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Breast Cancer Research
Published in: Breast Cancer Research 3/2007

01-06-2007 | Review

Tumour dormancy in breast cancer: an update

Authors: Muriel Brackstone, Jason L Townson, Ann F Chambers

Published in: Breast Cancer Research | Issue 3/2007

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Abstract

Delayed recurrences, common in breast cancer, are well explained by the concept of tumour dormancy. Numerous publications describe clinical times to disease recurrence or death, using mathematical approaches to infer mechanisms responsible for delayed recurrences. However, most of the clinical literature discussing tumour dormancy uses data from over a half century ago and much has since changed. This review explores how current breast cancer treatment could change our understanding of the biology of breast cancer tumour dormancy, and summarizes relevant experimental models to date. Current knowledge gaps are highlighted and potential areas of future research are identified.
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Metadata
Title
Tumour dormancy in breast cancer: an update
Authors
Muriel Brackstone
Jason L Townson
Ann F Chambers
Publication date
01-06-2007
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 3/2007
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1677

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