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01-12-2012 | Commentary

The role of natural killer cells in the pathogenesis of sepsis: the ongoing enigma

Authors: Julia Bohannon, Yin Guo, Edward R Sherwood

Published in: Critical Care | Issue 6/2012

Abstract

The study by Souza-Fonseca-Guimaraes and colleagues in the previous issue of Critical Care shows several alterations in blood natural killer (NK) characteristics during human sepsis and systemic inflammatory response syndrome, including changes in NK cell numbers, Toll-like receptor (TLR) expression, and responsiveness to TLR agonists. This paper advances our knowledge of NK cell biology during sepsis and provides the background for future investigations.

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Herzig DS, Driver BR, Fang G, Toliver-Kinsky TE, Shute EN, Sherwood ER: Regulation of lymphocyte trafficking by CXC chemokine receptor 3 during septic shock. Am J Respir Crit Care Med 2012, 185: 291-300. 10.1164/rccm.201108-1560OCPubMedCentralCrossRefPubMed

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Title: The role of natural killer cells in the pathogenesis of sepsis: the ongoing enigma
Authors: Julia Bohannon
Yin Guo
Edward R Sherwood
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Critical Care / Issue 6/2012
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc11881

At a glance: The STEP trials

Springer Medicine

The role of natural killer cells in the pathogenesis of sepsis: the ongoing enigma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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