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Critical Care
Published in: Critical Care 3/2012

01-06-2012 | Commentary

Crystalloids versus colloids during acute normovolemic anemia: the quest continues...

Authors: Karl Schebesta, Oliver Kimberger

Published in: Critical Care | Issue 3/2012

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Abstract

The optimal kind of fluid for fluid resuscitation during acute, severe hemorrhage is still discussed controversially. Of particular interest in this context is the choice of colloids versus crystalloids and their effect on the critical hemoglobin level. In a previous issue of Critical Care, Pape and colleagues describe the effect of four different volume replacement options on the critical hemoglobin concentration, and show marked differences for the different treatments. Even though some important pathophysiological issues remain unsolved, the current manuscript adds interesting evidence to an ongoing quest.
Literature
1.
Pape A, Kutschker S, Kertscho H, Stein P, Horn O, Lossen M, Zwissler B, Habler O: The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs. Crit Care 2012, 16: R69. 10.1186/cc11324PubMedCentralCrossRefPubMed
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Meier J, Kemming GI, Kisch-Wedel H, Wolkhammer S, Habler OP: Hyperoxic ventilation reduces 6-hour mortality at the critical hemoglobin concentration. Anesthesiology 2004, 100: 70-76. 10.1097/00000542-200401000-00014CrossRefPubMed
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Pestel GJ, Fukui K, Kimberger O, Hager H, Kurz A, Hiltebrand LB: Hemodynamic parameters change earlier than tissue oxygen tension in hemorrhage. J Surg Res 2010, 160: 288-293. 10.1016/j.jss.2008.11.002CrossRefPubMed
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Spahn DR, Leone BJ, Reves JG, Pasch T: Cardiovascular and coronary physiology of acute isovolemic hemodilution: a review of nonoxygen-carrying and oxygen-carrying solutions. Anesth Analg 1994, 78: 1000-1021.CrossRefPubMed
Metadata
Title
Crystalloids versus colloids during acute normovolemic anemia: the quest continues...
Authors
Karl Schebesta
Oliver Kimberger
Publication date
01-06-2012
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11364

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