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Published in: Breast Cancer Research 1/2000

01-03-2000 | Meeting abstract

Screening for BRCA1 gene mutations by capillary electrophoretic REF-SSCP

Authors: P Kringen, HG Eiken, JC Pedersen, S Egedal, K Berg, KM Tveit, TI Andersen

Published in: Breast Cancer Research | Special Issue 1/2000

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Excerpt

The identification of novel mutations in large genes requires efficient mutation-scanning techniques. Except for DNA-sequencing and PTT (protein truncation test), SSCP (single strand conformation polymorphism) is the technique that has been the most extensively applied to scan for mutations in the BRCA1-gene. In the present study a capillary electrophoretic (CE) restriction endonuclease fingerprinting (REF) modification of the SSCP technique was established for BRCA1 exon 11. …
Metadata
Title
Screening for BRCA1 gene mutations by capillary electrophoretic REF-SSCP
Authors
P Kringen
HG Eiken
JC Pedersen
S Egedal
K Berg
KM Tveit
TI Andersen
Publication date
01-03-2000
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2000
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr176

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