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01-06-2009 | Editorial

The transition from ductal carcinoma in situto invasive breast cancer: the other side of the coin

Author: Stuart J Schnitt

Published in: Breast Cancer Research | Issue 1/2009

Abstract

The factors associated with the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer are poorly understood. Many studies of this subject focus on the role of molecular and genetic alterations in the neoplastic epithelial cells. However, emerging evidence suggests that transition from DCIS to invasive cancer is strongly dependent upon alterations in the microenvironment. The potential roles of myoepithelial cells and of stromal-epithelial interaction are of particular interest in this regard.

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Title: The transition from ductal carcinoma in situto invasive breast cancer: the other side of the coin
Author: Stuart J Schnitt
Publication date: 01-06-2009
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue 1/2009
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr2228

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