Leclerc F: Daily estimation of the severity of multiple organ dysfunction syndrome in critically ill children. CMAJ 2010, 182: 1181-1187. 10.1503/cmaj.081715PubMedCentralCrossRefPubMed
4.
Bestati N, Leteurtre S, Duhamel A, Proulx F, Grandbastien B, Lacroix J, Leclerc F: Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study. Crit Care 2010, 14: R202. 10.1186/cc9323PubMedCentralCrossRefPubMed
5.
Takasu O, Gaut JP, Watanabe E, To K, Fagley RE, Sato B, Jarman S, Efimov IR, Janks DL, Srivastava A, Bhayani SB, Drewry A, Swanson PE, Hotchkiss RS: Mechanisms of cardiac and renal dysfunction in patients dying of sepsis. Am J Respir Crit Care Med 2013, 187: 509-517. 10.1164/rccm.201211-1983OCPubMedCentralCrossRefPubMed
Metadata
Title
Acute kidney injury: the dilemma of organ failures or just a circular reference?
Authors
Anne-Sophie Guilbert
Pierre Tissières
Publication date
01-10-2013
Publisher
BioMed Central
Published in
Critical Care / Issue 5/2013
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc12873

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