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Breast Cancer Research
Published in: Breast Cancer Research 5/2013

01-10-2013 | Viewpoint

Pregnancy offers new insights into mechanisms of breast cancer risk and resistance

Authors: D Joseph Jerry, Grace Makari-Judson, Giovanna M Crisi, Karen A Dunphy

Published in: Breast Cancer Research | Issue 5/2013

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Abstract

Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets. The results suggest new biomarkers that may improve risk prediction and provide endpoints for assessment of clinical responses to prophylactic therapies.
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Metadata
Title
Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
Authors
D Joseph Jerry
Grace Makari-Judson
Giovanna M Crisi
Karen A Dunphy
Publication date
01-10-2013
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 5/2013
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr3482

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