Published in:
01-02-2012 | Editorial
Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed
Authors:
Laura Stanbery, Elizabeth M Petty
Published in:
Breast Cancer Research
|
Issue 1/2013
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Abstract
Septins comprise a conserved family of GTPase proteins. Of these, human SEPT9 has been widely implicated in cancers of epithelial origin, including breast cancer, as well as leukemia. In a previous issue of Breast Cancer Research, Connolly and colleagues present compelling data further supporting a role for SEPT9 isoforms in early breast cancer development as well as evidence suggesting that cellular localization patterns of SEPT9 isoforms may contribute to oncogenesis.