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Breast Cancer Research
Published in: Breast Cancer Research 2/2008

01-05-2008 | Poster presentation

Assessment of angiogenesis in the hyperplasia preinvasive, invasive breast carcinoma sequence

Authors: JE Bluff, SS Cross, NJ Brown, MW Reed, CA Staton

Published in: Breast Cancer Research | Special Issue 2/2008

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Excerpt

Tissue factor (TF), the primary initiator of coagulation, has been shown to stimulate angiogenesis, which is crucial for the development and metastasis of solid tumours, in part by upregulating vascular endothelial growth factor A (VEGF). Angiogenesis in invasive breast cancer is well documented, but little is known about the role of angiogenesis in premalignant breast disease, or when the angiogenic switch occurs during the development of breast malignancy. This study therefore quantifies angiogenesis, VEGF and TF in the hyperplasia, preinvasive, invasive breast carcinoma sequence. …
Metadata
Title
Assessment of angiogenesis in the hyperplasia preinvasive, invasive breast carcinoma sequence
Authors
JE Bluff
SS Cross
NJ Brown
MW Reed
CA Staton
Publication date
01-05-2008
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 2/2008
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1930

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