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Breast Cancer Research
Published in: Breast Cancer Research 1/2008

01-02-2008 | Review

Mechanisms of metastasis

Authors: Kent W Hunter, Nigel PS Crawford, Jude Alsarraj

Published in: Breast Cancer Research | Special Issue 1/2008

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Abstract

Metastasis is an enormously complex process that remains to be a major problem in the management of cancer. The fact that cancer patients might develop metastasis after years or even decades from diagnosis of the primary tumor makes the metastatic process even more complex. Over the years many hypotheses were developed to try to explain the inefficiency of the metastatic process, but none of these theories completely explains the current biological and clinical observations. In this review we summarize some of the proposed models that were developed in attempt to understand the mechanisms of tumor dissemination and colonization as well as metastatic progression.
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Metadata
Title
Mechanisms of metastasis
Authors
Kent W Hunter
Nigel PS Crawford
Jude Alsarraj
Publication date
01-02-2008
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2008
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1988

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