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Critical Care
Published in: Critical Care 5/2012

01-10-2012 | Commentary

Measuring glomerular filtration rate in acute kidney injury: Yes, but not yet

Author: Bruce A Molitoris

Published in: Critical Care | Issue 5/2012

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Abstract

Acute kidney injury has become a major focus for nephrologists and critical care physicians. The development of structural biomarkers is proceeding, but the results to date have been disappointing. The use of a shortened creatinine clearance as a functional acute kidney injury biomarker is not new but has not been compared with that of other diagnostic approaches. A rapid, repeatable, and accurate measured glomerular filtration rate would be the gold standard for a functional biomarker and is not far off.
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Wang E, Meier DJ, Sandoval RM, Von Hendy-Willson VE, Pressler BM, Bunch RM, Alloosh M, Sturek MS, Schwartz GJ, Molitoris BA: A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals. Kidney Int. 2012, 81: 112-117. 10.1038/ki.2011.294.CrossRefPubMed
Metadata
Title
Measuring glomerular filtration rate in acute kidney injury: Yes, but not yet
Author
Bruce A Molitoris
Publication date
01-10-2012
Publisher
BioMed Central
Published in
Critical Care / Issue 5/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11482

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